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Colorectal cancer risk reduced by this common vitamin, study suggests

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Colorectal cancer risk reduced by this common vitamin, study suggests

Vitamin D is widely known for boosting bone health, muscle strength and immune function, but it also has a range of other benefits — including cancer prevention.

A new study published in the journal Nutrients suggests that the common vitamin is effective in preventing and treating colorectal cancer.

Hungarian researchers conducted a meta-analysis of 50 previous studies that included more than 1.3 million participants, focusing on vitamin D’s potential effects on cancer risk, immunity and inflammation.

COMMON VITAMIN SHOWN TO REDUCE AUTOIMMUNE DISEASE

“The most important finding is that vitamin D plays a critical role in the prevention and treatment of colorectal cancer,” study author János Tamás Varga, PhD, associate professor at Semmelweis University in Budapest, told Fox News Digital.

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Vitamin D is widely known for boosting bone health, muscle strength and immune function, but it also has a range of other benefits — including cancer prevention. (iStock)

“Our research clearly supports the strong correlation between 25-hydroxyvitamin D (the primary form of vitamin D) levels and cancer outcomes.”

Cancer patients with low vitamin D levels showed poorer prognoses.

Vitamin D has been shown to reduce inflammation, promote the death of cancer cells, inhibit tumor growth and enhance immune response, the researchers found. 

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“These mechanisms significantly influence the pathophysiology of colorectal cancer,” Varga noted. 

In addition to prevention, vitamin D supplementation was also shown to improve survival rates among patients with advanced-stage colorectal cancer, according to the research.

“The results suggest that the effect of vitamin D may depend on factors such as the dosage, the individual condition of the patients and the duration of treatment,” Vargas added.

The primary source of vitamin D is exposure to the sun’s ultraviolet (UV) rays. (iStock)

The American Cancer Society (ACS) has previously referenced studies suggesting that vitamin D could lower cancer risk, particularly colorectal cancer.

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“However, large studies have not found that vitamin D supplements lower the risk of colorectal polyps (pre-cancerous growths) or cancer,” the ACS stated on its website.

“The optimal dosage should be tailored to the individual’s health condition and current vitamin D levels.” 

One important limitation of the research is that the studies included in the analysis used different vitamin D dosages and involved patients at various stages of cancer, the authors noted. 

They called for further research to accurately determine the optimal dosage and “therapeutic efficacy.”

Recommendations for Americans

“Based on our research, we recommend that individuals at high risk of colorectal cancer monitor their vitamin D levels and, if necessary, take a daily vitamin D supplement of 1000–4000 IU, especially for those with low vitamin D levels,” lead study author Dr. Monika Fekete, medical doctor at Semmelweis University, told Fox News Digital.

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“The optimal dosage should be tailored to the individual’s health condition and current vitamin D levels.” 

For physicians, the researchers suggest routinely measuring and supplementing vitamin D levels for both prevention and treatment purposes.

“Vitamin D plays a crucial role in the treatment and prevention of colorectal cancer, but further research is needed to determine the optimal dosage and the specific role of genetic factors,” Fekete added.

One important limitation of the research is that the studies included in the analysis used different vitamin D dosages and involved patients at various stages of cancer, the authors noted.  (iStock)

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“The molecular mechanisms of vitamin D — such as the regulation of oncogenes (mutated genes that can lead to cancer) and inhibition of tumor progression — require further scientific investigation.”

As the effect of vitamin D is closely linked to the patient’s condition, the doctor said, treatment recommendations should be personalized.

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The primary source of vitamin D is exposure to the sun’s ultraviolet (UV) rays.

It can also be obtained from dietary sources, according to the ACS, including fatty fish and some mushrooms.

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Some foods, including milk and some orange juices and cereals, are fortified with vitamin D. (iStock)

There are also some vitamin D-fortified foods, including milk, some orange juices and cereals, the above source stated.

People can also take vitamin D supplements to boost their levels.

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“Most Americans do not get enough vitamin D in their diets, and many have low vitamin D levels in their blood,” the ACS said on its website. 

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“While the role of vitamin D in lowering cancer risk is still an active area of research and debate, avoiding low vitamin D levels is recommended.”

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GLP-1 Menus Are Here! What to Order at Every Chain

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GLP-1 Menus Are Here! What to Order at Every Chain


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Men face hidden heart risk years earlier than women, study suggests

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Men face hidden heart risk years earlier than women, study suggests

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Men are at a much higher risk of heart attacks than women earlier in life, a new study reveals.

Researchers at Northwestern University found that men start to develop coronary heart disease years earlier than women, with differences emerging as early as the mid-30s, according to a press release.

The study, published in the Journal of the American Heart Association (JAHA), analyzed data from more than 5,000 adults, aged 18 to 30, from the mid-1980s through 2020, as part of the Coronary Artery Risk Development in Young Adults (CARDIA) analysis.

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Men reached a 5% incidence of cardiovascular disease, including heart attack, stroke and heart failure, at around 50 years old compared to 57 for women.

Coronary heart disease, which is when blood vessels that supply the heart muscle become narrowed or blocked, was the main driver of the difference, as men reached a 2% incidence more than a decade before women. Stroke and heart failure emerged later in life.

Heart disease risk among men rises faster at around 35 years of age, research finds. (iStock)

Men’s risk began rising faster at around age 35 and remained high throughout midlife, according to the research. Everyone in the study was under 65 years old at the last follow-up. 

Current guidelines generally recommend cardiovascular risk assessment beginning around age 40, which some experts say may miss an important window for early prevention.

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COMMON DENTAL HEALTH ISSUE MAY HINT AT MORE DANGEROUS MEDICAL CONDITION

Heart disease develops over decades, with early markers detectable in young adulthood, according to senior study author Alexa Freedman, assistant professor of preventive medicine at Northwestern University Feinberg School of Medicine.

Lifestyle factors are most likely the main driver of cardiovascular events in men, a cardiologist suggests. (iStock)

“Our findings highlight the importance of promoting heart health screening and prevention in young adulthood, especially for young men,” Freedman told Fox News Digital.

The researchers emphasized the importance of looking beyond standard measures of heart risk, like cholesterol or blood pressure, and considering a “broader range of biological and social factors.”

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Dr. Andrew Freeman, cardiologist and director of clinical cardiology at National Jewish Health in Denver, was not involved in the study but commented on the findings.

“We have always known that men tend to manifest and typically die earlier from things like heart attacks and strokes compared to women,” he told Fox News Digital.

The lead researcher recommends more frequent or early CT angiograms to help prevent cardiac events. (iStock)

Although the study did not identify why more men are predisposed to heart issues than women, Freeman said factors like hormonal differences, diet and physical activity could come into play. 

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“The standard American lifestyle makes us all sick, and then men seem to be more prone to developing this disease earlier,” the cardiologist told Fox News Digital. 

“We are more exposed to toxins than ever before in virtually every part of our food supply,” he added. “We already know well that air pollution, light pollution and sound pollution are all associated with earlier heart disease.”

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Americans are also more sedentary, get less sleep, are more stressed and are less socially connected, all of which can increase cardiovascular diseases, Freeman added.

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“I think this study is really underscoring that it’s time for some big changes,” he said.

Regular daily exercise is one way to set up your heart for a long life, experts agree. (iStock)

The doctor shared the following five “healthspan” tips to help prevent heart health issues.

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  1. Limit toxin exposure in the form of alcohol, tobacco, marijuana, nicotine and air pollution
  2. Eat a predominately low-fat, whole-food, plant-based diet
  3. Exercise regularly, ideally 20 to 30 minutes every day at a level of breathlessness (with sign-off from a doctor)
  4. Partake in stress-relieving activities and mindfulness exercises
  5. Get adequate, uninterrupted sleep
  6. Cultivate a strong support network of friends and family

“We need to do everything we can to clean up our lifestyles and reduce our disease burden.”

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Freeman also recommends addressing any comorbidities, like high blood pressure, high cholesterol and obesity.

Those at a higher risk of cardiovascular events may want to consider earlier screening, although Freeman suggested that early prevention efforts should apply to everyone.

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“Coronary disease is manifesting earlier than ever here in the U.S., and we need to do everything we can to clean up our lifestyles and reduce our disease burden,” he said. “If you’re a man, you’ve got to be extra aggressive earlier in life.”

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Simple weight-loss quiz may pinpoint why some diets fail — and how to boost success

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Simple weight-loss quiz may pinpoint why some diets fail — and how to boost success

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Weight loss can be highly dependent on each individual’s habits and relationship with food.

With this in mind, new research from City St. George’s, University of London, found that categorizing people into “eating profiles” can help people achieve lasting results.

The study was based on an online quiz developed by the university, which led participants through 17 questions asking about their behavioral habits regarding emotional eating, dieting and exercise.

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Quiz-takers were grouped into four profiles, or phenotypes, based on their responses: Purple Lavender, Red Chili, Yellow Saffron and Green Sage.

The quiz then offered tailored advice for building a healthier long-term lifestyle, including how to stick to personal goals, improve dietary choices and incorporate more movement.

The university questionnaire takes behavioral habits into consideration before assigning an eating profile. (iStock)

The U.K. study participants were enrolled in a 12-week digital weight-loss program, in addition to seven weeks of tailored advice.

Those who took the quiz and identified with a profile showed “significant” engagement in the 12-week program compared to those who did not. They were also more likely to stick to it, according to the university.

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Quiz-takers also recorded more meals, communicated with health coaches more frequently and lost more weight on average.

“Phenotype-tailored weekly advice was associated with substantially higher engagement in a real-world digital program, although short-term weight differences were not statistically significant,” the authors concluded in the study, which was published in JMIR Formative Research.

Quiz-takers were grouped into four profiles, or phenotypes, based on their responses: Purple Lavender, Red Chili, Yellow Saffron and Green Sage. (iStock)

Although the study was not randomized, followed participants for only a short time and relied on self-reported weight, the results suggest that adjusting digital weight-loss programs based on how people typically eat and behave could help more users stick with them, the researchers said.

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Larger, randomized trials with longer follow-ups are “warranted to determine whether increased engagement translates into clinically meaningful weight loss,” they added.

Fox News Digital reached out to the study authors for comment.

Breaking down the 4 eating profiles

According to the researchers, “Red Chili” is characterized by “high maladaptive and hedonic eating, low self-regulation and high psychological avoidance.”

This means Red Chili members may feel their eating is out of control, use food to cope with negative emotions, feel guilty about their eating habits and tend to ignore problems. This group also tends to follow restrictive diets, but then overeats when it doesn’t pan out.

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Those assigned to an eating profile were more engaged in losing weight. (iStock)

“Yellow Saffron” is based on “high hedonic eating and reward reactivity and low maladaptive eating.”

These individuals may find it difficult to resist overeating, choose foods based on taste rather than health benefits, and frequently crave foods high in calories, fat and sugar.

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“Purple Lavender” represented “low self-regulation and high psychological avoidance, as well as low maladaptive and hedonic eating.”

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This group tends to set goals and pursue them temporarily, but may give up upon confronting an obstacle. Purple Lavenders may lose enthusiasm after starting to make changes and find it difficult to continue, as well as ignore problems and challenges.

“Green Sage” is characterized in the quiz as “low maladaptive and hedonic eating, high self-regulation and low psychological avoidance.”

“There is no general way of eating that suits each person, because behavior and personality play such a role.”

These individuals often need clear guidance in making positive lifestyle changes, yet put off working toward goals when they lack motivation.

People in Green Sage may tend to not do the recommended amount of physical activity for their health or eat the recommended amount of vegetables for their diet, even if they often cook at home.

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Experts weigh in

Los Angeles-based registered dietitian-nutritionist Ilana Muhlstein praised the “really intuitive” quiz.

“It really hits on the emotional and behavioral side of weight loss that people struggle with the most,” the California-based expert told Fox News Digital.

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“It did an amazing job once it identified your eating type, giving you mindset shifts and descriptors on what to work on,” she went on. “It’s no surprise to me that it made a significant difference in the motivation and adherence to the weight-loss plan early on.”

Effective weight loss begins with identifying habits and behaviors, experts say. (iStock)

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As the results found no significant difference at the seven-week mark, Muhlstein suggested that this means the researchers “have to work on better follow-up measures” to help people stay more consistent.

Certified holistic nutritionist Robin DeCicco added that it “makes sense” to acknowledge habits and behaviors around food to promote weight loss and health goals.

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“Health is an individualized topic. There is no general way of eating that suits each person, because behavior and personality play such a role,” the New York expert told Fox News Digital. 

“Following a generic diet of what to eat and what to avoid doesn’t result in any sort of meaningful change unless personality types, behaviors and habits are addressed.”

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