Health
COVID-19 virus could attack cancer cells and shrink tumors, new study suggests
COVID-19 can cause a long list of health issues, including flu symptoms, respiratory problems and even organ damage, according to medical experts — but a new study suggests that the virus could have a surprising impact on cancer.
The study, which was published in the Journal of Clinical Investigation on Friday, found that COVID infection was linked to cancer regression, which could serve as a foundation for new cancer treatments in the future.
The SARS-CoV-2 virus — which causes COVID — is made up of RNA (ribonucleic acid), a molecule that is found in all living cells.
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In the study, RNA was found to “trigger the development of a unique type of immune cell with anti-cancer properties,” according to a press release from the Northwestern Medicine Canning Thoracic Institute in Chicago.
Dr. Ankit Bharat’s research team is pictured at the Northwestern Medicine lab. (Northwestern Medicine)
The newly created immune cells were able to move into the blood vessels and tumors — something typical immune cells cannot do.
“These killer cells then swarm the tumor and start attacking the cancer cells directly, helping to shrink the tumor,” noted senior author Ankit Bharat, MD, chief of thoracic surgery at Northwestern Medicine, in the release.
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This effect was activated by severe COVID-19, the researchers found, and was specifically seen to be effective against melanoma, lung cancer, breast cancer and colon cancer.
“This discovery opens up a new avenue for cancer treatment,” Bharat said in the release.
“It offers hope that we might be able to use this approach to benefit patients with advanced cancers who have not responded to other treatments.”
Early findings warrant more research
This finding has so far only been seen in animal models.
“We are in the early stages, but the potential to transform cancer treatment is there,” Bharat said in the release.
“Our next steps will involve clinical trials to see if we can safely and effectively use these findings to help cancer patients,” the study author said. (iStock)
“Our next steps will involve clinical trials to see if we can safely and effectively use these findings to help cancer patients.”
“The presumed mechanism is that a major inflammation event like an infection can tip the scales toward activating the immune system against a cancer.”
Dr. Marc Siegel, clinical professor of medicine at NYU Langone Health and senior medical analyst for Fox News, pointed out that while this is “not a cancer cure and was only seen in mice,” the study does have some significance.
“It reminds us that viruses cause inflammation and rev up the immune system, which can either increase your risk of certain cancers or, paradoxically, cause certain cancers to shrink by activating immune cells against them,” Siegel, who was not involved in the study, told Fox News Digital.
Dr. Jacob Glanville, CEO of Centivax, a San Francisco biotechnology company, also was not involved in the study but said he wasn’t surprised by the findings.
“There’s a known history of this phenomenon of ‘spontaneous regression’ following an infection with a high fever in multiple illnesses, dating back as far as doctors have been identifying cancer,” he told Fox News Digital.
In the study, RNA was found to “trigger the development of a unique type of immune cell with anti-cancer properties,” according to a press release. (Northwestern Medicine)
“Normally, the immune system can tell there’s something wrong with cancerous tissue, but cancers develop various mutations to hold the immune system back from attacking them,” Glanville went on.
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“The presumed mechanism is that a major inflammation event like an infection can tip the scales toward activating the immune system against cancer.”
The Northwestern Medicine building is pictured in Chicago, Illinois. (Northwestern Medicine)
Studies have shown that COVID-19 vaccines could have the same effect, he added, but it’s likely more common for an actual infection to cause this, as the immune system is more “riled up” by the infection.
Even so, Glanville added, “The rate of this happening likely isn’t yet high enough to justify it as a reliable therapy.”
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The study was funded by the National Institutes of Health and Canning Thoracic Institute.
Fox News Digital reached out to the researchers for additional comment.
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Journalist Katie Couric is sharing a scary medical episode that she experienced on June 27.
In a post on Substack titled “The Day I’ll Never Remember,” she detailed a sudden episode that left her unable to recall the current month, year and president.
“I thought it was 2024. And I believed Joe Biden was president,” she wrote.
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The event occurred while Couric was attending the Aspen Ideas Festival in Colorado, during which she participated in two public panels — one on AI and one on journalism — both of which she cannot remember at all.
“I have no idea what we talked about, or of what occurred when the panels ended,” she said.
Journalist Katie Couric is sharing a scary medical episode that she experienced on June 27. (Getty Images)
John Molner — Couric’s husband, who was in attendance at the festival and the two panels — also shared his account.
After the event, someone told Molner that Katie wasn’t feeling well. When he reached her, an EMT and a doctor were tending to her. “I could tell something was off,” he wrote. “It could have been altitude sickness, but Katie was definitely not all there.”
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At the hospital, when Couric struggled to recall the year, the president and her grandchildren’s names, doctors began checking for a stroke.
An MRI revealed no signs of stroke, which was a relief, but “Katie’s ‘fog’ became a lot more apparent,” Molner wrote.
John Molner, Couric’s husband, who was in attendance at the festival and the two panels, also shared his account. (Getty Images)
“She repeatedly asked me the same questions: ‘What was I doing before we got to the hospital?’ ‘Why am I at the hospital?’”
Couric was ultimately diagnosed with transient global amnesia, a sudden, temporary episode of memory loss that prevents a person from forming new memories and may also erase some recent memories, according to Mayo Clinic.
“The cause seems to be as mysterious as the brain itself.”
It is not caused by a stroke, seizure or head injury, and it usually resolves completely within 24 hours.
“[It’s] just a very weird neural episode that’s pretty uncommon and, at least in most cases, is a ‘one and done’ experience,” Molner said.
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Couric said she finally began feeling “like herself” again around 9 p.m. and went to sleep at 2 a.m.
As TGA leaves a “permanent gap in memory” for the duration of the episode and for hours beforehand, Couric said that from around noon on that day until at least 7 p.m. will remain a “big, black hole.”
As TGA leaves a “permanent gap in memory” for the duration of the episode and for hours beforehand, Couric said that from around noon on that day until at least 7 p.m. will remain a “big, black hole.” (Getty Images)
Data shows that approximately three to eight people per 100,000 will have an episode of transient global amnesia, with people 50 years of age and older at higher risk.
The specific cause of TGA is not known, but some experts believe it stems from a “temporary dysfunction in the brain’s hippocampus — the area responsible for creating new memories,” Couric shared.
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“Doctors believe this is driven by brief interruptions in blood or oxygen flow, or microscopic spasm in the blood vessels.”
Episodes could potentially be triggered by intense physical exertion, emotional distress, extreme temperature changes or migraines, experts say.
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Approximately 15% of patients will have a recurrence 10 years later.
“Why did this happen to me? Was the altitude an issue? Was I dehydrated? Tired? Stressed? The literature doesn’t seem to indicate that these are contributing factors, but the cause seems to be as mysterious as the brain itself,” Couric wrote.
Anyone who experiences sudden memory loss, confusion, difficulty speaking, weakness, numbness, vision changes, severe headache or other stroke-like symptoms should seek immediate medical attention or call 911, doctors advise. (iStock)
“All I know is that those hours will be forever lost. Someone described it as my brain failing to hit the ‘record button.’”
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“While this was a freaky occurrence, it could have been much more serious. So ultimately, I’m relieved — even though several hours of a Saturday in June will always be missing for me.”
Anyone who experiences sudden memory loss, confusion, difficulty speaking, weakness, numbness, vision changes, severe headache or other stroke-like symptoms should seek immediate medical attention or call 911, doctors advise.
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Older adults identified as “super movers” are about half as likely to develop cognitive impairment than their peers.
That’s according to a recent study led by Stony Brook Medicine in New York, which evaluated the cognitive function of 4,000 adults 80 and over who participated in multiple aging and longevity studies over several years.
Among this group, 6% to 10% were classified as super movers, which means they walk at a much faster pace than others of the same age and gender — at speeds comparable to people three decades younger.
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The super movers were found to have about half the risk of cognitive decline compared to seniors with typical gait speed.
The findings were published in the journal Neurology on June 16.
Older adults identified as “super movers” are about half as likely to develop cognitive impairment than their peers. (iStock)
“The study reinforces that mobility and brain health are closely connected,” lead study author Dr. Joe Verghese, MD, neurologist at Stony Brook Medicine, told Fox News Digital. “This suggests that preserving mobility may be an important marker of healthy brain aging and resilience.”
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The most intriguing finding, according to Verghese, was that super movers maintained cognitive function despite having similar dementia-related brain changes as their peers.
In postmortem brain analysis, there was no difference in dementia-related pathologies between the super movers and the slower walkers, the study stated.
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“This suggests they may possess resilience mechanisms that help preserve brain function even in the presence of age-related changes,” he said. “Understanding these resilience factors could lead to new strategies for promoting healthy brain aging.”
As the study was observational, there were some limitations, and it does not prove that walking faster prevents dementia, the researchers noted.
Super movers were found to have about half the risk of cognitive decline compared to seniors with typical gait speed. (iStock)
“Other factors, such as cardiovascular health, physical fitness or genetics, may also contribute to both faster walking and better cognitive outcomes,” Verghese said.
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This study adds to growing evidence that what’s good for the heart and muscles also benefits the brain, he noted, adding that “staying physically active remains one of the most effective, evidence-based ways to support healthy aging.”
“Walking speed is best viewed as a marker of overall health, not a treatment.”
“The broader message is that physical activity is important at any age,” Verghese said. “Walking is an easy step-up point because you don’t need any special equipment. You can do it inside or outdoors, and you can do it on a regular basis. You can walk with a dog, you can walk with a friend.”
Any activity is beneficial if it’s done regularly and with the right intensity, he added.
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Rather than just trying to walk faster, the neurologist recommends that seniors focus on maintaining mobility through regular physical activity, strength training, balance exercises and good cardiovascular health.
“Walking speed is best viewed as a marker of overall health, not a treatment,” Verghese noted.
Major public health guidelines from the CDC and U.S. Physical Activity Guidelines recommend at least 150 minutes of moderate-intensity aerobic activity each week, such as brisk walking.
Major public health guidelines from the CDC and U.S. Physical Activity Guidelines recommend at least 150 minutes of moderate-intensity aerobic activity each week, such as brisk walking. (iStock)
This can be achieved by walking 30 minutes a day, five days a week, or about 20 to 25 minutes most days. Another option is to engage in shorter sessions that add up over the day.
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“You have to do it within your health limitations and medical conditions,” Verghese advised. “So if there are any medical concerns, I would get your physician to clear you before starting exercise.” The good thing about walking, he added, is that you can start at a slow pace and then gradually build up to a brisker pace.
“And then adding on strength and balance training, whatever age you are, I think is also important.”
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