Health
Chicago man receives kidney transplant while fully awake, goes home very next day
Kidney transplants are not uncommon — the kidney is actually the most frequently transplanted organ in the U.S. — but a Chicago man recently received his in a highly unusual way.
John Nicholas, 28, was awake during the entire procedure, which was performed on May 24 at Northwestern Medicine Hospital. He was discharged the very next day.
Doctors administered a spinal anesthesia shot — similar to what is used for a Cesarean section — instead of general anesthesia, according to a press release from the hospital.
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“This is the first case at Northwestern Medicine where a patient was awake during an entire kidney transplant procedure and went home the next day, basically making this an outpatient procedure,” said Satish Nadig, M.D., PhD, transplant surgeon and director of the Northwestern Medicine Comprehensive Transplant Center, in the release.
“Inside the operating room, it was an incredible experience being able to show a patient what their new kidney looked like before placing it inside the body,” he added.
John Nicholas, the patient, is pictured with his surgeons in the operating room after completion of the kidney transplant. (Northwestern Medicine)
“It was incredibly simple and uneventful.”
This type of “awake transplant” could reduce surgical risks and shorten the length of the patient’s hospitalization, doctors say.
“It was an incredible experience, being able to show a patient what their new kidney looked like before placing it inside the body.”
It could also increase access to care for patients who are considered high-risk or have phobias surrounding general anesthesia.
Ideal candidate
Nicholas’ surgery took about two hours, according to the hospital.
He was considered an ideal patient for awake surgery due to his young age, his otherwise good health and his “eagerness to participate,” per the release.
John Nicholas is pictured awake during his kidney transplant in late May. (Northwestern Medicine)
“It was a pretty cool experience to know what was happening in real time and be aware of the magnitude of what they were doing,” said Nicholas in a statement to Northwestern.
“At one point during surgery, I recall asking, ‘Should I be expecting the spinal anesthesia to kick in?’ They had already been doing a lot of work and I had been completely oblivious to that fact. Truly, no sensation whatsoever.”
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Although Nicholas did receive sedation for comfort, he said he was still aware of what was going on.
“Especially when they called out my name and told me about certain milestones they had reached,” he noted.
Nicholas, center, is pictured after surgery with Dr. Vicente Garcia Tomas, his anesthesiologist, at left, and Dr. Nadig, transplant surgeon, at right. (Northwestern Medicine)
Nicholas walked out of the hospital on May 25, the day after surgery.
With typical kidney transplants, the recipient remains in the hospital for two to three days.
Saved by a friend
Nicholas’ kidney issues began at age 16 when he was diagnosed with Crohn’s disease, the release stated.
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After a few years of managing the condition with medication, his kidney function worsened and he required a transplant.
Nicholas’ mother originally planned to donate her kidney, but a breast cancer diagnosis prevented her from doing so, the hospital relayed.
Nicholas, at left, is pictured with his donor and best friend, Pat Wise, after surgery. (Northwestern Medicine)
It was Nicholas’ best friend from elementary school, 29-year-old Pat Wise in Alexandria, Virginia, who ultimately donated the life-saving kidney.
‘Another tool in our toolbelt’
Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, was not involved in the surgery but shared his input.
“My opinion is that in most cases, spinal anesthesia presents a reasonable alternative for those at high risk of general anesthesia complications,” Siegel told Fox News Digital.
Nicholas is pictured awake with his care team during his kidney transplant surgery. (Northwestern Medicine)
“Having said that, general anesthesia would be preferred whenever possible for major surgery like this,” said Dr. Siegel, “because control of the airway and breathing is essential, and is much easier if the patient is asleep and on the ventilator.”
The doctors at Northwestern credit the patient for helping to advance the field of transplant medicine.
Nicholas, left, and donor Wise are pictured at a press conference after the surgery. (Northwestern Medicine)
“When John agreed to be the first known patient at Northwestern Medicine to undergo an awake kidney transplant and be discharged home the next day, he knew the benefits outweighed the risks, and … he’s now helping to move the field of transplantation forward,” said Vinayak Rohan, M.D., transplant surgeon at Northwestern Memorial Hospital, in the release.
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“He is an extremely compliant patient who was in tune with his body and willing to push the envelope,” stressing that the patient had faith in the doctors and they, in turn, had faith in him.
Nicholas, center, is pictured with his entire care team. “He’s now helping to move the field of transplantation forward,” a surgeon said about the patient. (Northwestern Medicine)
The hospital now plans to establish the AWAKE Program (Accelerated Surgery Without General Anesthesia in Kidney Transplantation) for patients who want or need to pursue surgery without general anesthesia.
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“It really opens up a whole new door and is another tool in our toolbelt for the field of transplantation,” Nadig added.
Fox News Digital reached out to Northwestern Medical for additional input.
Health
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Health
Dr Oz warns Medicare scammers are stealing billions — and your personal information could be next
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Washington, D.C. – Medicare fraud is a multibillion-dollar problem that government officials say threatens both taxpayer dollars and Americans’ personal identities.
In a July 6 interview with Fox News Digital at the Great American State Fair in Washington, D.C., Dr. Mehmet Oz warned that every dollar stolen through Medicare fraud is a dollar taxpayers lose – a problem that has worsened since the COVID pandemic.
“If I had to just pick one thing to focus on to make healthcare more affordable in America, I’d go to health fraud and all the waste and abuse that accompanies it,” said Oz, who is the administrator of the Centers for Medicare & Medicaid Services. “And just to put this in perspective, we think it’s about $100 billion a year.”
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Medicare fraud can include billing for services that were never provided, overcharging for medical equipment, using stolen patient or doctor information, or performing unnecessary procedures, according to the U.S. Government Accountability Office.
CMS administrator Dr. Mehmet Oz is pictured on stage at the Great American State Fair in Washington, D.C., on July 6, 2026. (Angelica Stabile/Fox News Digital)
As the Trump administration ramped up efforts to combat fraud, CMS reported $41.9 billion in Medicare program integrity savings in 2025, up 59% from $26.3 billion in 2024.
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Medicare fraud not only harms the federal budget and steals from taxpayers, but exposes seniors to identity theft, unnecessary care, higher premiums and reduced access, Oz cautioned.
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Removing corruption from the healthcare system will have the greatest impact among seniors, since “so much of the fraud is perpetrated against them,” the administrator said.
“I’m talking about people tricking seniors to give up their Medicare beneficiary numbers, which is like a credit card basically,” he said. “These scammers can take those numbers and use them for all kinds of illegitimate purposes.”
“If I had to just pick one thing to focus on to make healthcare more affordable in America, I’d go to health fraud and all the waste and abuse that accompanies it,” said Oz. (Fox News Digital)
“People are stealing from you by pretending to send you drugs you don’t want, wheelchairs you don’t need, [and] services you never asked for or don’t benefit from,” Oz added.
To prevent this, he shared his top advice for seniors: Do not give your Medicare beneficiary number to anybody, do not answer questions on a phone call from an unknown person and do not give away personal information.
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“These scammers are calling seniors, tricking them, and once they have key information, they can steal it,” he said. “And I won’t know it and you won’t know it.”
“We want to protect people who need these programs the most,” Oz went on. “You do that by making sure scoundrels don’t corrupt the systems and steal money out of the till that is designed to help folks in dire straits when they’re vulnerable and in need of services.”
Seniors should never share their Medicare information with unknown people, the administrator advised. (iStock)
Removing fraud could “double the life expectancy of the trust fund that makes all this possible,” Oz predicted.
“If you’re worried about Medicare being there when you’re ready to retire in a couple decades, depending on how old you are, and you’re concerned that it might not last because of all the fraud that’s hitting it … you’ve got a good [reason to] worry,” he said.
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“If we take the fraud out, we could double the life expectancy, which means you, your kids, your kids’ kids … they could all benefit from this beautiful safety net program.”
Health
Common gym supplement could help fight depression, new research suggests
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Creatine, the common muscle-building supplement, may help improve depression symptoms, new research suggests.
A systematic review, published in Genomic Press’ Brain Medicine, found that creatine monohydrate may be beneficial as an add-on treatment for major depressive disorder, although the evidence remains preliminary.
The Canada-based researchers analyzed data from five randomized controlled trials, evaluating the impact of creatine monohydrate intake on mental health.
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Four of the trials studied major depressive disorder, and another looked at bipolar disorder with a current depressive episode.
In one trial of women with depression who took 5 grams of creatine per day, plus the antidepressant escitalopram, there was greater improvement after eight weeks. Another study revealed benefit when creatine was added to cognitive behavioral therapy.
One study saw benefit when creatine was added to cognitive behavioral therapy. (iStock)
Other studies involving teen girls found no benefit from a variety of creatine dosages after eight weeks. The bipolar depression study also found no significant improvements when 6 grams of creatine was added to medication after six weeks.
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In a press release, the researchers said previous studies have found that people with mood disorders process creatine differently in the brain. Because creatine helps produce energy, some scientists believe disruptions in this process may contribute to depression.
Although creatine has also been associated with boosting dopamine and serotonin, which most antidepressants target, the authors stressed that the link between brain creatine and mood “remains correlational,” as depression has “many moving parts.”
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Lead study author Bassam Jeryous Fares, a student in the Faculty of Medicine at the University of Ottawa, commented in a statement that the signal is “interesting, but not a verdict.”
“Two trials pointed one way and three pointed another,” he said. “That is not the kind of evidence on which you change clinical practice. It is the kind that tells you the question is worth further exploration.”
Although creatine has also been associated with boosting dopamine and serotonin, which most antidepressants target, the authors stressed that the link between brain creatine and mood “remains correlational.” (iStock)
Nicholas Fabiano, corresponding author and a psychiatry resident at the University of Ottawa, added in the same press release that creatine “appears to be a safe intervention,” noting that side effects were limited to mild stomach pain.
“We cannot yet reliably say that creatine helps with depressive symptoms or if the findings are generalizable to everyone,” he added as a caveat.
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Dr. Thea Gallagher, psychologist and director of wellness programs at NYU Langone, said that although creatine is best known for supporting muscle performance, it also helps the brain produce and use energy.
“Researchers believe that some people with depression may have alterations in brain energy metabolism, and creatine could help support these energy-producing pathways,” Gallagher, who was not involved in the study, told Fox News Digital. “There is also emerging evidence that it may influence neurotransmitters and reduce oxidative stress and inflammation, although these mechanisms are still being investigated.”
Creatine should be considered a “promising addition” to depression treatments, a doctor said. (iStock)
The research suggests that creatine may be most helpful when combined with established depression treatments rather than as a replacement, Gallagher emphasized.
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“This research is encouraging because it adds to a growing body of evidence suggesting that supporting brain energy metabolism may be another pathway for improving depression symptoms,” she said.
“It’s exciting whenever we identify another potential tool that could complement existing treatments, particularly one that is relatively inexpensive and widely available.”
Limitations and caveats
The new study is a review of prior research rather than a new clinical trial, which can pose a limitation, the researchers acknowledged, adding that “larger, well-controlled trials are still needed.”
Gallagher noted that creatine should be considered as a potentially promising addition to treatment, rather than a substitute for psychotherapy, antidepressant medication, regular exercise or healthy sleep habits.
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“While creatine has a strong safety profile for most healthy adults, it’s still important to talk with your healthcare provider before starting any supplement — particularly if you have kidney disease, are pregnant or have other medical conditions,” she advised.
For those experiencing signs of depression, Gallagher recommends seeking evidence-based mental healthcare.
“While creatine has a strong safety profile for most healthy adults, it’s still important to talk with your healthcare provider before starting any supplement – particularly if you have kidney disease, are pregnant or have other medical conditions,” a doctor advised. (iStock)
The doctor noted that depression is a “highly heterogeneous condition, so we still don’t know which patients are most likely to benefit or what the optimal treatment approach looks like.”
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Gallagher also cautioned that supplements have been known to generate “early enthusiasm” before larger studies have revealed “more modest effects.”
“Right now, I’d describe creatine as promising but not definitive,” she concluded. “It’s an area that deserves continued research, but it’s not something people should view as a standalone treatment for depression.”
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