Health
Incurable, 'highly contagious' STD affects nearly 900 million people under age 50
The rise of sexually transmitted infections (STIs) continues to pose threats.
The prevalence of one uncurable STI in particular – genital herpes simplex virus (HSV) type 1 and 2 – is at a global high, according to a new study published in the BMJ Journals Sexually Transmitted Infections.
Approximately 846 million people between 15 and 49 years old (more than one in five) were living with a genital herpes infection as of 2020.
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The World Health Organization (WHO) confirmed that at least one person each second, amounting to 42 million people annually, is estimated to acquire the infection.
While HSV-2 is slowly declining, genital HSV-1 is increasing, although it does not cause as much burden, one expert said. (iStock)
The researchers at Weill Cornell Medicine, Qatar, noted that both types of HSV infections are lifelong and can cause symptomatic genital ulcer disease (GUC).
HSV-2 “almost always” causes sexually transmitted genital infection, the researchers said, while HSV-1 mainly causes oral infection, like cold sores, but can be sexually transmitted to cause a genital infection.
The infection can lead to painful genital sores and blisters that typically recur in random episodes throughout life. In 2020, more than 200 million people in the same age group suffered at least one painful symptomatic episode, data shows.
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Not every case of HSV is symptomatic, which makes transmission more likely.
The researchers concluded that the “high incidence and prevalence” of HSV worldwide requires new prevention and treatment measures, such as vaccines, to control the spread and reduce the disease burden.
Approximately 846 million people between 15 and 49 years old are living with a genital herpes infection as of 2020. (iStock)
Study co-author Laith Abu-Raddad, a health care policy and research professor at Weill Cornell Medical College in Qatar, emphasized the scale of HSV’s impact.
“Symptomatic genital herpes imposes a substantial global burden, affecting 200 million people annually and incurring significant economic costs, estimated at $35 billion per year due to health care expenditures and productivity loss,” he wrote in a statement to Fox News Digital.
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“Addressing this pressing health challenge requires a fundamental solution,” Abu-Raddad went on.
“Developing a vaccine capable of protecting against HSV-1 and HSV-2, the viruses responsible for genital herpes, represents a pivotal step toward controlling this infection on a global scale.”
Curing the incurable
There is currently no cure for HSV, although there are treatments to help manage symptoms.
The STI can also lead to more serious complications like neonatal herpes, which can be transmitted from a mother to her baby during childbirth.
HSV-2 accounts for 90% of symptomatic episodes and is linked to a significantly higher risk of contracting HIV, according to the WHO.
HSV can cause painful sores and blisters that can occur in periodic episodes, according to experts. (iStock)
Dr. Gabe Gaviola, senior medical director at Everlywell in New York — an at-home STD testing and treatment platform — shared his concern about increased exposure.
“HSV is highly contagious and often asymptomatic, which means many people may unknowingly transmit the virus,” Gaviola, who was not involved in the study, told Fox News Digital. “This makes prevention and early diagnosis more difficult.”
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“There’s also a persistent stigma associated with genital herpes, which may discourage individuals from seeking treatment or disclosing their herpes status to partners, leading to further spread.”
Gaviola reiterated how HSV infection can increase the risk of contracting other STIs due to the “sores and compromised skin barrier,” which makes it “even more crucial to seek proper testing and treatment.”
“New data in this study highlight just how widespread HSV-2 and HSV-1 are, with millions of new and existing cases each year,” one doctor said. (iStock)
“High prevalence rates, especially in individuals aged 15 to 49 years old, are driven by a lack of public awareness, prevention efforts, and access to testing and treatment,” he said.
For those experiencing symptoms, Gaviola recommends getting regular screenings and being open with sexual partners to reduce the spread.
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“Safer sex practices, including condom use and antiviral treatments for those who have HSV, can help reduce the transmission of HSV,” he added.
While HSV outbreaks can be controlled and potentially become less frequently or severely over time, flare-ups can occur during times of stress or illness, according to Gaviola.
Experts explain that the nature of HSV make it difficult to pinpoint a cure. (iStock)
HSV remains dormant in nerve cells after initial infection, which makes it “extremely difficult to completely eradicate from the body,” he said.
“It can reactivate at any time, often without warning,” he warned. “This dormancy also allows the virus to evade the immune system, which prevents the body from eliminating the infection.”
“It can reactivate at any time, often without warning.”
“While there are no cures yet, progress in vaccine development and antiviral therapies is promising,” he said.
“Public health measures to reduce transmission and improve treatment are critical in managing the global burden of HSV.”
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Anna Wald, M.D., professor of medicine, laboratory medicine and epidemiology at the University of Washington, noted that the nature of the herpes virus, much like chickenpox and shingles, makes the development of a cure difficult – although early, preclinical trials are underway.
According to Wald, there have also been some attempts to develop a preventative HSV vaccine that have failed. (iStock)
“[A] cure is likely to require gene therapy, which is a potentially risky approach for a non-lethal disease,” Wald, who was not involved in the research, told Fox News Digital. “So progress is slow as a result.”
There have also been some attempts to develop a prophylactic vaccine that have failed, according to the doctor.
“Testing vaccines for prevention is very expensive, but there are some new candidate vaccines that will hopefully be in trials in the next few years,” she shared.
“In my opinion, a preventative vaccine would be an optimal approach, but we don’t yet know how to make one that will work – and testing them is a lengthy and costly process.”
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Health
Cancer-linked herbicide in the spotlight after controversial order: ‘Toxic by design’
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There has been a shake-up in the Make America Healthy Again movement regarding glyphosate, a widely used herbicide that has been the subject of significant controversy.
The debate follows an executive order signed by President Donald Trump that ensures an adequate supply of elemental phosphorus and glyphosate-based herbicides related to national defense.
MAHA supporters have previously pushed a pesticide-free agenda, warning of potential health harms caused by glyphosate.
Dr. Marc Siegel, Fox News senior medical analyst, said he believes there is sufficient evidence linking glyphosate to neurodegenerative diseases, including ALS, Parkinson’s and multiple sclerosis, to warrant limiting exposure.
President Donald Trump signed an executive order that ensures an adequate supply of elemental phosphorus and glyphosate-based herbicides related to national defense. (AP Photo/Charlie Neibergall)
“With Parkinson’s, this association appears to be due to the gut, vagus nerve and brain axis, where the exposure affects the microbiome in the gut, which then ascends slowly up to the brain, causing the neurodegenerative disease years later,” Siegel told Fox News Digital.
“There is also a growing association being found between high-dose glyphosate or occupational exposure and metabolic disorders, liver disease and some cancers, specifically lymphoma.”
He added, “Growing research backs this. I favor limiting it.”
“When we apply them across millions of acres and allow them into our food system, we put Americans at risk.”
Studies have shown that glyphosate, which is used in products such as Roundup, owned by Monsanto, could raise cancer risk.
In one University of Washington study published in the journal Mutation Research, researchers found that exposure to it increased the risk of non-Hodgkin lymphoma by 41%.
The nonprofit Investigate Midwest, which analyzed data from both the U.S. Geological Survey and the National Cancer Institute, also recently found that pesticides may contribute to cancer rates.
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Among the top 500 counties for per-square-mile pesticide use, more than 60% had cancer rates above the national average of 460 cases per 100,000 people, according to the report.
Investigate Midwest, which is based in Illinois, interviewed more than 100 farmers, environmentalists, lawmakers and scientists as part of a partnership with the Pulitzer Center’s StoryReach U.S. Fellowship.
Among the top 500 counties for per-square-mile pesticide use, more than 60% had cancer rates above the national average of 460 cases per 100,000 people, according to one study. (iStock)
Iowa, which used 53 million pounds of pesticides last year, holds the nation’s title for second-highest cancer rate.
Bill Billings, a resident of Red Oak, Iowa, was diagnosed with cancer in 2014.
“The cancer specialist said, very directly, (my) cancer is a result of being exposed to chemicals,” Billings said in the report.
Kelly Ryerson, founder of Glyphosate Facts and owner of the Instagram account @glyphosategirl, told Fox News Digital her journey researching the herbicide began with her own health struggles.
Ryerson, who is based in California, previously struggled with chronic illness and autoimmune issues, which she said improved when she stopped eating gluten.
Iowa, which used 53 million pounds of pesticides last year, holds the nation’s title for second-highest cancer rate. (iStock)
After attending a medical conference at Columbia University’s Celiac Disease Center, Ryerson began to question modern farming practices rather than the gluten itself.
“A lot of times, farmers are spraying Roundup on our grains right before harvest to facilitate an easier harvest,” she said. “After that easier harvest, because everything’s dry at the same time, those crops go directly to the mill and may end up in our food supply, at alarmingly high levels.”
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In 2015, the International Agency for Research on Cancer (IARC), part of the World Health Organization framework, classified glyphosate as “probably carcinogenic to humans.”
The classification was based on limited evidence of cancer in humans (notably non-Hodgkin lymphoma in some studies) and sufficient evidence in experimental animals.
“President Trump’s executive order reinforces the critical need for U.S. farmers to have access to essential, domestically produced crop protection tools, such as glyphosate,” a Monsanto spokesperson said. (Wolf von Dewitz/picture alliance via Getty Images)
A spokesperson for Monsanto told Fox News Digital it will comply with Trump’s order to produce glyphosate and elemental phosphorus.
“President Trump’s executive order reinforces the critical need for U.S. farmers to have access to essential, domestically produced crop protection tools, such as glyphosate,” the spokesperson said.
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HHS Secretary Robert F. Kennedy Jr. has long been a vocal critic of Roundup, working with his legal team in 2018 to award $289 million to a man who alleged the weed killer caused his non-Hodgkin lymphoma, according to reports.
Following backlash to Trump’s executive order, Kennedy said he supports the order but acknowledged that “pesticides and herbicides are toxic by design, engineered to kill living organisms.”
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“When we apply them across millions of acres and allow them into our food system, we put Americans at risk,” he posted on X. “Chemical manufacturers have paid tens of billions of dollars to settle cancer claims linked to their products, and many agricultural communities report elevated cancer rates and chronic disease.”
Fox News Digital reached out to the White House for comment.
Health
Common nighttime noise exposure may trigger heart problems, study suggests
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Living near heavy traffic could negatively impact your heart health.
A European study, published in the journal Environmental Research, found that exposure to nighttime road traffic noise is linked to changes in the blood, leading to worsened cholesterol and cardiovascular risks.
The researchers considered data from the U.K. Biobank, Rotterdam Study, and Northern Finland Birth Cohort 1966, including more than 272,000 adults over the age of 30, according to a press release.
Nighttime road noise exposure was estimated at all participants’ homes based on national noise maps. Researchers also took blood samples to measure the participants’ metabolic biomarkers for disease, then mapped the link between nightly noise levels and existence of biomarkers.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers. (iStock)
The study found that people exposed to louder noise at night — especially sounds above 55 decibels — showed changes in 48 different substances in their blood. Twenty of these associations “remained robust” throughout all cohorts.
Exposure to loud noise was associated with increased concentrations of cholesterol-related biomarkers, especially LDL “bad” cholesterol, IDL (intermediate-density lipoprotein) and unsaturated fatty acids.
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As noise levels increased, starting at around 50 decibels, cholesterol markers rose steadily, the release stated.
The authors concluded that this study “provides evidence that nighttime road traffic noise exposure from 50 dB upward is associated with alterations in blood cholesterol and lipid profiles in adults.”
Researchers noted a link between traffic noise and cardiometabolic disease. (iStock)
Study co-author Yiyan He, doctoral researcher at the University of Oulu in Finland, noted that in this type of research, small effect sizes are expected, and environmental exposures such as traffic noise are “typically modest.”
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“Despite this, we observed statistically robust and consistent associations across many biomarkers, especially those related to LDL and IDL lipoproteins,” she told Fox News Digital.
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“We also identified a clear exposure-response pattern starting at around 50 dB, suggesting that metabolic changes become more evident as noise levels increase.”
This aligns with public health guidance, as the World Health Organization recommends lower nighttime noise limits at around 40 to 45 dB, Yiyan He added.
“This finding may clarify the association between traffic noise and cardiometabolic diseases,” the researchers wrote. (iStock)
“The 55 dB level is often used as an interim benchmark associated with substantial noise annoyance and sleep disturbance,” she said. “In our study, we observed associations not only at 55 dB, but also indications of effects emerging at around 50 dB.”
The strength and consistency of the cholesterol-related associations were surprising, as these changes are usually “subtle.”
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“Instead, we found consistent associations across multiple large European cohorts, which strengthens confidence that the findings may reflect real biological patterns,” Yiyan He went on. “We were also interested to see that effects were minimal below ~50 dB, suggesting a possible threshold-like pattern.”
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The researcher noted that these findings were consistent across genders, education levels and obesity status.
The study was restricted to White Europeans, which posed a limitation. There was also a lack of information on the fasting status in the UK Biobank.
Changes in cholesterol levels were more severe than researchers expected. (iStock)
“Fasting can influence levels of certain metabolites, particularly fatty acids,” Yiyan He said. “However, based on UK Biobank documentation, fewer than 10% of participants were fasting for at least eight hours, and our main findings focused on cholesterol-related biomarkers, which are generally less sensitive to short-term fasting.”
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The researchers also lacked information on bedroom location, indoor noise exposure and time spent at home.
“These factors may introduce non-differential exposure misclassification,” Yiyan He said. “Additionally, noise exposure estimates were based on participants’ temporary residential addresses at the time of blood sampling, without considering the duration of residence.”
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“Many of these limitations would tend to bias results toward the null, so the consistent associations we observed remain noteworthy.”
Experts recommend taking measures to limit traffic noise at night. (iStock)
Based on this latest research, Yiyan He noted that nighttime noise is a “health-relevant exposure,” not just “an annoyance.”
“Our findings suggest that nighttime traffic noise may subtly but consistently affect metabolic health,” she said. “While the changes in cholesterol and lipid levels for any one individual are small, traffic noise affects a very large number of people, which means the potential public health impact could be substantial.”
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The researcher recommends taking measures like improving sound insulation, using noise-reducing strategies and placing bedrooms on the quieter side of the home when possible.
“Because sleep is a key pathway linking noise to health, protecting the nighttime sleep environment is especially important,” she added.
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