Health
An Effective Treatment for Opioid Addiction Exists. Why Isn’t It Used More?
Then, in November, with the election of Donald Trump and the Republicans’ return to power in Congress, the question of how best to respond to opioid-use disorder was confronted with new uncertainty. For the past decade, the push to expand access to treatment for opioid addiction has enjoyed bipartisan support. But during his campaign, Trump outlined a draconian vision to address the opioid problem, threatening drug dealers and smugglers with the death penalty and promising to “seal” the border. On Feb. 1, he signed an executive order to levy tariffs against China, Mexico and Canada, in part to pressure these countries to halt the flow of fentanyl into the United States. (Soon after, he gave 30-day reprieves to Canada and Mexico.)
Keith Humphreys, a professor of psychiatry and behavioral sciences at Stanford who studies the opioid crisis, says the idea that beefed-up border control could halt or greatly curtail the flow of fentanyl into the country is simply misguided. Fentanyl is so concentrated that the amount needed to supply the entire country’s demand for a year is at most 10 metric tons, he estimates. Law enforcement has to find those 10 tons — the weight of few cars — among the more than seven million trucks carrying goods that cross the border annually. To meaningfully impede the flow of fentanyl, he thinks, you would have to completely close the border, at which point the country would inflict massive economic harm on itself. And even with the border shut, drones, planes and tunnels can easily continue supplying the market. A birthday-card-size letter mailed from abroad could carry a week’s supply of the opioid for someone. “You can’t really keep fentanyl out of such a big country,” he says.
Trump’s expressed desire to slash government spending also worries proponents of medication-for-addiction treatment. Some Republicans are actively seeking ways to cut Medicaid, along with other federal programs. Trump may also try to undo or simply undermine the Affordable Care Act, a favorite target. Either development could be disastrous for the distribution of medication to treat opioid addiction, reversing the gains, however tenuous, made under the Biden administration. Medicaid covers an estimated 40 percent of non-elderly adults with opioid-use disorder in the United States, some two-thirds of whom receive treatment for their addiction through the program.
It’s also possible, however, that Trump will expand the public-health approach he embraced during his first term, which was furthered by the Biden administration, and continue to encourage efforts to roll out M.A.T. Trump signed a law during his first term that removed some requirements for doctors who wanted to prescribe buprenorphine, notes Kassandra Frederique, the executive director of Drug Policy Alliance, a nonprofit that advocates for less-punitive drug policy. And uniquely among Republican presidents, Trump supported the use of some harm-reduction practices like making clean syringes available, according to his first-term surgeon general. Frederique told me she hopes that the current administration will continue to build on the work Trump and others have done to expand access to treatment.
What’s important to remember is just how much evidence exists indicating that buprenorphine can help people with opioid addiction. Sarah Wakeman often points this out as she pushes back against what she sees as a pervasive sense of pessimism around the opioid crisis. The problem is that this medicine isn’t getting to the people who need it quickly enough. “Most people think this is a terribly recalcitrant, untreatable, insurmountable problem,” she says. “That couldn’t be further from the truth.”
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Feeling lonely may take a toll on older adults’ memory — but it may not speed up cognitive decline, according to a new study.
Researchers from Colombia, Spain and Sweden analyzed data from more than 10,000 adults ages 65 to 94 across 12 European countries and found those who reported higher levels of loneliness did worse on memory tests at the start of the study, according to research published this month in the journal Aging & Mental Health.
Over a seven-year period, however, memory decline occurred at a similar rate regardless of how lonely participants felt.
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“The finding that loneliness significantly impacted memory, but not the speed of decline in memory over time was a surprising outcome,” lead author Dr. Luis Carlos Venegas-Sanabria of the School of Medicine and Health Sciences at the Universidad del Rosario said in a statement.
Loneliness may be linked to memory performance in older adults, a new study suggests. (iStock)
“It suggests that loneliness may play a more prominent role in the initial state of memory than in its progressive decline,” Venegas-Sanabria said, adding that the findings highlight the importance of addressing loneliness as a factor in cognitive performance.
The findings add to debate about whether loneliness contributes to dementia risk. While loneliness and social isolation are often considered risk factors for cognitive decline, research results have been mixed.
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The study looked at data from the long-running Survey of Health, Ageing and Retirement in Europe (SHARE), which tracked 10,217 older adults between 2012 and 2019. Participants were asked to recall words immediately and after a delay to measure memory performance.
Social isolation and loneliness could play a surprising role in cognitive health among seniors. (iStock)
Loneliness was assessed using three questions about how often participants felt isolated, left out or lacking companionship.
About 8% of participants reported high levels of loneliness at the outset. That group tended to be older, more likely to be female and more likely to have conditions such as depression.
DEMENTIA RISK SIGNALS COULD LIE IN SIMPLE BLOOD PRESSURE READINGS, SAY RESEARCHERS
Researchers found that those with higher loneliness had lower scores on both immediate and delayed memory tests at baseline. Still, all groups — regardless of loneliness level — experienced similar declines in memory over time.
The results suggest loneliness may not directly accelerate the progression of memory loss, though it remains linked to poorer cognitive performance overall.
Researchers look at a brain scan at the National Institutes of Health in Bethesda, Maryland. (Saul Loeb/AFP/Getty Images)
Experts warn, however, that the findings should not be interpreted to mean loneliness is harmless.
“The finding that lonely older adults start with worse memory but don’t decline faster is actually the most interesting part of the paper, and I think it’s easy to misread,” said Jordan Weiss, Ph.D., a scientific advisor and aging expert at Assisted Living Magazine and a professor at NYU Grossman School of Medicine.
“It likely means loneliness does its damage earlier in life, well before people show up in a study like this at 65-plus,” Weiss told Fox News Digital.
By older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold, an aging expert says. (iStock)
He suggested that by older age, long-term social patterns may already be established, making it harder to detect when the effects of loneliness first took hold.
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“By the time you’re measuring someone in their late 60s, decades of social connection patterns are already baked in,” he said.
Weiss, who was not involved in the research, added that loneliness may coincide with other health conditions, and noted that participants who felt more isolated also had higher rates of depression, high-blood pressure and diabetes. The link, he said, may reflect a cluster of health risks rather than a direct cause.
“While they can go hand-in-hand, it’s not clear that loneliness contributes to dementia,” a psychotherapist says. (iStock)
Amy Morin, a Florida-based psychotherapist and author, said the findings reflect a broader pattern in research on loneliness and brain health, and that the relationship may be more complex than it appears.
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“The evidence shows there’s a link between loneliness and cognitive decline but there’s no direct evidence of a cause and effect relationship,” she said. “So while they can go hand-in-hand, it’s not clear that loneliness contributes to dementia.”
Morin added that loneliness, which can fluctuate, may not be the root of the problem, but rather a symptom of other underlying mental or physical health issues.
Researchers suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging. (iStock)
She said staying socially and mentally engaged is crucial for overall brain health.
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“It’s important to be proactive about social activities,” Morin said. “Joining a book club, having coffee with a friend, or attending faith-based services can be a powerful way to maintain connections in older age.”
The researchers also suggested screening for loneliness be incorporated into routine cognitive assessments as one way to support healthy aging.
Fox News Digital reached out to the researchers for comment.
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Research continues to uncover new details on how fasting may help extend life.
A new study published in the journal Nature Communications investigated how intermittent fasting can boost longevity in small worms often used in aging research.
Researchers from the University of Texas Southwestern Medical Center in Dallas compared worms that were fed normally to those that underwent a 24-hour fast in early adulthood and were then fed again, according to a press release.
POPULAR INTERMITTENT FASTING DIETS MAY NOT DELIVER THE HEALTH BENEFITS MANY EXPECT
The scientists measured a variety of factors, including stored fat, gene activity related to fat metabolism and lifespan.
The results showed that the life-boosting benefit did not depend on the fasting itself but on the body’s behavior after eating again.
Experts say sustainability is key when choosing a long-term weight-loss strategy. (iStock)
Study lead Peter Douglas, associate professor of molecular biology and a member of the Hamon Center for Regenerative Science and Medicine at UT Southwestern, suggested that these discoveries “shift the focus toward a neglected side of the metabolic coin – the re-feeding phase.”
“Our data suggest that the health-promoting effects of intermittent fasting are not merely a product of the fast itself, but are dependent on how the metabolic machinery recalibrates during the subsequent transition back to a fed state,” he said.
PEOPLE LOST WEIGHT WHILE EATING SIGNIFICANTLY MORE FOOD — HERE’S THE SECRET
“Our findings bridge a gap between lipid metabolism and aging research,” he added. “By targeting aging, the single greatest risk factor for human disease, we move beyond treating isolated conditions toward a preventive model of medicine that enhances quality of life for all individuals.”
Lauri Wright, director of nutrition programs at the University of South Florida’s College of Public Health, called this a “high-quality” study that adds an “important nuance to how we think about fasting and longevity.”
Intermittent fasting typically involves limiting meals to an eight-hour daily window or fasting every other day. (iStock)
The benefits of the refeeding phase after fasting were “especially interesting,” Wright, who was not involved in the study, told Fox News Digital.
“The researchers showed that longevity was linked to the body’s ability to turn off fat breakdown after fasting, allowing cells to restore energy balance,” she reiterated.
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“From a scientific standpoint, that’s a meaningful shift because it suggests fasting is not just about burning fat, but about metabolic flexibility.”
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Fasting may support longevity through triggering metabolic switching, enhancing cellular repair and stress resistance and improving markers like insulin sensitivity, research shows.
Limitations and cautions
Although this study provides “important insight” on the power of refeeding, Wright noted that the findings should be approached with caution, as the study was done on worms and cannot always be translated to humans.
“Additionally, it explains how a process might work in a controlled lab condition rather than real-world eating behaviors,” she added as a limitation. “Finally, the study is short-term and doesn’t give us the long-term translation on lifespan outcomes.”
The review found intermittent fasting was barely more effective than doing nothing, according to the study authors. (iStock)
Wright cautioned that fasting is “not a magic solution for longevity, and how you eat overall matters more than when you eat.”
“I advise, first and foremost, to focus on diet quality, including a variety of fruits and vegetables, healthy fats and minimally processed foods,” she said.
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For those who are considering fasting, it’s better to stick with a moderate plan — like a 12- to 14-hour overnight fast — rather than going to extremes, Wright said. After fasting, she recommends focusing on well-balanced meals.
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Several groups of people should be cautioned against fasting, according to Wright, including those with diabetes who are on insulin or hypoglycemic medications, those who are pregnant or breastfeeding, anyone with a history of eating disorders and older adults at risk of malnutrition.
Anyone considering intermittent fasting should consult with a doctor before starting.
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