Health
4 troubling cancer trends you must know about in 2025
The American Cancer Society’s annual cancer trends report revealed a mix of news and statistics for 2025.
Cancer death rates have dropped 34% between 1991 and 2022, which the ACS attributes to early detection, smoking reduction and improvements in treatment.
While these numbers are encouraging, oncologists and cancer specialists still have concerns about some other factors.
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While the report shows continued progress on many fronts, certain areas remain of “significant concern,” Dr. Joshua Strauss, an attending hematologist and medical oncologist at Advanced Care Oncology and Hematology Associates of the Atlantic Medical Group in Morristown, New Jersey, shared with Fox News Digital.
Oncologists share which cancer trends most concern them for 2025. (iStock)
Below are some of the most concerning trends, according to experts.
1. Cancer deaths not improving in younger individuals
Cancer prevalence in younger individuals and adolescents has continued to rise, according to the report, with rates in teens slowly increasing by 0.7% each year.
Cancer is the leading disease-related cause of death among children and adolescents — most commonly leukemia, brain cancer and lymphoma.
In 2025, the ACS estimates that 9,550 kids up to 14 years old and 5,140 adolescents aged 15 to 19 will be diagnosed with cancer, and that 1,050 children and 600 adolescents will die.
Cancer is the leading disease-related cause of death among children and adolescents, according to ACS. (iStock)
Dr. Paul Oberstein, a gastrointestinal medical oncologist and section chief of GI Medical Oncology at NYU Langone Perlmutter Cancer Center, reiterated that people below age 50 are seeing higher rates of cancer deaths.
“It’s shown in multiple cancers,” he told Fox News Digital. “I would say the biggest finding is in young women with breast cancer.”
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The prevalence of GI (gastrointestinal) cancers is also increasing among younger adults, including pancreatic and colon cancer.
Experts have varying hypotheses on why young people are being diagnosed more often, including diet, exposure to microplastics or other environmental triggers, according to Oberstein.
One medical oncologist pushed for more research across patients and institutions to “figure out what’s going on.” (iStock)
“We don’t have a good explanation, and we need to invest in discovering why this might be the case so that we can change it,” he said.
2. Cervical cancer continues to pose unnecessary threat
Cervical cancer is one of the few cancers that can be prevented, yet thousands of women are still at risk.
While cervical cancer incidence rates decreased by more than half from the mid-1970s to the mid-2000s due to screening uptake, these numbers have since stabilized, according to the report.
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A projected 13,000 women will be diagnosed with cervical cancer in 2025 and 4,000 will die, according to Dr. Jessica Shepherd, a board-certified obstetrician gynecologist in Dallas, Texas.
Cervical cancer risk and rates of mortality correlate to connectivity with a healthcare provider, one expert said. (iStock)
“Cervical cancer in women from 30 to 44 is increasing,” she told Fox News Digital. “But also, this is a cancer that has the potential to be eradicated, if not eliminated, because of us knowing the understanding of HPV and its prevalence in the disease.”
HPV (human papillomavirus infection), the most common cause of cervical cancer, can be detected through testing.
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“We have innovation and technology that should be decreasing certain cervical cancer rates,” Shepherd said.
3. Some communities lack healthcare access
The ACS report found that Native Americans and Black people continue to die at higher rates than White people for several different cancers.
Among cervical cancer patients, the death rate in Black women and Native American women is 50% and 70% higher than in white women.
The five-year relative survival rate for cervical cancer in Black women is 58% compared to 67% of White women, the report found.
Black women are 50% more likely to die from cervical cancer than White women, the report found. (iStock)
This discrepancy in mortality rate is most likely due to lack of access to doctors and regular screenings, added Shepherd, who pushed for more research, awareness and public education.
“Cervical cancer is preventable through screening with the Pap plus HPV and co-testing,” she said. “If we had the ability to have more potential early detection, then we could see abnormalities in cells … before it actually gets to cancer and could take the time to address it.”
4. GI cancer diagnoses are worsening
Gastrointestinal (GI) cancers, such as pancreatic, liver, colorectal and stomach cancers, are all considered highly deadly.
The ACS report noted that colorectal diagnoses in men and women under the age of 65 have continued to increase.
Between 2012 and 2021, colorectal cancer incidence rates increased by 2.4% each year in people younger than 50 and by 0.4% per year in adults 50 to 64.
Colorectal cancer diagnoses in men and women under the age of 65 have continued to increase, according to ACS. (iStock)
Progress against pancreatic cancer is also trailing other cancers, according to the report, as incidence and mortality rates increase by 1% each year in men and women.
The ACS noted that in 2025, an estimated 67,440 new cases of pancreatic cancer will be diagnosed in the U.S. and 51,980 people will die from it.
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The death rate for pancreatic cancer has increased by 0.2% to 0.3% each year in men and women, and the five-year relative survival rate is 13%, which Strauss described as “dismal.”
Oberstein, a GI specialist, noted that these types of cancers “often have very poor outcomes,” although there have been some improvements in early detection and treatment over the last few decades.
Gastrointestinal cancers “often have very poor outcomes,” one oncologist cautioned. (iStock)
“The biggest benefit we’ve seen in terms of mortality comes from earlier detection of GI cancers,” he told Fox News Digital, adding that colon cancer has the best outcomes when detected early.
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“But we really need to double down on trying to detect stomach cancer, liver cancer and especially pancreatic cancer earlier in order to make a big difference,” Oberstein said.
Fox News Digital’s Melissa Rudy contributed to this report.
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An accidental lab discovery has opened the door to entirely new ways of preventing the flu.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells, SWNS reported.
By targeting the specific molecules the viruses rely on, scientists found that they could block them from entering new cells and halt their replication altogether.
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Researchers say these “fundamental insights” into seasonal influenza highlight a clear path toward developing better preventive medications.
“The hope is that fundamental, curiosity-based research like this helps to pave the way for novel strategies to treat and prevent influenza infections,” principal investigator Dr. Emily Bruce, from the University of Vermont’s Larner College of Medicine, said in the SWNS report.
While investigating how influenza replicates, researchers discovered that different flu strains use completely different strategies to infiltrate human cells. (iStock)
While several flu strains cause illness, H1N1 and H3N2 influenza A viruses are the most common. However, current flu tests cannot differentiate between them, and clinical treatments are identical for both.
Although vaccines and antivirals are available, Bruce noted a “dire” need for better medications to stop the virus from spreading cell to xxcell.
“You don’t get sick when a virus is in one cell,” he noted. “You get sick because a virus replicates itself and goes into many more cells.”
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The study, which was published in The Journal of Virology, originally aimed to map how viral RNA segments are transported within cells to create new viral particles.
The team used H1N1 and H3N2 viruses isolated from the nasal passages of positive patients in 2022.
Clinical treatments remain identical for both primary strains of the flu virus. (iStock)
During the investigation, the team unexpectedly stumbled upon a cellular pathway that blocked the virus from entering lung cells, SWNS reported.
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The data revealed that when a specific human protein called Rab11B was depleted, H3N2 viruses failed to enter human lung cells. H1N1 viruses were completely unaffected.
Using reverse genetics, the team mapped this defect and uncovered a brand-new, H3N2-specific role for Rab11B during viral entry.
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This discovery challenged the scientific assumption that all flu viruses enter cells the same way.
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“Viruses are like pirates from different countries hijacking someone’s ship,” Bruce said. “Different viruses, like different types of pirates, use different methods to get onboard.”
This discovery challenged the scientific assumption that all flu viruses enter cells the same way. (iStock)
“We had previously thought that all flu viruses used the same way to get into a cell, but we discovered that this is not true,” she went on. “H1N1 and H3N2 need different proteins to get in, and if you get rid of the right protein, a specific virus can’t get in.”
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While these findings identify a critical cellular pathway for viral entry, the study was conducted using isolated cells, the researchers acknowledged.
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Further research is needed to determine whether blocking the protein is safe and effective within a live, complex human respiratory system.
Bruce and the team hope to conduct further research to determine whether this Rab11B-dependency is a fundamental property of H3N2, or if it’s a trait unique to currently circulating flu strains.
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Eating processed meat like ham, sausage and bacon may be linked to a higher risk of certain types of cancer, according to new research.
While health organizations have already confirmed that processed meat can contribute to colon cancer, this study looked closer at cancers in the upper digestive tract, where the link has historically been less clear.
To understand these connections, researchers from the European Prospective Investigation into Cancer and Nutrition (EPIC), one of the world’s largest long-term nutrition and cancer cohorts, tracked the health and diets of 450,112 people across Europe for an average of 14 years.
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The study group included 131,426 men and 318,686 women, according to the study’s press release.
During the follow-up period, 876 people developed stomach cancer and 215 people developed esophageal adenocarcinoma, which is cancer of the tube connecting the mouth to the stomach.
For female participants, eating both processed meat and white meat was linked to an increased risk of developing the disease. (iStock)
Researchers tracked where the stomach cancers grew, separating them into the upper part of the stomach near the throat and the lower part of the stomach.
The researchers also sorted the tumors into two categories based on how the cancer cells appeared under a microscope: intestinal, which forms more organized structures, and diffuse, in which the cells are more scattered throughout the tissue.
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After adjusting for other lifestyle factors, the researchers found that for every extra 30 grams of processed meat a person ate per day, their overall risk of stomach cancer went up by 9%. Eating that same extra 30 grams a day was also linked to a 13% higher risk of esophageal adenocarcinoma.
A standard single slice of regular deli-sliced ham or lunch meat averages around 28 grams, according to USDA data and nutritional tracking databases.
An extra 20 grams of white meat, such as chicken and turkey, was linked to a 12% higher risk of cancer in the main body of the stomach. (iStock)
An extra 20 grams of white meat, such as chicken or turkey, was linked to a 12% higher risk of cancer in the main body of the stomach, the researchers noted.
The study also revealed differences between men and women. For male participants, only processed meat showed a clear, statistically significant link to a higher risk of stomach cancer. For female participants, however, eating both processed meat and white meat was linked to an increased risk.
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These findings align with global health benchmarks, particularly those established by the World Health Organization’s International Agency for Research on Cancer.
The agency has long classified processed meat as a known human carcinogen, primarily due to its strong, well-documented links to colorectal cancer.
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However, health organizations have also consistently pointed to a potential, yet less definitive, relationship between these meats and cancers of the stomach.
Eating 30 grams of processed meat a day, or the equivalent to one slice of ham, was linked to a 13% higher risk of esophageal adenocarcinoma. (iStock)
Further scientific investigation is needed to confirm the findings and to account for other underlying risk factors, such as certain stomach infections, which could interact with dietary habits.
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A key limitation of the study is its reliance on self-reported diets, which can sometimes lead to inaccuracies in how participants recall their meat consumption over time, the researchers noted.
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The findings were published in the International Journal of Cancer.
Fox News Digital reached out to the researchers requesting comment.
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