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Just 5 minutes of exercise could reduce high blood pressure, study finds

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Just 5 minutes of exercise could reduce high blood pressure, study finds

Just a few minutes a day could make a big difference in your blood pressure, according to a new study published in Circulation, the journal of the American Heart Association.

Researchers at University College London (UCL) and the University of Sydney evaluated how small bursts of exercise impacted people’s blood pressure.

A total of 14,761 participants across six countries wore activity trackers while performing short physical tasks, including walking at various speeds, running, cycling or stair climbing, according to a press release from UCL.

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Throughout a 24-hour day, the participants had approximately seven hours of sleep, 10 hours of sedentary behavior (such as sitting), three hours of standing, one hour of slow walking, one hour of fast walking and just 16 minutes of exercise activities, the release stated.

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Just a few minutes a day could make a big difference in your blood pressure, according to a new study published in Circulation, the journal of the American Heart Association. (iStock)

The researchers then analyzed what happened to blood pressure when a person replaced a less active behavior with five minutes of exercise, finding that it resulted in “clinically meaningful” improvements.

Incorporating just 10 to 20 additional minutes of exercise per day could equate to a 10% reduction in heart disease risk, the release stated.

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“Our findings suggest that, for most people, exercise is key to reducing blood pressure, rather than less strenuous forms of movement, such as walking,” Dr. Jo Blodgett, first author of the study from UCL Surgery & Interventional Science and the Institute of Sport, Exercise & Health, said in the release.

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“The good news is that whatever your physical ability, it doesn’t take long to have a positive effect on blood pressure,” she continued. 

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“What’s unique about our exercise variable is that it includes all exercise-like activities, from climbing the stairs to a short cycling errand, many of which can be integrated into daily routines.”

While walking did have some positive effects, the researcher noted, exercises that “put more demand on the cardiovascular system” were shown to be most beneficial for blood pressure.

“When we lead lifestyles our bodies weren’t designed for — such as being sedentary or having constant access to high-calorie foods — our health can suffer.”

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Elevated blood pressure (hypertension) is defined as readings that are consistently above 140/90 mmHg. 

The first number, systolic blood pressure (SBP), measures the pressure against the artery walls when the heart beats, UCL noted. 

The second number, diastolic blood pressure (DBP), measures the pressure against the artery walls while the heart muscle rests between beats.

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The condition affects 1.28 billion adults and is one of the leading causes of death worldwide, statistics show.

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Despite the absence of symptoms, hypertension is a main contributing factor to heart attack, heart failure, stroke, kidney damage and other dangerous conditions.

Elevated blood pressure (hypertension) is defined as readings that are consistently above 140/90 mmHg.  (iStock)

“Previous research in this area has come from heavily controlled exercise training studies with supervised or prescribed exercise programs,” Professor Mark Hamer, joint senior author of the study from UCL Surgery & Interventional Science and the Institute of Sport, Exercise & Health, said in the release.

“The difficulty with these types of studies is that although they work to reduce blood pressure, when people finish the program, they usually revert to their sedentary habits.”

   

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“Our study is unique as we observed free-living physical activity performed in everyday life can have benefits that are most likely far more sustainable long-term.”

This study confirms what clinicians and patients have long observed, according to Ian Del Conde Pozzi, M.D., cardiologist at Miami Cardiac & Vascular Institute.

The human body functions at its best with daily physical activity, a doctor noted. “One way regular exercise reduces cardiovascular risk, including heart disease and stroke, is by lowering blood pressure and improving metabolic health.” (iStock)

“One way regular exercise reduces cardiovascular risk, including heart disease and stroke, is by lowering blood pressure and improving metabolic health, such as enhancing glucose metabolism and supporting healthy weight management,” Del Conde Pozzi, who was not involved in the study, told Fox News Digital.

The human body functions at its best with daily physical activity, the doctor noted.

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“When we lead lifestyles our bodies weren’t designed for — such as being sedentary or having constant access to high-calorie foods — our health can suffer,” he said.

Regular exercise helps restore the body to its “natural state,” allowing it to function better and helping to prevent many chronic health conditions.

Despite the absence of symptoms, hypertension is a main contributing factor to heart attack, heart failure, stroke, kidney damage and other dangerous conditions. (iStock)

Exercise alone may not be enough to resolve hypertension, however.

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“While most patients with high blood pressure may not achieve full blood pressure control through exercise alone, some individuals can potentially prevent high blood pressure altogether by adopting a healthy lifestyle that includes regular exercise,” Del Conde Pozzi said.

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The study was supported by the British Heart Foundation.

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New cancer vaccine delivers stunning result against one of the deadliest skin cancers

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New cancer vaccine delivers stunning result against one of the deadliest skin cancers

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A new injectable therapy is showing positive results in reducing melanoma throughout a five-year period.

The personalized mRNA cancer therapy, called intismeran autogene, combined with the cancer immunotherapy drug KEYTRUDA (pembrolizumab), is a collaboration between Merck and Moderna.

The results from the phase 2b KEYNOTE-942 study were presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on May 27.

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After about a five-year follow-up, the combo drug was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone.

The researchers analyzed data from 157 patients with high-risk stage 3 and 4 melanoma whose cancer had been removed via surgery. The participants were split into two groups — one received the combo therapy and the other only received pembrolizumab, according to a press release.

The therapy was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone after a five-year follow-up. (iStock)

The findings revealed that the combination group saw benefits that were “sustained and durable over time.”

Intismeran autogene is designed using mutations identified in a patient’s own tumor, with the intention of teaching the immune system what the cancer looks like so that it can recognize and attack it.

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According to the researchers, intismeran is “well-tolerated” with a “manageable” safety profile. 

The most commonly cited side effects of the personalized mRNA vaccine plus KEYTRUDA were fatigue, injection-site pain, chills, fever and headache. The researchers reported no new long-term safety concerns and no severe vaccine-related adverse events.

The combination therapy is currently being evaluated in a phase 3 study — the final confirmation stage.

Patients with late-stage melanoma have a “significant risk” of cancer recurrence, according to an expert. (iStock)

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In a Merck press release from January, Kyle Holen, MD, Moderna’s senior vice president and head of development, oncology and therapeutics, noted that this data highlights the “potential of a prolonged benefit … in patients with resected high-risk melanoma.”

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“We continue to invest in our platform in oncology because of encouraging outcomes like these, which illustrate mRNA’s potential in cancer care,” he said.  

Dr. Marjorie Green, senior vice president and head of oncology, global clinical development at Merck Research Laboratories, also commented that for many patients with stage 3 or 4 melanoma, there is a “significant risk of recurrence following surgery.”

Researchers confirmed that the combination therapy is currently being evaluated in a phase 3 study. (iStock)

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“As such, demonstrating the longer-term potential of intismeran autogene and KEYTRUDA to reduce the risk of recurrence for certain patients with melanoma is a meaningful milestone,” she said.

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The company cited encouraging five-year follow-up data and pointed to upcoming late-stage INTerpath trial results with Moderna in several hard-to-treat cancers.

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New ways to prevent flu revealed in ‘accidental’ lab breakthrough, study finds

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New ways to prevent flu revealed in ‘accidental’ lab breakthrough, study finds

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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.

While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.

By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.

5 THINGS YOU NEED TO KNOW BEFORE GETTING YOUR FLU SHOT, ACCORDING TO DOCTORS

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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.

“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.

While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)

While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.

Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.

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“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”

HOW LONG YOU’RE CONTAGIOUS WITH THE FLU — AND WHEN IT’S SAFE TO GO OUT

The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.

The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.

Clinical treatments remain identical for both primary strains of the flu virus. (iStock)

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During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.

RESEARCHERS LOCKED FLU PATIENTS IN A HOTEL WITH HEALTHY ADULTS — NO ONE GOT SICK

The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.

Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.

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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.

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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”

This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)

“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”

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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.

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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.

Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.

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One extra serving of processed meat a day linked to higher cancer risk

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One extra serving of processed meat a day linked to higher cancer risk

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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.

While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.

To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years. 

FREQUENT HEARTBURN MAY BE A WARNING SIGN OF A MORE DANGEROUS CONDITION, DOCTOR SAYS

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The study group included 131,426 men and 318,686 women, according to the study’s press release.

During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.

For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)

Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.

The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.

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BACTERIA IN YOUR MOUTH MAY TRAVEL TO THE GUT AND TRIGGER STOMACH CANCER, RESEARCH FINDS

After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.

A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.

An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)

An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.

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The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.

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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.

The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.

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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.

Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)

Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.

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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.

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The findings were published in the International Journal of Cancer.

Fox News Digital reached out to the researchers requesting comment.

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