Health
Dementia risk could increase with low levels of essential vitamin
“Normal” levels of vitamin B12 may not be enough to ward off dementia, new research finds.
Researchers at University of California San Francisco studied 231 healthy older adults (averaging 71 years of age) who did not have dementia or mild cognitive impairment.
Blood tests showed that their B12 levels averaged 414.8 pmol/L, while the recommended minimum level in the U.S. is just 148 pmol/L.
DRUGS THAT REDUCE DEMENTIA RISK — AND OTHERS THAT INCREASE IT
Participants who had lower B12 levels were found to have “slower cognitive and visual processing speeds” when taking tests, which is linked to “subtle cognitive decline,” according to a UCSF press release.
The effect was more pronounced with age.
“Normal” levels of vitamin B12 may not be enough to ward off dementia, new research finds. (iStock)
The people with lower levels also had more lesions in the white matter in their brains, which can be a warning sign of cognitive decline, dementia or stroke, the researchers found.
The findings were published in Annals of Neurology on Feb. 10.
Based on these results, the researchers recommend updating the current B12 requirements.
DEMENTIA RISK COULD BE LOWERED BY DOING THIS FOR 5 MINUTES A DAY: STUDY
“Previous studies that defined healthy amounts of B12 may have missed subtle functional manifestations of high or low levels that can affect people without causing overt symptoms,” said senior author Ari J. Green, MD, of the UCSF Departments of Neurology and Ophthalmology and the Weill Institute for Neurosciences.
“Revisiting the definition of B12 deficiency to incorporate functional biomarkers could lead to earlier intervention and prevention of cognitive decline.”
“Revisiting the definition of B12 deficiency to incorporate functional biomarkers could lead to earlier intervention and prevention of cognitive decline.” (iStock)
The researchers did acknowledge that the study only included older adults, who may have a “specific vulnerability” to lower levels of B12.
Those lower levels, however, “could impact cognition to a greater extent than what we previously thought, and may affect a much larger proportion of the population than we realize,” according to co-first author Alexandra Beaudry-Richard, who is currently completing her doctorate in research and medicine at the UCSF Department of Neurology and the Department of Microbiology and Immunology at the University of Ottawa.
TWO ALZHEIMER’S DRUGS HELP PATIENTS LIVE INDEPENDENTLY AT HOME FOR LONGER PERIODS
“In addition to redefining B12 deficiency, clinicians should consider supplementation in older patients with neurological symptoms even if their levels are within normal limits,” she suggested in the release.
“Ultimately, we need to invest in more research about the underlying biology of B12 insufficiency, since it may be a preventable cause of cognitive decline.”
“Even participants with B12 levels deemed ‘normal’ by today’s medical standards showed clear signs of neurological impairment.”
Dr. Brett Osborn, a Florida neurosurgeon and longevity expert, said the study supports the idea that “normal” vitamin B12 levels are “grossly inadequate” for protecting the brain from age-related decline.
“Even participants with B12 levels deemed ‘normal’ by today’s medical standards showed clear signs of neurological impairment — slower processing speeds, increased white matter hyperintensities on MRI (a marker of small vessel disease), and elevated tau protein (a biomarker of neurodegeneration). This is concerning to say the least,” Osborn told Fox News Digital.
The current minimum recommendations weren’t designed for optimal cognitive function or longevity, according to Osborn.
One neurosurgeon and longevity expert recommends supplements of B-complex vitamins, including B12, to ensure healthy levels of homocysteine, an amino acid that is produced during protein metabolism. (iStock)
“Instead, they were based on population averages — an inherently flawed approach when the ‘average’ person today is metabolically unhealthy. This is yet another example of mainstream medicine lagging behind the science.”
In Osborn’s clinic, he recommends supplements of B-complex vitamins, including B12, to ensure healthy levels of homocysteine, an amino acid that is produced during protein metabolism.
DOES EVERYONE NEED TO TAKE VITAMINS — AND WHICH ARE MOST IMPORTANT? HERE’S WHAT TO KNOW
“When homocysteine is elevated — a potential proxy for low B12 — brain function declines,” Osborn said.
The doctor did note that the study is observational, and that “correlation doesn’t prove causation.”
“Even participants with B12 levels deemed ‘normal’ by today’s medical standards showed clear signs of neurological impairment.” (iStock)
“But do you really need a randomized controlled trial to tell you that optimizing B12 intake benefits brain health? That’s like waiting for a study to confirm that eating vegetables is good for you,” Osborn said.
“The data are there. The science is crystal-clear.”
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
Like the researchers, Osborn called for an update to the “normal” lab levels.
“It’s time to start defining health by optimal levels — not by whatever happens to be ‘average’ in an increasingly sick population. Because who wants to be normal when you can be optimal?”
“No clear evidence has been found to suggest benefit in B12 supplementation in patients without a deficiency.”
Dr. Earnest Lee Murray, a board-certified neurologist at Jackson-Madison County General Hospital in Jackson, Tennessee, agreed that this study raises the question of redefining what levels constitute a B12 deficiency.
“Previous studies have recommended supplementation in patients with a known vitamin B12 deficiency to mitigate cognitive issues; however, no clear evidence has been found to suggest benefit in B12 supplementation in patients without a deficiency,” Murray, who was not involved in the study, told Fox News Digital.
The neurologist cautioned against people taking “mega-doses” of vitamins.
For more Health articles, visit www.foxnews.com/health
“Often, high levels of vitamins, especially B12, won’t cause issues; however, it can happen,” Murray said.
“I would recommend that patients who are older or at risk of developing cognitive decline discuss with their physician about being tested — not just for vitamin B12 levels, but also for other markers that could suggest improper absorption of vitamin B12.”
Health
Healthy diets spark lung cancer risk in non-smokers as pesticides loom
NEWYou can now listen to Fox News articles!
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests.
The observational study, led by Jorge Nieva, M.D., of the USC Norris Comprehensive Cancer Center at Keck Medicine, was presented this month at the American Association for Cancer Research (AACR) annual meeting in San Diego. It has not yet been peer-reviewed.
Researchers looked at dietary, smoking and demographic data for 187 patients who were diagnosed with lung cancer at age 50 or younger.
PANCREATIC CANCER PATIENT SURVIVAL DOUBLED WITH HIGH DOSE OF COMMON VITAMIN, STUDY FINDS
They found that among non-smokers, there was a link between healthier-than-average diets – rich in fruits, vegetables and whole grains – and the chance of lung cancer development.
Young lung cancer patients ate more servings of dark green vegetables, legumes and whole grains compared to the average U.S. adult, the researchers found.
Eating a diet high in fruits and vegetables was found to have a surprising link to lung cancer among younger non-smokers, early research suggests. (iStock)
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association.
“Commercially produced (non-organic) fruits, vegetables and whole grains are more likely to be associated with a higher residue of pesticides than dairy, meat and many processed foods,” according to Nieva. He also noted that agricultural workers exposed to pesticides tend to have higher rates of lung cancer.
HIDDEN VIRUS INSIDE GUT BACTERIA LINKED TO DOUBLED COLORECTAL CANCER RISK, STUDY FINDS
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” Nieva told Fox News Digital.
The disease is becoming more common in non-smokers 50 and younger, especially women – despite the fact that smoking rates have been falling for decades, the researcher noted.
The researchers hypothesized that pesticides applied to conventionally grown produce could be a possible factor in the disease association. (iStock)
“These patients tend to have eaten much healthier diets before their diagnosis than the average American,” he went on. “We need to support research into understanding why Americans – and women in particular – who no longer smoke very much are still having lung cancer,” he said.
DEATHS FROM ONE TYPE OF CANCER ARE SURGING AMONG YOUNGER ADULTS WITHOUT COLLEGE DEGREES
The study did have some limitations, Nieva acknowledged, primarily that it relied on survey data and was limited by the participants’ memories of their food intake.
“Also, the survey participants were self-selected, and this could have biased the findings,” he told Fox News Digital.
“There is a large subset of lung cancer patients whose disease is not caused by smoking.”
The researchers did not test specific foods for pesticides, relying instead on average pesticide levels for certain types of food. Looking ahead, they plan to test patients’ blood and urine samples to directly measure pesticide levels, Nieva said.
Although the study shows only an association and does not prove that pesticides caused lung cancer, Nieva recommends that people wash their produce before eating and choose organic foods whenever possible.
CLICK HERE FOR MORE HEALTH STORIES
“This work represents a critical step toward identifying modifiable environmental factors that may contribute to lung cancer in young adults,” said Nieva. “Our hope is that these insights can guide both public health recommendations and future investigation into lung cancer prevention.”
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but is by no means certain,” a doctor said. (AP Photo/Charlie Neibergall)
Dr. Marc Siegel, Fox News senior medical analyst, said the study is “interesting,” but that it “raises far more questions than it answers.”
“It is a small study (around 150) and observational, so no proof,” the doctor, who was not involved in the research, told Fox News Digital.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
“It is possible that the increased lung cancer risk could be due to pesticide exposure in whole farmed foods, but it is by no means certain,” Siegel went on. “How much exposure is needed? How much of it gets into food and in which areas? This requires much further study.”
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
Kayla Nichols, communications director for Pesticide Action & Agroecology Network, a distributed global network, said the organization agrees with the study’s conclusion that more research should be done on the rise in lung cancer, particularly in individuals eating diets higher in produce and fiber.
“There is a large subset of lung cancer patients whose disease is not caused by smoking,” the researcher told Fox News Digital. (iStock)
“There is a bounty of existing research that already links pesticide exposure to increased risk of multiple types of cancers,” Nichols, who was also not involved in the study, told Fox News Digital. She called for more research on chronic, low-level exposures to pesticides, as well as more effective policies to protect the public from pesticide residues on food.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
The study was supported by the National Institutes of Health and the National Cancer Institute, as well as industry partners including AstraZeneca and Genentech, among others.
Fox News Digital reached out to several pesticide companies and trade groups for comment.
Health
Deaths from one type of cancer are surging among younger adults without college degrees
NEWYou can now listen to Fox News articles!
Colorectal cancer, once considered a disease of older age, is becoming a crisis for younger adults. New research shows one group getting hit the hardest – those without a college degree.
A recent study from the American Cancer Society analyzed data from over 101,000 adults aged 25 to 49 who died from colorectal cancer between 1994 and 2023.
While death rates remained stable for college graduates, they climbed significantly for those without a bachelor’s degree, the findings showed.
WIDESPREAD HABIT MAY RAISE COLORECTAL CANCER RISK MORE THAN YOU THINK
For young adults with a high school education or less, the mortality rate rose from 4.0 to 5.2 per 100,000 people, while the rate for those with at least a bachelor’s degree stayed flat, at approximately 2.7 per 100,000.
This does not mean that a degree offers some kind of biological protection, researchers cautioned.
Colorectal cancer, once considered a disease of older age, is becoming a crisis for younger adults. (iStock)
The difference is likely driven by the conditions in which people live and work, which often correlate with education levels, the researchers noted.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
The study suggests that the higher death rates are likely driven by differences in the prevalence of risk factors, including obesity, physical inactivity, smoking and diet, which are “known to be elevated among children and young adults with lower [socioeconomic status].”
Because the study relied on death certificates, researchers couldn’t say exactly why college graduates had better outcomes.
Because the researchers didn’t have the patients’ actual medical records, they couldn’t see things like frequency of screenings or treatment options, which would impact survival outcomes. (iStock)
Certificates typically list the cause of death, age, race and education level, but they do not include a person’s full medical history.
RED FLAGS FOR COLORECTAL CANCER THAT WARRANT SCREENINGS BEFORE 45 YEARS OF AGE
Because the researchers didn’t have the patients’ actual medical records, they couldn’t see things like frequency of screenings or treatment options, which would impact survival outcomes.
CLICK HERE FOR MORE HEALTH STORIES
Colorectal cancer is now the leading cause of cancer death for men under 50 and the second leading cause for women in the same age group, according to recent statistics.
While colorectal cancer death rates remained stable for college graduates, they climbed significantly for those without a bachelor’s degree, the findings showed. (iStock)
Because the disease is highly treatable when caught early, the U.S. Preventive Services Task Force (USPSTF) lowered the recommended screening age from 50 to 45 in 2021.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
Common signs and symptoms of colorectal cancer can include a change in bowel habits, such as diarrhea, constipation or narrowing of the stool, that lasts for more than a few days, according to the American Cancer Society.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
Other signs that warrant seeing a doctor include blood in the stool or a persistent feeling of needing to go to the bathroom but being unable to go.
The research was published in JAMA Oncology.
Health
Cancer tied to woman’s vaping habit since age 15 as she’s now given just months to live
NEWYou can now listen to Fox News articles!
A young woman who started vaping at the age of 15 has been given just 18 months to live — after being diagnosed with lung cancer in her early 20s.
Kayley Boda, 22, of Manchester, in the United Kingdom, was engaging in heavy vaping on a regular basis when she started coughing up a brown substance with “grainy bits” in it in January 2025, news agency SWNS reported.
The retail assistant said doctors turned her away eight times, telling her she had a chest infection — until she began coughing up blood.
SMOKING AND VAPING MAY BE BANNED AT ONE STATE’S MOST POPULAR BEACHES AND PARKS: HERE’S WHY
After seven biopsies, Boda was diagnosed with lung cancer. She underwent surgery to remove the lower lobe of her right lung, as well as chemotherapy — and in February 2026, got the all-clear, the same source reported.
Two months later, though, doctors said the cancer had come back in the pleural lining. Now she’s been given 18 months to live.
Kayley Boda, 22, is shown in the hospital. She started coughing up a brown substance with “grainy bits” in January 2025, she said. She had been vaping since the age of 15. (SWNS)
The young woman has now issued a warning to others to be aware of the dangers of vaping.
Boda said she smoked a bit as a young teenager. She took up vaping after that.
Then, “a few months after I switched from reusable vapes to disposable ones, I started coughing up brown, grainy mucus,” as SWNS reported.
TOURISTS MAY FACE STEEP FINES AND JAIL TIME FOR VAPES AT THIS VACATION HOT SPOT
“Doctors turned me away eight times with a chest infection. … Then I started coughing up blood, so they did an X-ray and found a shadow on my lung,” she added.
“They told me they were 99% sure, [since I was] so young, that it wasn’t cancer, so not to worry about it. When I got the results back, and they told me it was lung cancer, it felt so surreal.”
Boda said she was “very naive” before her diagnosis and thought that “something like this would never happen to me.”
She said that she had surgery to remove half of her right lung.
“After the surgery, I started chemo and I had a terrible reaction to it. I couldn’t lift my head up. I was throwing up blood. I was urinating blood. I couldn’t eat. I couldn’t sleep.”
VACATION HOT SPOT CRACKS DOWN ON VAPING WITH JAIL THREATS AND HEFTY FINES
She said that when she got the “all clear [in Feb. 2026], it felt amazing, but just two months later I was told the cancer had come back, and I have 18 months to live.”
She added, “I’m 22. This isn’t meant to happen to somebody my age.”
“Stay off the vapes because they will catch up with you.”
She blames her cancer on vaping, she said.
“My symptoms started a few months after I started disposable vapes, and there’s no lung cancer in my family,” she said. “I haven’t vaped for three months, I’ve made my partner stop, I’ve made my mom stop, I’m urging all my friends to stop. Stay off the vapes,” she continued, “because they will catch up with you.”
When doctors did an X-ray, they found a shadow on Boda’s right lung. She was later diagnosed with lung cancer and has undergone surgery to remove the lower lobe of her right lung, as well as chemotherapy. (SWNS)
She said she’d been using reusable vapes since the age of 15 and began using disposable vapes a few months before her cancer symptoms started.
DISPOSABLE VAPES MORE TOXIC AND CARCINOGENIC THAN CIGARETTES, STUDY SHOWS
In November 2024, when she developed a rash all over her body, doctors said it could have been due to shingles, chicken pox or scabies, she told SWNS.
‘Nothing worked’
“I got treated for all three, and nothing worked,” Boda said. “It got to the point where I was cutting myself from scratching so hard.”
A few months after that, she began coughing up a dark brown mucus, with “grainy bits, the consistency of sugar, in it,” she said. When the coughing continued, she visited the doctor’s office, but was told it could be scarring from pneumonia or a chest infection, she also said.
CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER
It wasn’t until March 2025 that she began coughing up bright red blood. At that point, doctors gave her a chest X-ray and told her they’d found a shadow on her lower right lung.
Over the next four months, she had seven biopsies as doctors took samples from the “shadow.” In August, when she went to get the results, she was told she had stage one lung cancer.
Boda is shown in the hospital. She was diagnosed with lung cancer and had surgery to remove the lower lobe of her right lung, as well as chemotherapy. (SWNS)
In September 2025, she had surgery to remove the lower lobe of her right lung, and the surrounding lymph nodes. During the surgery, doctors upstaged her cancer from stage one to stage three after finding cancer in six surrounding lymph nodes, she said.
Following the surgery, Boda was unable to breathe properly and had to learn to walk all over again.
“The oncologist said this is so rare.”
After finishing chemotherapy in February 2026, Kayley was given the all clear, leaving her feeling elated.
TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ
However, just a month after that, she began experiencing extreme chest pains and was told by doctors she had a pleural effusion — a build-up of fluid in the lungs. She had the fluid removed, but when doctors tested it, they discovered her cancer had returned to the pleural lining of her lungs, giving her 18 months to live.
“The oncologist said this is so rare, and usually something they see in patients that are 80 years old,” she said, as SWNS reported.
Increasingly, vacation hot spots are enforcing strict bans on the use of e-cigarettes in public venues. (iStock)
Boda claimed that doctors were unable to pin her cancer to a specific cause — but told her that smoking and vaping definitely didn’t help.
Since her diagnosis, she has stopped and is urging others to stop, too.
CLICK HERE TO DOWNLOAD THE FOX NEWS APP
She’s hoping to raise the thousands of dollars needed for treatment to try to prolong her life, she said.
Last year, Fox News Digital reported on the case of a Pennsylvania woman, 26, who said she vaped for just one year before her lungs collapsed. She was 22 when she took up the habit, she said in an interview.
“Everybody warned me about it, but I didn’t listen — I wish that I did,” she said.
CLICK HERE FOR MORE HEALTH ARTICLES
Dr. David Campbell, clinical director and program director at Recover Together Bend in Oregon, told Fox News Digital at that time that signs of collapsed lungs include sharp chest or shoulder pain, shortness of breath and difficulty breathing.
Lung issues are just one of the many health issues linked to vaping, he warned. The habit can also increase the risk of heart disease and stroke, as well as exposure to harmful heavy metals.
Melissa Rudy of Fox News Digital contributed reporting.
-
New York4 minutes agoN.Y.P.D. Narcotics Unit Under Review After a Beating Is Caught on Tape
-
Detroit, MI34 minutes agoMI Healthy Climate Conference in Detroit focuses on green funding and strong future
-
San Francisco, CA46 minutes agoCalifornia’s New Hotel Edit: The Best Places to Stay Across the Golden State in 2026
-
Dallas, TX52 minutes agoThe Brandon Aubrey Deal | DZTV
-
Miami, FL58 minutes agoRanking the Miami Heat’s Top Trade Targets
-
Boston, MA1 hour agoFormer Massachusetts doctor faces 81 new sexual assault charges
-
Denver, CO1 hour agoHouston County murder suspect returns to face charges after her arrest in Denver
-
Seattle, WA1 hour agoWest Seattle Tool Library to host annual tool sale this Saturday, April 25 | The White Center Blog