2025-26 NBA Playoff Odds: Spreads, Lines for Second-Round Series

Now the NBA playoffs are in the swing of things.

Let’s check out the odds for the second round of the playoffs, at DraftKings Sportsbook as of May 11.

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EAST SECOND ROUND

No. 7 PHILADELPHIA vs. No. 3 NEW YORK
NYK wins 4-0

No. 4 CLEVELAND (+200) vs. No. 1 DETROIT (-250) 
DET leads 2-1

GAME 4 — DET @ CLE (May 11)

Spread: Cavs -3.5
Moneyline: Pistons +140, Cavs -166
O/U: 213.5

What to know: This has been a weird series. Each team has yet to lose on its home court, and the games haven’t seen much domination on either side. Take Game 3 for example: Cleveland held Detroit to 18 points in the second quarter and took a 16-point lead into halftime. Then, in the third quarter, the Pistons held the Cavs to 19 points, cutting that deficit to two heading into the fourth. But Cleveland put together its highest-scoring quarter of the game in the final frame to emerge with a seven-point win.

WEST SECOND ROUND

No. 4 LOS ANGELES (+7000) vs. No. 1 OKLAHOMA CITY (-20000)
OKC leads 3-0

GAME 4 — OKC @ LAL (May 11)

Spread: Thunder -11.5
Moneyline: Thunder -520, Lakers +390
O/U: 214.5

What to know: It appears the Lakers just don’t have the firepower to compete with the Thunder. OKC has won the first three games of the series by a combined 59 points (19.7 points per game), including a 23-point win in Game 3 in Los Angeles. And consider this: SGA is averaging just 21 points per game on 46% shooting. The Thunder are stacked, and sit at 7-0 in the postseason so far. 

No. 6 MINNESOTA (+320) vs. No. 3 SAN ANTONIO (-390) 
Tied 2-2

GAME 5 — MIN @ SAS (May 12)

Spread: Spurs -10.5
Moneyline: Spurs -410, Wolves +320
O/U: 218.5

What to know: We’ve got a series on our hands. Now tied at 2-2, both of these teams have won once at home and once on the other team’s home floor, with the Wolves winning a crucial Game 4 in Minnesota. But that wasn’t the story of the night. Victor Wembanyama was assessed a Flagrant 2 in the first half of Game 4, and was ejected from the game, after hitting Naz Reid with a vicious elbow to the head. He will play Game 5, but how chippy might things be after that?