Connect with us

Health

Multiple myeloma, rare blood cancer: Bruce Springsteen's wife's diagnosis spotlights the illness

Published

on

Multiple myeloma, rare blood cancer: Bruce Springsteen's wife's diagnosis spotlights the illness

Join Fox News for access to this content

Plus special access to select articles and other premium content with your account – free of charge.

By entering your email and pushing continue, you are agreeing to Fox News’ Terms of Use and Privacy Policy, which includes our Notice of Financial Incentive.

Please enter a valid email address.

Having trouble? Click here.

Patti Scialfa, Bruce Springsteen’s wife and a member of the E Street Band, recently shared that she was diagnosed in 2018 with a type of blood cancer called multiple myeloma.

She revealed her illness in the documentary “Road Diary: Bruce Springsteen and the E Street Band,” which premiered at the Toronto Film Festival on Sept. 8. 

Advertisement

The production gives a behind-the-scenes look at the famed musician and the long-standing band during their latest tour.

BRUCE SPRINGSTEEN’S WIFE ANNOUNCES BLOOD CANCER DIAGNOSIS

“This affects my immune system, so I have to be careful what I choose to do and where I choose to go,” Scialfa, 71, said in the film when discussing her illness.

Patti Scialfa, Bruce Springsteen’s wife and a member of the E Street Band, recently shared that she was diagnosed in 2018 with a type of blood cancer called multiple myeloma. (Getty Images)

“Every once in a while, I come to a show or two and I can sing a few songs on stage, and that’s been a treat,” she continued. 

Advertisement

Scialfa joined the E Street Band right before the 1984 “Born in the U.S.A.” tour. She later married Springsteen in 1991 and was inducted into the Rock and Roll Hall of Fame in 2014.

Fox News Digital reached out to Scialfa for comment.

What is multiple myeloma?

Multiple myeloma, a cancer of the cells in the bone marrow, is diagnosed in more than 35,000 people in the U.S. each year, according to the American Cancer Society.

Plasma cells grow in the bone marrow, which has been described as a “factory” of blood. 

NEW PROSTATE CANCER MEDICATION ‘SHOWS PROMISE’ IN TREATING AGGRESSIVE DISEASE, STUDY FINDS

Advertisement

In a healthy person, the cells produce proteins called antibodies that are directed against germs to fight infection, according to Dr. Cristina Gasparetto, a hematologic oncologist and professor of medicine at Duke University School of Medicine.

Multiple myeloma occurs when plasma cells grow “out of control,” the ACS states.

Multiple myeloma occurs when plasma cells grow “out of control,” per the American Cancer Society. (iStock)

That causes abnormal antibodies to be secreted in the blood, which can damage the bones and other organs.

“[The disease] is called ‘multiple’ because there are frequently multiple patches or areas in the bone where it grows,” Dr. Joseph Mikhael, chief medical officer of the International Myeloma Foundation in California, told Fox News Digital.

Advertisement

Symptoms of the disease

“Most of the signs and symptoms of myeloma are rather general, with the top three being excessive fatigue, bone pain and anemia,” Mikhael said.

Some patients, however, may not have any symptoms when they are diagnosed.

The most common symptoms can be summed up in the acronym “CRAB,” which stands for high calcium levels in the blood, renal (or kidney) insufficiency, anemia and bone destruction, experts say.

The top three symptoms of the disease are excessive fatigue, bone pain and anemia, experts say.

Bone pain is the hallmark of the disease, as the myeloma cells grow within the bone, which may lead to elevated levels of calcium in the blood, Gasparetto told Fox News Digital.

Advertisement

“Symptoms of having high calcium include increased thirst, dehydration, fatigue, muscle pain and sometimes confusion,” she added.

Multiple myeloma is diagnosed in more than 35,000 people in the U.S. each year, according to the American Cancer Society. (iStock)

The antibodies produced by the myeloma cells are eliminated through the kidneys, which can cause obstruction and/or direct damage to the organs.

“The patient will notice some foamy urine, due to the presence of an abundant amount of an [abnormal] protein called Bence-Jones proteinuria,” Gasparetto said.

Methods of diagnosis

The first step is typically to administer specific blood and urine tests, which reveal abnormally high protein levels excreted by the tumor cells – often referred to as an “M spike,” experts told Fox News Digital.

Advertisement

“We measure this protein at the time of diagnosis, during therapy to assess response, and thereafter to monitor progression or relapse,” Gasparetto said.

BREAST CANCER DRUG COULD HELP PROLONG SURVIVAL FOR CHILDREN WITH BRAIN TUMORS, STUDY FINDS

Bone pain may also prompt imaging, which would reveal any skeletal abnormalities.

The initial results are then confirmed with a bone aspiration and biopsy.

“With the bone marrow aspiration, we remove a small amount of fluid from the bone marrow, and with the bone marrow biopsy, we remove a small piece of bone,” Gasparetto said.

Advertisement

Myeloma does not typically run in families, but there is a slightly increased incidence when a family member has the disease, experts say. (iStock)

A pathologist then analyzes the sample to determine the severity of the disease.

The final diagnosis is based on a combination of all these tests — blood work, bone marrow aspiration and biopsy, imaging studies and urinalysis, experts told Fox News Digital.

Risk factors for the disease

Myeloma does not typically run in families, but there is a slightly increased incidence when a family member has the disease, Mikhael told Fox News Digital.

“For the vast majority of cases, we do not know the cause of myeloma.”

Advertisement

Many cases may be due to random genetic changes that occur later in life, experts say.

“For the vast majority of cases, we do not know the cause of myeloma,” Mikhael said. “It is more common as we age, with the average age of diagnosis approximately 69.”

      

African-American and Latino American patients are diagnosed at a younger age, on average at around 64 or 65.

Individuals of African descent are twice as likely to have myeloma, statistics show.

Advertisement

Multiple myeloma is more common as people age, doctors say, with the average age of diagnosis approximately 69. (iStock)

Firefighters who have been exposed to fires are more at risk, and other types of chemical exposures are also connected to myeloma, including Agent Orange and excessive radiation, Mikhael noted.

There may also be a greater risk for people who have a higher increased body mass index, as well as in people who have certain blood conditions, such as monoclonal gammopathy of undetermined significance (MGUS), which involves an abnormal protein in the blood without the organ damage caused by multiple myeloma.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

In most cases, multiple myeloma cannot be prevented, according to Dr. Mikkael Sekeres, chief of the division of hematology of Sylvester Cancer Center at the University of Miami.

Advertisement

Treatment options

The American Cancer Society recommends that myeloma patients see an oncologist for a personalized treatment plan based on their age, overall health and severity of the disease.

Some therapies may include monoclonal antibodies and drugs called immune modulating agents, which boost the immune system to help the body fight cancer.

“Multiple myeloma can [also] be treated with chemotherapy — up to three or four drug regimens for a few months, followed by maintenance therapy,” a doctor said. (iStock)

“Multiple myeloma can [also] be treated with chemotherapy — up to three or four drug regimens for a few months, followed by maintenance therapy,” Sekeres told Fox News Digital.

Eligible patients may pursue a bone marrow (stem cell) transplant, which can lead to prolonged remissions, the doctor added.

Advertisement

For more Health articles, visit www.foxnews.com/health

The cancer is not cured with conventional therapy, but most patients respond well to treatment, according to Mikhael.

“The average survival rate was one or two years just 20 years ago, but it is now over 10 years,” he noted.

Health

How Well Will You Age? Take Our Quiz to Find Out.

Published

on

How Well Will You Age? Take Our Quiz to Find Out.

Every day we’re faced with a zillion small choices: Go to sleep early, or watch one more episode of that Netflix drama. Call an old friend to catch up, or cruise social media. Of course, no single action will guarantee a long, healthy life or doom you to an early grave. But those little daily decisions do add up, and over the long term they can make a difference when it comes to both your longevity and your health span, the amount of life spent in relatively good health.

Scroll through this theoretical “day in the life” and select the option that best fits your typical day. Not every situation will apply perfectly, but think about which choice you’d be most likely to make. This isn’t a formal scientific assessment. The goal here isn’t to assign you a “good” or “bad” score, but to help you understand the central factors that shape the way we age and how long we live.

Continue Reading

Health

Red hair may be increasing as study points to surprising evolution trend

Published

on

Red hair may be increasing as study points to surprising evolution trend

NEWYou can now listen to Fox News articles!

A study from Harvard Medical School indicates natural selection has favored the red hair gene, resulting in a potential increase in the number of redheaded people as humanity continues to evolve.

By analyzing nearly 16,000 ancient genomes spanning 10,000 years, researchers identified a list of traits that nature is actively pushing forward. Among the most prominent were the genetic variants for red hair.

“Perhaps having red hair was beneficial 4,000 years ago, or perhaps it came along for the ride with a more important trait,” the authors noted.

22 HEALTH CARE PREDICTIONS FOR 2025 FROM MEDICAL RESEARCHERS

Advertisement

The study, published in the journal Nature, relied on a large database of ancient DNA from West Eurasia. Using new computing methods, the team was able to filter out random fluctuations in DNA to identify what it called “directional selection.”

Directional selection happens when a particular version of a gene gives an organism a strong survival or reproductive advantage, causing it to become more common in a population faster than it would by chance, according to experts.

Directional selection is when a specific gene provides such significant benefits that it rises in frequency across a population much faster than random chance. (iStock)

Prior to this study, scientists only knew of about 21 such instances in human history, one of which was lactose tolerance. This new research uncovered hundreds more.

“With these new techniques and a large amount of ancient genomic data, we can now watch how selection shaped biology in real time,” Ali Akbari, first author of the study and senior staff scientist in the lab of Harvard geneticist David Reich, said in a press release.

Advertisement

COMMON EATING HABIT MAY TRIGGER PREMATURE IMMUNE SYSTEM AGING, STUDY FINDS

The data showed that genetic markers for red hair are among 479 gene variants that have been strongly favored over the past 10,000 years. One likely explanation, the researchers said, is a major shift in human history: the transition to farming.

Scientists have long pointed to vitamin D synthesis as a likely driver for the rise of traits like fair skin and light hair. (iStock)

As humans moved away from hunting and gathering and settled into agricultural societies, their environment and behavior changed radically, triggering an evolutionary “acceleration.”

CLICK HERE FOR MORE HEALTH STORIES

Advertisement

While the Harvard study provides the first definitive statistical proof that red hair was actively selected during the rise of farming, the researchers noted that the exact prehistoric benefit still requires more study.

However, scientists have long pointed to vitamin D synthesis as a likely driver for the rise of these light-pigmented traits in northern climates.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER

While redheads remain a minority of the global population today, the Harvard study’s analysis suggests that they may not be an evolutionary accident.

While redheads remain a minority of the global population today, the Harvard study’s analysis suggests they may not be an evolutionary accident. (iStock)

Advertisement

Instead, the red hair trait was “boosted” by natural selection as humans adapted to the challenges of a modern world, according to the researchers.

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ

The researchers urged caution in how these findings are interpreted.

CLICK HERE TO DOWNLOAD THE FOX NEWS APP

“What a variant is associated with now is not necessarily why an allele propagated,” the authors noted.

Advertisement

Continue Reading

Health

Aging in Place: How Technology Might Help You Grow Old at Home

Published

on

Aging in Place: How Technology Might Help You Grow Old at Home

Dr. Megan Jack, a neurosurgeon in Cleveland, often works 60 or 70 hours a week. And she’s completely unavailable when she’s in the operating room. That makes it tough to be a caregiver for her 76-year-old mother, who lives in a separate unit on Dr. Jack’s property, 30 minutes away from the hospital.

To help care for her mother, who has Alzheimer’s disease, Dr. Jack uses an array of high-tech tools, some of which didn’t exist just a few years ago. She manages her mother’s medications with a smart pill box. She changes her television channels with an app, sends appointment reminders through a digital message board — and, with her mother’s blessing, uses cameras for communication and monitoring.

“It’s been invaluable that I can both make sure she’s safe and make sure everything is going well,” Dr. Jack said, “but also give her the independence and the freedom that she still deserves.”

America is aging rapidly. Roughly 11,000 people are turning 65 each day in the United States. And many of them — 75 percent of people over 50, according to AARP’s most recent survey, from 2024 — hope to spend their remaining years in the comfort of their homes, rather than in assisted-living or other care facilities.

One thing that could help fulfill those wishes is the budding field of “age tech,” which encompasses tools that support older adults. Industry experts say that age tech is making homes safer for older adults and is easing the minds of their caregivers, especially those who live far away or work outside the home.

Advertisement

Dr. Jack said that age tech had “really allowed me to integrate caregiving into my life, as opposed to caregiving taking over my life.”

If older adults don’t have loved ones who are both close by and able to help, they might believe they don’t have a ton of options. They can live independently, or, if they can afford it and qualify medically, they can move to an assisted-living facility or a nursing home, without a lot of choices in between. In-home help can be expensive without Medicaid and can also be difficult to find, given the serious shortage of home care workers.

Age tech can help bridge some important gaps, said Emily Nabors, the associate director of innovation at the National Council on Aging, a nonprofit advocacy group. Already, AARP reports that 25 percent of caregivers are remotely monitoring their loved ones with apps, videos or wearables, nearly double the percentage from five years ago.

“We used to say homes are the health care settings of the future, but they really are health care settings now,” Ms. Nabors said. “Aging in place is very realistic.”

More than 700 companies are in AARP’s AgeTech Collaborative, a group that connects businesses, nonprofits and funders to help get new technologies off the ground. Altogether, the collaborative’s start-ups have raised nearly $1 billion in the past four years.

Advertisement

The products include smart walkers, glasses with lenses that provide real-time captions of conversations for those with hearing issues, and a concierge service that connects older people to drivers and deliveries, even if they don’t have a smartphone.

Ms. Nabors does foresee some affordability and access barriers to age tech, including the lack of high-speed internet in rural areas, but she said one vital resource would be local aging agencies, which can offer advice and, sometimes, free support.

Janet Marasa leaned on the agency near her home in Rockland County, N.Y., to get a free robotic pet for her mother, Carol DeMaio, 80, who has dementia. The pets, manufactured by a company called Joy for All, aim to offer emotional support without the upkeep.

Ms. DeMaio named the robotic dog Sabrina, after a golden retriever who died. The new Sabrina stays at the foot of her bed at night. As soon as Ms. DeMaio stirs awake, the dog reacts. “She said it gives her a reason to get up in the morning,” Ms. Marasa said.

The dog has been a boon to her, too. “It provides comfort and interaction that I can’t provide every second,” said Ms. Marasa, who lives with her mother but works full time for the county government. “It gives her something that she can feel like is totally her own.”

Advertisement

In Broward County, Fla., where the population of residents over 85 is expected to nearly triple over the next few decades, the local agency on aging has used state and federal money and private grants to provide technologies to nearly 4,000 of the county’s seniors at no cost.

Its offerings include a company that uses radar to sense falls and a program that allows seniors to make video calls through their televisions.

“The possibilities are endless,” Charlotte Mather-Taylor, the agency’s chief executive, said. “It’s pretty great to see all the new technology coming out so quickly, and I think that can only benefit our older population and also our caregivers.”

Even technologies not specifically marketed as age tech can help older adults maintain their independence, said Laurie Orlov, founder of the blog Aging and Health Technology Watch. She pointed to video-calling and telehealth platforms; remotely controlled thermostats and lights; and smart speakers, doorbells and watches.

“All technology can be customized to help older adults stay longer in their homes and help their family members feel good about it, or at least tolerate it,” Ms. Orlov said.

Advertisement

That will only become more true with the continued proliferation of artificial intelligence, Ms. Orlov added. Some older adults are already using conversational A.I. to get answers about things like the weather or their medications. (Relying too heavily on A.I. can, however, have negative consequences because chatbots often give flawed medical advice and can lead patients astray.) A.I. can also assist in pattern detection: alerting caregivers to signals that might indicate declines in someone’s cognition or mental health, such as changing their speech pattern or leaving the house less frequently.

One A.I.-powered age tech tool is ElliQ, a tabletop companion robot that looks like a sleek silver desk lamp with a screen. About a year and a half ago, Camille Wolsonovich got one for free, thanks to a local nonprofit, for her 90-year-old father, Bill Castellano. He lives alone in a senior community.

Ms. Wolsonovich, who runs a consulting business, relies on ElliQ to lead her father in exercises and remind him to take his pills and drink water. The robot also asks her father about his sleep and mood via automated check-ins.

“Everything’s just another layer that gives us more confidence, from a caregiving standpoint, that he’s good,” Ms. Wolsonovich said. “I don’t have to necessarily track everything all the time and be overbearing.”

As for Mr. Castellano? He plays trivia digitally and converses daily with ElliQ. The robot, which has a friendly female voice, asks questions, cracks jokes and remembers his likes, dislikes and friends. “She’s great company,” he said. “Everybody around me wants one.”

Advertisement

Clara Berridge studies the ethics of age tech at the University of Washington.

She has many privacy concerns, namely that most direct-to-consumer products aren’t subject to medical privacy laws, despite being privy to sensitive health information. Though she hopes the federal government will eventually step in to regulate these products, as it has in other countries, the onus remains on the consumer for now.

And even if an age tech product isn’t selling mom’s personal data to the lowest bidder, Dr. Berridge said there’s still the question of whether certain tools are ethical.

“It’s really important for caregivers to recognize that using these new technologies that give them more information about someone can represent greater intrusion into someone’s life,” she said.

What may be well-intentioned monitoring could reveal information that an older adult would rather keep private, such as issues with incontinence, or the comings and goings of a romantic partner.

Advertisement

“It can lead to somebody feeling infantilized,” Dr. Berridge said. “Like there’s not a place to hide within your own home.”

Her research shows that adult children often underestimate how much their parents can understand about technology and how much they want to be involved in tech-related decisions.

She encouraged caregivers to have transparent conversations about privacy implications and to avoid ultimatums or the idea that any decision must be permanent. She said caregivers should put themselves in their parents’ shoes: Is this something they’d want their own children monitoring?

Dr. Berridge is working on an advanced directive for technology, which outlines older people’s wishes for how technology is used in their care. Ultimately, she hopes that questions about age tech will become a standard part of planning for the future.

“If you’re at the start of what, for many people, ends up being a long road of supporting someone potentially through the end of their life,” she said, “seeking to understand each other’s concerns and priorities better is time very well spent.”

Advertisement
Continue Reading
Advertisement

Trending