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Tennessee Titans at Detroit Lions: Predictions, picks and odds for NFL Week 8 game

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On paper, the Detroit Lions (5-1) vs. the Tennessee Titans (1-5) is a lopsided matchup, but it’s the NFL and anything can happen.

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Tennessee surprised most of the league when it jumped out to a 10-0 lead against the Buffalo Bills with Mason Rudolph at quarterback. Then Buffalo woke up and scored 34 straight points for a blowout win. Things aren’t looking good in Tennessee, but an upset victory in Detroit could be a huge momentum boost.

There’s a new leader in the powerful NFC North after Detroit handed the Minnesota Vikings their first loss of the season. On a four-game win streak, the offense continues to find the endzone and is proving to be a legit Super Bowl contender.

PROP TALK: These are the best prop bets for NFL games this week 

Lions vs. Titans odds, moneyline, over/under

The Lions are favorites to defeat the Titans, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2024 including the ESPN BET app and Fanatics Sportsbook promo code.

  • Spread: Lions (-11)
  • Moneyline: Lions (-600); Titans (+425)
  • Over/under: 45.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Thursday Night Football odds and Monday Night Football odds.

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NFL Week 8 odds, predictions and picks

Rams vs. Vikings | Browns vs. Ravens | Lions vs. Titans | Texans vs. Colts | Jaguars vs. Packers | Dolphins vs. Cardinals | Patriots vs. Jets | Buccaneers vs. Falcons | Bengals vs. Eagles | Chargers vs. Saints | Seahawks vs. Bills | Commanders vs. Bears | Broncos vs. Panthers | Raiders vs. Chiefs | 49ers vs. Cowboys | Steelers vs. Giants 

Lorenzo Reyes: Lions 41, Titans 14

In another situation this week when a one-win team is facing a legitimate Super Bowl contender, the Titans may once again start Mason Rudolph, depending on the health of Will Levis. Still, offensive coordinator Ben Johnson has built a system that allows Jared Goff to flourish. I think Detroit rolls here with ease.

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Tyler Dragon: Lions 30, Titans 17

Detroit’s won four straight games. Jared Goff is playing like an MVP candidate. The Lions have the NFL’s third-ranked scoring offense. The Titans won’t be able to score enough points to keep up with Detroit. This one might get out of hand early.

Richard Morin: Lions 35, Titans 12

This one has blowout written all over it.

Jordan Mendoza: Lions 34, Titans 13

It should be a win if Tennessee doesn’t lose by more than 10 points. Fun fact: Detroit is looking for their first win over Tennessee this century. The last time it beat the team was in 1995 when it was the Houston Oilers.

MOST VALUABLE BET: Who is the favorite to win NFL MVP in 2024? 



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