Health
Breast cancer patient says new type of chemo saved her life: ‘I am thriving’
Just as no two cancers are the same, treatment isn’t one-size-fits-all — and for one Arizona mother and teacher, personalized chemotherapy became the path to survival.
Tammy Morrow, 55, had been healthy for decades when, after seeing a doctor for what she thought was a stomach bug in December 2023, she was blindsided by a diagnosis of stage 4 metastatic breast cancer.
The cancer had spread to her bones, lymph nodes, liver and other areas, she told Fox News Digital. It became evident fairly quickly that her disease was beyond the scope of traditional treatments.
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“I received one round of traditional chemo in the hospital,” said Morrow, who lives in Phoenix, Arizona. “After just the one treatment, all of my hair fell out within just eight days.”
Tammy Morrow, center, is pictured with her two sons, Gabriel and Izaak Morrow. “I am persuaded that I would not be alive today if I had not received care at Envita,” she told Fox News Digital. (Derek Morrow)
“The rapid hair loss demonstrates the systemic nature and toxicity of traditional chemo,” she added.
Morrow’s oncologist told her that she likely only had months to live, but she was determined to find another alternative.
Through her research, she found Envita Medical Center in Scottsdale, which offers a novel cancer treatment called Genetically Targeted Fractionated Chemotherapy (GTFC).
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“When I arrived at Envita, I was not taking in food orally, and for almost three months, I had to receive all of my nutrition from a catheter delivered directly into my veins,” Morrow said.
She began receiving GTFC treatments, which she credits as “essential to survival.”
“In just 21 weeks, my diagnosis changed from terminal to normal.”
“I am persuaded that I would not be alive today if I had not received care at Envita,” Morrow told Fox News Digital.
“Now, I am thriving.”
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Morrow’s last several blood tests have shown no evidence of disease, and her most recent PET scan in May confirmed that she is cancer-free.
“In just 21 weeks, my diagnosis changed from terminal to normal,” she said.
Making it personal
Genetically targeted fractionated chemotherapy (GTFC) is a targeted approach to cancer treatment that personalizes chemotherapy based on a patient’s genetic makeup and specific tumor biology, according to Dr. John Oertle, chief medical director at Envita Medical Centers.
Tammy Morrow is pictured with her husband, Derek Morrow, before her diagnosis. (Tammy Morrow)
“This method also enhances the tumor’s ability to absorb the chemotherapy, allowing us to use reduced dosages while maintaining effectiveness,” Oertle, who specializes in “individualized, outcome-based care models for chronic disease and integrative oncology,” told Fox News Digital.
GTFC is designed to deliver medicine with more precision while having fewer side effects, he noted.
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“Conventional chemotherapy targets all rapidly dividing cells, both cancerous and healthy, using high doses, which often leads to widespread side effects,” Oertle said.
“Additionally, we have found that 90% of patients on conventional chemotherapy are dealing with cancer that has already become resistant to it.”
Morrow had been healthy for decades when, after seeing a doctor for what she thought was a stomach bug in December 2023, she was blindsided by a diagnosis of stage 4 metastatic breast cancer. (Tammy Morrow)
GTFC is designed to specifically target cancer cells with genetic mutations, he said, so that more chemo gets into the tumor.
“While only 5% to 7% of conventional chemotherapy administered through an IV typically reaches the tumor, GTFC significantly improves this uptake,” Oertle said.
“As a result, we can reduce the overall dosage and administer treatment more frequently.”
“Not only are these specific treatments resulting in better outcomes, they are less harmful as well.”
Fox News medical contributor Dr. Nicole Saphier, who is not associated with Envita, referred to GTFC as “the future of cancer treatment.”
“Historically, we depended on traditional chemotherapy to kill cancer cells,” she told Fox News Digital.
“Unfortunately, traditional chemotherapy isn’t very specific, so while it killed cancer cells, it also killed healthy cells.”
In the midst of cancer treatments, as she began losing her hair, Morrow had a friend give her a haircut. (Tammy Morrow)
Because of this limitation, traditional chemo can have “severe” short-term and long-term side effects, Saphier confirmed.
“GTFC is a targeted therapy, which is a type of cancer treatment that’s designed to attack cancer cells while leaving healthy cells alone,” she went on.
“Not only are these specific treatments resulting in better outcomes, they are less harmful as well.”
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While there are some possible side effects with GTFC, they are “significantly fewer” than with traditional chemo, Oertle said.
“Many patients are even able to maintain their hair,” he added.
Morrow, seen here with a few of her fitness friends at the gym, was an avid health and wellness enthusiast before getting diagnosed. (Tammy Morrow)
In Morrow’s case, she said her side effects were “minimal,” even after receiving GTFC chemo treatments once or twice every week for 21 weeks.
Her main side effects were weakness and digestive issues for a day or two after the treatment.
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“I was even able to work full-time during my treatment,” she said. “On a couple of occasions, I virtually attended work meetings while receiving the chemo treatments.”
Who can get GTFC?
In addition to breast cancer, GTFC can be an option for any type of cancer that needs systemic therapy, according to Oertle.
“For early-stage cancers, we utilize advanced blood tests to ensure that the disease has not spread,” he said.
“I pray that one day, I will have the money to help others receive care at Envita,” Morrow said. (Tammy Morrow)
“If the cancer remains localized, we offer other precision-based, less invasive treatments that may eliminate the need for GTFC. However, for cancers that have spread beyond the initial tumor, GTFC may be an effective treatment option.”
“Most people simply cannot afford to pay for this type of medical care.”
There are some barriers to receiving this type of chemo, however.
“It is very difficult to receive this care because no insurance company in America will cover the advanced and targeted integrated care Envita offers,” Morrow told Fox News Digital.
“Even though the chemotherapy drugs I received at Envita are a part of the normal medical protocol, because the method of delivering these chemotherapy drugs is not normal, my insurance company refused to cover any of it.”
While there are some possible side effects with GTFC, they are “significantly fewer” than with traditional chemo, an expert said. (iStock)
Morrow paid nearly $250,000 out of pocket for her chemo treatments.
“Most people simply cannot afford to pay for this type of medical care — and I could not have afforded it, either,” she said.
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To cover the cost, Morrow’s two sons started a GoFundMe and raised almost $120,000, and Morrow and her husband took out a second mortgage to cover the rest.
“I would encourage people to not let the cost prevent them from seeking out this innovative and life-saving approach to cancer care,” Morrow urged.
In addition to breast cancer, GTFC can be an option for any type of cancer that needs systemic therapy. (iStock)
“I pray that one day, I will have the money to help others receive care at Envita. In the meantime, my husband and I have two guest bedrooms waiting to be filled by out-of-town patients.”
Envita includes the below disclaimer on its website.
For more Health articles, visit www.foxnews.com/health
“Disclaimer: Individual results will vary. Envita makes no guarantees for outcomes. Each patient’s case is unique. Please consult your doctor before making any changes to your medical treatment. Not every patient is a candidate for care or achieves these results. Treatments used in this case may not all be FDA-approved for the treatment of this condition.”
Fox News Digital reached out to the FDA requesting comment.
Health
New cancer vaccine delivers stunning result against one of the deadliest skin cancers
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A new injectable therapy is showing positive results in reducing melanoma throughout a five-year period.
The personalized mRNA cancer therapy, called intismeran autogene, combined with the cancer immunotherapy drug KEYTRUDA (pembrolizumab), is a collaboration between Merck and Moderna.
The results from the phase 2b KEYNOTE-942 study were presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on May 27.
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After about a five-year follow-up, the combo drug was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone.
The researchers analyzed data from 157 patients with high-risk stage 3 and 4 melanoma whose cancer had been removed via surgery. The participants were split into two groups — one received the combo therapy and the other only received pembrolizumab, according to a press release.
The therapy was found to reduce the risk of melanoma recurrence or death by 49% compared to pembrolizumab alone after a five-year follow-up. (iStock)
The findings revealed that the combination group saw benefits that were “sustained and durable over time.”
Intismeran autogene is designed using mutations identified in a patient’s own tumor, with the intention of teaching the immune system what the cancer looks like so that it can recognize and attack it.
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According to the researchers, intismeran is “well-tolerated” with a “manageable” safety profile.
The most commonly cited side effects of the personalized mRNA vaccine plus KEYTRUDA were fatigue, injection-site pain, chills, fever and headache. The researchers reported no new long-term safety concerns and no severe vaccine-related adverse events.
The combination therapy is currently being evaluated in a phase 3 study — the final confirmation stage.
Patients with late-stage melanoma have a “significant risk” of cancer recurrence, according to an expert. (iStock)
In a Merck press release from January, Kyle Holen, MD, Moderna’s senior vice president and head of development, oncology and therapeutics, noted that this data highlights the “potential of a prolonged benefit … in patients with resected high-risk melanoma.”
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“We continue to invest in our platform in oncology because of encouraging outcomes like these, which illustrate mRNA’s potential in cancer care,” he said.
Dr. Marjorie Green, senior vice president and head of oncology, global clinical development at Merck Research Laboratories, also commented that for many patients with stage 3 or 4 melanoma, there is a “significant risk of recurrence following surgery.”
Researchers confirmed that the combination therapy is currently being evaluated in a phase 3 study. (iStock)
“As such, demonstrating the longer-term potential of intismeran autogene and KEYTRUDA to reduce the risk of recurrence for certain patients with melanoma is a meaningful milestone,” she said.
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The company cited encouraging five-year follow-up data and pointed to upcoming late-stage INTerpath trial results with Moderna in several hard-to-treat cancers.
Health
New ways to prevent flu revealed in ‘accidental’ lab breakthrough, study finds
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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.
By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.
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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.
“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)
While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.
Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.
“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”
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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.
The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.
Clinical treatments remain identical for both primary strains of the flu virus. (iStock)
During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.
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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.
Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.
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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.
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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”
This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)
“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”
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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.
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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.
Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.
Health
One extra serving of processed meat a day linked to higher cancer risk
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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.
While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.
To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years.
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The study group included 131,426 men and 318,686 women, according to the study’s press release.
During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.
For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)
Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.
The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.
BACTERIA IN YOUR MOUTH MAY TRAVEL TO THE GUT AND TRIGGER STOMACH CANCER, RESEARCH FINDS
After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.
A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.
An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)
An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.
The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.
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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.
The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.
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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.
Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)
Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.
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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.
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The findings were published in the International Journal of Cancer.
Fox News Digital reached out to the researchers requesting comment.
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