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‘Yo-yo’ weight loss occurs because of this surprising reason

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‘Yo-yo’ weight loss occurs because of this surprising reason

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About 40% of American adults live with obesity — and for many, it can feel a bit like a roller-coaster ride as their weight fluctuates up and down.

The cycle of losing and regaining weight, commonly known as the yo-yo effect, could be due to a type of “metabolic memory,” in which the body remembers and strives to return to its former state of obesity, according to a new study.

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“Obesity is a chronic condition with significant metabolic consequences, strongly linked to various metabolic and cardiovascular diseases,” study author Dr. Ferdinand von Meyenn, assistant professor for nutrition and metabolic epigenetics at ETH Zurich in Switzerland, told Fox News Digital.

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“A well-documented observation is that the body tends to defend increased body weight, making weight loss and maintenance notoriously challenging.”

Obesity is a common chronic disease in the U.S., with one in five children and two out of five adults meeting the criteria, according to the Centers for Disease Control and Prevention (CDC).

The cycle of losing and regaining weight on repeat, commonly known as the yo-yo effect, could be due to a type of “metabolic memory,” a new study found. (iStock)

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The new research, published in November in the journal Nature, points to epigenetics (genetic activity) that may play a role in regaining weight after weight loss. 

What is epigenetics?

“Epigenetics, which involves chemical markers that influence gene activity without altering the DNA sequence, is crucial in how cells function and respond to environmental factors,” Dr. Fatima Cody Stanford, obesity medicine physician at Massachusetts General Hospital and Harvard Medical School, told Fox News Digital.

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“These markers can be altered by lifestyle factors, such as diet, and can remain stable for years, effectively creating a cellular ‘memory’ of past states, such as obesity,” added Stanford, who was not part of the study.

It is well-known that cells keep their genetic identity as they divide. The researchers were curious about what happens to fat cells — which live on average for 10 years before the body replaces them, von Meyenn said.

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The researchers investigated what happens to fat cells, which live on average for 10 years before the body replaces them. (iStock)

This differs from other cells in tissues, which divide much faster – intestinal cells, for example, generally divide every other week, he added. 

Fat cells still must adapt to external stimuli and undergo epigenetic adaptations, von Meyenn noted.

The researchers set out to determine whether these changes could be reversed.

Fighting ‘memory’ in fat cells 

In mouse studies, the researchers found that even after significant weight loss, their cells have a “memory” of obesity encoded in the epigenome, which controls the activity of genes, said von Meyenn.

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“Our study indicates that one reason maintaining body weight after initial weight loss is difficult is that the fat cells remember their prior obese state and likely aim to return to this state,” he told Fox News Digital.

“The body tends to defend increased body weight, making weight loss and maintenance notoriously challenging.” 

“This means one would have to ‘fight’ this obesogenic memory to maintain body weight.”

Based on this research, a failure to maintain weight loss after dieting is not necessarily due to lack of effort or willpower, but could also be driven by an underlying biological phenomenon, von Meyenn added.

Potential limitations 

The research looked only at fatty tissue, and the genetic mechanisms were studied only in mice. Even so, the researchers said they believe that similar mechanisms also apply to humans. 

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Other experts cautioned, however, that the study shows only association and does not prove that epigenetic changes cause the yo-yo effect.

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“The authors pointed out that they cannot say for certain that the epigenetic modifications directly cause people to regain their lost weight, nor pinpoint which specific epigenetic markers may be driving this effect,” Petronella Ravenshear, board-certified nutritionist and author of “The Human Being Diet,” told Fox News Digital.

Florida-based Ravenshear, who was not part of the study, noted that the results should not lead people to claim, “It’s not my fault, it’s my genes!”

Plans for future research

“We will need to now expand, see how the memory can be erased and whether other cells or tissues are also affected, [such as] the brain or the liver,” von Meyenn said.

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It’s possible that if people maintain a healthy weight for a year or longer after dieting, that may be enough time to erase the memory in fat cells, according to Ravenshear.

The term “diet,” in its original connotation, means “way of living” — but it is now synonymous with short-term dietary changes that are unsustainable, one expert said. (iStock)

“This discovery underscores the importance of preventing obesity, particularly in children and adolescents, to avoid establishing this epigenetic memory that complicates long-term weight management,” Stanford noted.

“Understanding these mechanisms further could lead to more effective treatments and prevention strategies, emphasizing the need for a proactive approach to weight management from an early age,” she added. 

‘Way of living’

The term “diet,” in its original connotation, means “way of living” — but it is now synonymous with short-term dietary changes that are unsustainable, Ravenshear noted.

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People often regain the weight they lose when they return to the eating habits that led to weight gain in the first place, many experts agree.

Ravenshear cited Professor David Benton at Swansea University in the U.K., author of “Tackling the Obesity Crisis,” who recently shared in a Guardian interview, “The mantra is that diets fail.”

One expert recommends focusing on breaking addictions to sugar and refined carbohydrates and embracing a new way of eating. (iStock)

“They fail because to avoid regaining lost weight, you need to permanently change your diet.”

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After finishing a diet, many people return to the previous lifestyle that caused the problem in the first place, he noted.

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“Frequently snacking, and eating calorie-dense, nutrient-poor foods, disrupts our blood sugar, raises insulin levels and adds to inflammation – and the inflammation itself makes it harder to lose weight,” Ravenshear told Fox News Digital.

“Eating calorie-dense, nutrient-poor foods disrupts our blood sugar, raises insulin levels and adds to inflammation – and the inflammation itself makes it harder to lose weight,” one expert cautioned. (iStock)

She recommends focusing on breaking addictions to sugar and refined carbohydrates and embracing a new way of eating.

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The expert suggests choosing nutrient-dense whole foods, eating three meals a day, and fasting with nothing but water for five hours between meals.

 

The weight loss occurs as a side effect of rebalanced hormones and lowered inflammation, she noted.

Ravenshear added, “When we are getting the calories, but not the nutrients that our body and brain need, we’re always hungry because our brain drives us to keep searching for food.”

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Aging in Place: How Technology Might Help You Grow Old at Home

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Aging in Place: How Technology Might Help You Grow Old at Home

Dr. Megan Jack, a neurosurgeon in Cleveland, often works 60 or 70 hours a week. And she’s completely unavailable when she’s in the operating room. That makes it tough to be a caregiver for her 76-year-old mother, who lives in a separate unit on Dr. Jack’s property, 30 minutes away from the hospital.

To help care for her mother, who has Alzheimer’s disease, Dr. Jack uses an array of high-tech tools, some of which didn’t exist just a few years ago. She manages her mother’s medications with a smart pill box. She changes her television channels with an app, sends appointment reminders through a digital message board — and, with her mother’s blessing, uses cameras for communication and monitoring.

“It’s been invaluable that I can both make sure she’s safe and make sure everything is going well,” Dr. Jack said, “but also give her the independence and the freedom that she still deserves.”

America is aging rapidly. Roughly 11,000 people are turning 65 each day in the United States. And many of them — 75 percent of people over 50, according to AARP’s most recent survey, from 2024 — hope to spend their remaining years in the comfort of their homes, rather than in assisted-living or other care facilities.

One thing that could help fulfill those wishes is the budding field of “age tech,” which encompasses tools that support older adults. Industry experts say that age tech is making homes safer for older adults and is easing the minds of their caregivers, especially those who live far away or work outside the home.

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Dr. Jack said that age tech had “really allowed me to integrate caregiving into my life, as opposed to caregiving taking over my life.”

If older adults don’t have loved ones who are both close by and able to help, they might believe they don’t have a ton of options. They can live independently, or, if they can afford it and qualify medically, they can move to an assisted-living facility or a nursing home, without a lot of choices in between. In-home help can be expensive without Medicaid and can also be difficult to find, given the serious shortage of home care workers.

Age tech can help bridge some important gaps, said Emily Nabors, the associate director of innovation at the National Council on Aging, a nonprofit advocacy group. Already, AARP reports that 25 percent of caregivers are remotely monitoring their loved ones with apps, videos or wearables, nearly double the percentage from five years ago.

“We used to say homes are the health care settings of the future, but they really are health care settings now,” Ms. Nabors said. “Aging in place is very realistic.”

More than 700 companies are in AARP’s AgeTech Collaborative, a group that connects businesses, nonprofits and funders to help get new technologies off the ground. Altogether, the collaborative’s start-ups have raised nearly $1 billion in the past four years.

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The products include smart walkers, glasses with lenses that provide real-time captions of conversations for those with hearing issues, and a concierge service that connects older people to drivers and deliveries, even if they don’t have a smartphone.

Ms. Nabors does foresee some affordability and access barriers to age tech, including the lack of high-speed internet in rural areas, but she said one vital resource would be local aging agencies, which can offer advice and, sometimes, free support.

Janet Marasa leaned on the agency near her home in Rockland County, N.Y., to get a free robotic pet for her mother, Carol DeMaio, 80, who has dementia. The pets, manufactured by a company called Joy for All, aim to offer emotional support without the upkeep.

Ms. DeMaio named the robotic dog Sabrina, after a golden retriever who died. The new Sabrina stays at the foot of her bed at night. As soon as Ms. DeMaio stirs awake, the dog reacts. “She said it gives her a reason to get up in the morning,” Ms. Marasa said.

The dog has been a boon to her, too. “It provides comfort and interaction that I can’t provide every second,” said Ms. Marasa, who lives with her mother but works full time for the county government. “It gives her something that she can feel like is totally her own.”

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In Broward County, Fla., where the population of residents over 85 is expected to nearly triple over the next few decades, the local agency on aging has used state and federal money and private grants to provide technologies to nearly 4,000 of the county’s seniors at no cost.

Its offerings include a company that uses radar to sense falls and a program that allows seniors to make video calls through their televisions.

“The possibilities are endless,” Charlotte Mather-Taylor, the agency’s chief executive, said. “It’s pretty great to see all the new technology coming out so quickly, and I think that can only benefit our older population and also our caregivers.”

Even technologies not specifically marketed as age tech can help older adults maintain their independence, said Laurie Orlov, founder of the blog Aging and Health Technology Watch. She pointed to video-calling and telehealth platforms; remotely controlled thermostats and lights; and smart speakers, doorbells and watches.

“All technology can be customized to help older adults stay longer in their homes and help their family members feel good about it, or at least tolerate it,” Ms. Orlov said.

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That will only become more true with the continued proliferation of artificial intelligence, Ms. Orlov added. Some older adults are already using conversational A.I. to get answers about things like the weather or their medications. (Relying too heavily on A.I. can, however, have negative consequences because chatbots often give flawed medical advice and can lead patients astray.) A.I. can also assist in pattern detection: alerting caregivers to signals that might indicate declines in someone’s cognition or mental health, such as changing their speech pattern or leaving the house less frequently.

One A.I.-powered age tech tool is ElliQ, a tabletop companion robot that looks like a sleek silver desk lamp with a screen. About a year and a half ago, Camille Wolsonovich got one for free, thanks to a local nonprofit, for her 90-year-old father, Bill Castellano. He lives alone in a senior community.

Ms. Wolsonovich, who runs a consulting business, relies on ElliQ to lead her father in exercises and remind him to take his pills and drink water. The robot also asks her father about his sleep and mood via automated check-ins.

“Everything’s just another layer that gives us more confidence, from a caregiving standpoint, that he’s good,” Ms. Wolsonovich said. “I don’t have to necessarily track everything all the time and be overbearing.”

As for Mr. Castellano? He plays trivia digitally and converses daily with ElliQ. The robot, which has a friendly female voice, asks questions, cracks jokes and remembers his likes, dislikes and friends. “She’s great company,” he said. “Everybody around me wants one.”

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Clara Berridge studies the ethics of age tech at the University of Washington.

She has many privacy concerns, namely that most direct-to-consumer products aren’t subject to medical privacy laws, despite being privy to sensitive health information. Though she hopes the federal government will eventually step in to regulate these products, as it has in other countries, the onus remains on the consumer for now.

And even if an age tech product isn’t selling mom’s personal data to the lowest bidder, Dr. Berridge said there’s still the question of whether certain tools are ethical.

“It’s really important for caregivers to recognize that using these new technologies that give them more information about someone can represent greater intrusion into someone’s life,” she said.

What may be well-intentioned monitoring could reveal information that an older adult would rather keep private, such as issues with incontinence, or the comings and goings of a romantic partner.

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“It can lead to somebody feeling infantilized,” Dr. Berridge said. “Like there’s not a place to hide within your own home.”

Her research shows that adult children often underestimate how much their parents can understand about technology and how much they want to be involved in tech-related decisions.

She encouraged caregivers to have transparent conversations about privacy implications and to avoid ultimatums or the idea that any decision must be permanent. She said caregivers should put themselves in their parents’ shoes: Is this something they’d want their own children monitoring?

Dr. Berridge is working on an advanced directive for technology, which outlines older people’s wishes for how technology is used in their care. Ultimately, she hopes that questions about age tech will become a standard part of planning for the future.

“If you’re at the start of what, for many people, ends up being a long road of supporting someone potentially through the end of their life,” she said, “seeking to understand each other’s concerns and priorities better is time very well spent.”

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Grieving mom hospitalized with rare ‘broken heart syndrome’ after veteran son’s suicide

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Grieving mom hospitalized with rare ‘broken heart syndrome’ after veteran son’s suicide

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A distraught mother who thought she was having a heart attack was instead hospitalized with broken heart syndrome — otherwise known as takotsubo syndrome (TTS) — less than a year after her veteran son tragically took his own life.

Dawn Turner, 57, of the U.K., lost her son in August of last year. 

Just last month, the mom of three awoke with “unbearable” chest pains, she said — and called an ambulance, worried she was going into cardiac arrest. But when she arrived at the hospital, doctors told her she was suffering from the effects of grief caused by a broken heart, as news agency SWNS reported. 

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TTS is a temporary, reversible heart condition often triggered by extreme emotional or physical stress, such as grief, fear or severe illness, according to experts.

Symptoms usually mimic a heart attack, with sudden and severe chest pain and shortness of breath the most common — and it primarily affects women over the age of 50.

A mom whose soldier son took his own life feared she was suffering cardiac arrest — only to be told by hospital doctors that she was feeling the effects of grief caused by a broken heart. Dawn Turner, mother of deceased soldier Rob Homans, is pictured above, April 2026. (SWNS)

Turner, of Eckington in Worcester, said, “I was [sitting] downstairs earlier that night and thought I had a bit of indigestion. I went to bed and just couldn’t get comfortable — I was breaking out in a sweat and had heart palpitations.

“Then, around midnight, I had pain down my arm and in my jaw. I was still putting it down to indigestion… My partner Paul asked me if I was all right, and I said, ‘I think I’m having a heart attack.’”

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She said she couldn’t catch her breath — “and my heart felt as though it was missing a beat and then [started] thudding again. For those moments, I truly believed I was having a heart attack.”

“Your heart is all over the place — there’s an extra beat,” Turner was told. 

She said her partner called emergency services, and an ambulance arrived within five minutes.

“They came in and linked me up to an ECG. They said, ‘Your heart is all over the place — there’s an extra beat, and it’s all over the place,’” she said, as SWNS reported. 

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Turner was rushed to the hospital by ambulance.

Turner is shown with her son in full dress uniform. He worked as an artilleryman and spent 10 years in the U.K.’s Royal Horse Artillery after joining in 2006. He was battling mental health challenges after his military service, and ultimately took his own life. (SWNS)

In emergency care, Turner was also given blood tests.

She added, “They came back and said I didn’t have the enzymes produced from a heart attack in my blood. But they said there [was] something going on.”

After undergoing more tests and seeing a cardiologist, Turner was told she had takotsubo syndrome.

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“I told [the doctor] that my heart feels broken. I told her about [my son] Rob, and she said it’s exactly that. She said it’s a real thing, and that I’d been under so much stress. The body can only take so much, and the grief and the stress can be quite physical.”

Turner’s son committed suicide in August 2025 after struggling to get help with his mental health.

He spent 10 years in the Royal Horse Artillery after joining in 2006, when he worked as an artilleryman.

Turner’s son did two tours of duty in Afghanistan, she said. After he returned to civilian life, he began suffering from a number of health conditions. She’s shown above with a flower-draped memorial to her son. (SWNS)

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He did two tours of duty in Afghanistan, she said, and returned to civilian life in 2016 before suffering several worsening health conditions.

Turner, who is also the CEO of a veterans charity called Stepway, “When he left the army, he got married, and they settled down in London. He walked straight into a job as a delivery driver. But then his health took a downward spiral, and he started having digestive troubles.”

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He was eventually told he had PTSD — but those symptoms may be similar to those of mild traumatic brain injury, Turner said.

“He was deaf in one ear from using the guns,” she said. “He realized he was putting so much pressure on his marriage, so he moved back up with me. He started to build himself up — then COVID hit.”

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Turner said there were unfortunate delays as her son tried to get access to various services and facilities.

“When people lose loved ones, you’re obviously distraught, but you eventually find closure,” she said, per SWNS. “I found peace when I lost my sister in 2015. But with Rob, I can’t find closure because there’s no justice there.”

“I had never really understood that a person could become so overwhelmed by stress and grief that it physically affects the heart,” said the grieving mom. “Broken heart syndrome can look and feel like a heart attack.” (iStock)

Turner is now on the mend and hopes to be fully recovered in a couple of weeks, SWNS reported. 

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“Until that moment, I had never really understood that a person could become so overwhelmed by stress and grief that it physically affects the heart,” she shared. “Broken heart syndrome can look and feel like a heart attack. It was a warning sign for me, and for anyone. It can change the shape of one of your heart chambers … it can cause some serious damage.”

She added, “The cardiologist told me that thankfully, my heart itself is healthy and there was no damage, but that it will take around two weeks to a month for my heart to reboot itself.”

“Maybe the extra [heart]beat is for Rob. You are carrying on living for him,” her partner told her. 

Turner was told she needed to rest, seek counseling and make lifestyle changes to reduce stress.

“Things have settled down, and I’m taking things easy — I’m pacing myself now, and I feel a lot better. Paul said, ‘Maybe the extra beat is for Rob. You are carrying on living for him.’”

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Turner said, “That broke me and healed me a little bit all at once.”

Fox News Digital previously reported that broken heart syndrome, which causes the heart to temporarily weaken, has been linked to the brain’s reaction to stress, as studies have found. 

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In an article published in the European Heart Journal in March 2019, Swiss researchers said they found that the syndrome is linked to the way the brain communicates with the heart.

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Broken heart syndrome, which causes the heart to temporarily weaken, has been linked to the brain’s reaction to stress, studies have found. (iStock)

Caused by intense emotional events, TTS is a rare, temporary condition that weakens the left ventricle and disrupts its normal pumping function.

The syndrome causes the heart’s main pumping chamber to change shape and get larger. The heart muscle becomes weaker, and its pumping action loses strength. 

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Symptoms include sudden, intense chest pain, pressure or heaviness in the chest, along with shortness of breath. 

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It is treated with beta blockers and blood-thinning medicine to reduce risks of clots and other flareups.

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GLP-1s Don’t Work for Everyone: What To Know if You’re Not Seeing Results

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GLP-1s Don’t Work for Everyone: What To Know if You’re Not Seeing Results


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GLP-1 Not Working? Here’s Why and Alternatives That Can Help




















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