Connect with us

Fitness

Next-generation fitness: New fields promise personalized exercise recommendations

Published

on

Next-generation fitness: New fields promise personalized exercise recommendations
Enduromics and resistomics are emerging disciplines that examine unique molecular adaptations to endurance and resistance training in a large population. Credit: Professor Katsuhiko Suzuki / Waseda University

Exercise has been recognized as an extremely effective tool to improve human health—it can have a preventative and even therapeutic effect on non-communicable diseases such as diabetes and cardiovascular diseases.

By promoting physical activity not only among athletes, but also among the general population, several non-communicable diseases can be prevented, eventually reducing the financial burden upon the health care system.

However, the exact changes that occur at a molecular level due to different types of exercise have not been explored thoroughly. One reason for this is that, traditionally, collecting molecular information (such as metabolite data) required invasive tissue or muscle biopsies, limiting the scale of studies that could be performed.

Now, in a study published in Sports Medicine—Open, Dr. Kayvan Khoramipour from Miguel de Cervantes European University, along with other co-authors, and Professor Katsuhiko Suzuki from the Faculty of Sport Sciences, Waseda University, Japan, introduce and review literature in two emerging fields that could advance our understanding of exercise physiology in humans.

Advertisement

These disciplines use “multi-omics” data, or data from multiple sets of biological molecules (such as proteins, metabolites, or even RNA). Prof. Suzuki and his colleagues have termed these fields as “resistomics” and “enduromics.”

The authors explain that enduromics and resistomics are fields that examine the molecular changes induced by endurance and resistance training, respectively. While endurance training is what we might refer to as aerobic exercise (that increases your breathing and heart rate), resistance training involves improving your muscle strength.

To better explain these two terms, Prof. Suzuki further elaborates that, “Enduromics and resistomics examine unique molecular adaptations to endurance and resistance training in a larger population, as opposed to the field of ‘sportomics,’ which focuses on molecular alterations in competitive athletes.”

More specifically, enduromics reveals the biological pathways involved in processes such as lipid metabolism, generation of new mitochondria, and aerobic efficiency, or your body’s ability to effectively use oxygen—all of which adapt and change in response to moderate-to-intense aerobic exercise.

On the other hand, resistomics specifically focuses on muscle hypertrophy or muscle growth, synthesis of new proteins, and neuromuscular adaptations in the body. These fields can identify the biomarkers and metabolic fingerprints, aiding in understanding how specific metabolic states differ between individuals.

Advertisement

Taken together, both resistomics and enduromics can give us a clear picture of the molecular adaptations that arise in different individuals in response to both resistance and endurance training.

Emphasizing the practical applications of enduromics and resistomics, Prof. Suzuki explains, “By utilizing molecular profiling, these disciplines pave the way for personalized exercise prescriptions, using molecular insights to tailor training to an individual.”

He adds that these personalized training plans can enhance fitness and rehabilitation while reducing injury risks for both athletes as well as the general population. The team also believes that by transitioning the focus from athletes to the general population, the collective health of society can be strengthened.

In the long term, Prof. Suzuki and his colleagues would like to discover molecular mechanisms underpinning adaptation to exercise, which could even prove helpful for disease prevention and treatment.

More information:
Kayvan Khoramipour et al, From Multi-omics To Personalized Training: The Rise of Enduromics and Resistomics, Sports Medicine – Open (2025). DOI: 10.1186/s40798-025-00855-4

Advertisement
Provided by
Waseda University

Citation:
Next-generation fitness: New fields promise personalized exercise recommendations (2025, June 11)
retrieved 11 June 2025
from https://medicalxpress.com/news/2025-06-generation-fields-personalized.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Advertisement

Fitness

Do you have sore hips? I asked a pain specialist why this happens and how to improve it

Published

on

Do you have sore hips? I asked a pain specialist why this happens and how to improve it

Hip soreness is a terribly common issue—it’s something that I certainly suffer with—so I’m always trying to get to the bottom of where this soreness originates from and what you can do about it.

According to Dr Shady Hassan, MD, an interventional pain and sports medicine physician and the founder of NefraHealth, immobility is the root cause of this discomfort.

Advertisement
Continue Reading

Fitness

“No Pain No Gain” May Be Wrong: Science Says Slow Eccentric Exercise Builds Stronger Muscles

Published

on

“No Pain No Gain” May Be Wrong: Science Says Slow Eccentric Exercise Builds Stronger Muscles

Modern exercise culture has spent years glorifying exhaustion. The harder a workout feels, the more effective people assume it must be. Sore muscles became badges of honor, while gentle movements were often dismissed as ‘not real exercise.’ 

A man lifting a dumbbell. Image credits: Andres Ayrton/Pexels

However, according to a new study, some of the most efficient ways to build muscle strength may happen during the slow, controlled moments people usually ignore—walking downstairs, lowering weights, or carefully sitting into a chair. 

Study author Kazunori Nosaka, who is the director of exercise and sports science at Edith Cowan University, argues that eccentric exercise—a type of muscle action that occurs while muscles lengthen under tension, may offer a more practical alternative. Its opposite, concentric exercise, is the shortening (lifting) phase where muscles produce force to overcome resistance.

Instead of demanding maximum effort, these movements appear to train muscles while placing less stress on the body.  

“The idea that exercise must be exhausting or painful is holding people back. Instead, we should be focusing on eccentric exercises which can deliver stronger results with far less effort than traditional exercise – and you don’t even need a gym,” Nosaka said.

Muscles work differently on the way down

The study examines decades of earlier research on eccentric exercise rather than presenting a single laboratory experiment. It focuses on a simple but often overlooked detail of human movement, which is how muscles behave differently depending on whether they are shortening or lengthening.

Advertisement

When someone lifts a dumbbell, climbs stairs, or rises from a chair, muscles shorten as they generate force. Scientists call this a concentric contraction. Eccentric contractions happen during the opposite phase—when the muscle stays active while stretching. 

Examples include lowering the dumbbell back down, descending stairs, or slowly lowering the body into a seated position. According to the review, muscles can tolerate and produce greater force during eccentric actions while using comparatively less energy and oxygen. 

“Eccentric contractions are distinguished by their ability to generate greater force than concentric or isometric contractions, while requiring less metabolic cost,” Nosaka notes.

Researchers believe this happens because muscles act more like controlled braking systems during lengthening movements, resisting gravity rather than directly overpowering it. As a result, people may gain strength without putting the same level of demand on the cardiovascular system. 

This difference could make eccentric exercise especially useful for individuals who find traditional workouts physically overwhelming.

“Eccentric exercise training provides numerous benefits for physical fitness and overall health, making it suitable for a wide range of individuals from children to older adults, clinical populations to athletes, and sedentary to highly active people,” Nosaka added.

Gravity may be doing more training than we realized

To support this argument, the study brings together findings from several earlier research works. For instance, one study from 2017 tracked elderly women with obesity who repeatedly walked either upstairs or downstairs over a 12-week period. 

While climbing stairs is normally considered the tougher workout, the women assigned to walk downstairs showed stronger improvements in measures including blood pressure, heart rate, and physical fitness. The results suggested that resisting gravity during downward movement may provide a surprisingly powerful training effect.

YouTube videoYouTube video

The review also discusses eccentric cycling, where participants resist pedals driven backward by a motor instead of pushing them forward in the usual way. 

Although the movement feels unusual and requires concentration, earlier studies found it improved muscle power, balance, and cardiovascular health while feeling less exhausting than standard cycling workouts.

Another important part of the review addresses muscle soreness, one of the main reasons eccentric exercise never became widely popular outside rehabilitation settings. People often experience delayed onset muscle soreness, or DOMS, after unfamiliar eccentric workouts. 

Advertisement

“Unaccustomed eccentric exercise is often associated with muscle damage characterized by delayed onset muscle soreness (DOMS) and a reduction in muscle force-generating capacity lasting more than a day. However, this effect diminishes or at least is attenuated when the same eccentric exercise is repeated (known as the repeated bout effect),” Nosaka explained

Many eccentric exercises require little or no equipment. Slow squats into a chair, heel-lowering movements, controlled wall push-ups, or even maintaining posture against gravity can activate eccentric muscle work. 

Moreover, some studies referenced in Nosaka’s review suggest that just a few minutes of these exercises each day can still produce measurable improvements in health and strength.

The future of fitness may feel less punishing

The findings challenge the mindset surrounding fitness itself. Many people abandon exercise routines because they associate physical activity with pain, fatigue, or lack of time. Eccentric exercise suggests that effective movement does not always need to feel extreme. 

If future research continues to support these findings, eccentric exercise could influence far more than gym routines. It may reshape physical rehabilitation, elderly care, injury recovery programs, and public-health recommendations aimed at increasing physical activity among sedentary populations. 

These exercises also place lower demands on the heart and lungs while still strengthening muscles. They could help people who are unable or unwilling to follow intense training programs.

Advertisement

Nosaka suggests that “we should establish eccentric exercise as standard practice, and make it common, accessible, and widely accepted as the ‘new normal’ of exercise to improve life performance and high (athletic) performance.”

However, this does not mean eccentric exercise is a universal replacement for all forms of physical activity. The current paper is a review of previous studies, and its findings still need to be validated through experiments and large-scale clinical trials.

Nosaka also notes that “Future studies should investigate mechanisms underpinning the effects of eccentric exercises in comparison to other types of exercises (e.g., isometric exercises, concentric exercises, aerobic exercises),”  

This could help scientists design safer and more personalized exercise programs for different age groups and health conditions.

The study is published in the Journal of Sport and Health Science.

Advertisement
Continue Reading

Fitness

Flexibility expert recommends doing this for three minutes daily to improve mobility

Published

on

Flexibility expert recommends doing this for three minutes daily to improve mobility

Longevity is something of a buzzword right now, and the idea of living better for longer is undoubtedly appealing. Mobility is a key component of this.

By definition, mobility is the ability to move freely, something that tends to deteriorate as we age. But there are simple things we can do to maintain it.

One of them is “joint flossing”, a daily practice recommended by experienced coach and mobility specialist Darren Ellis.

“Mobility is a conflation of strength and flexibility,” he says. “I always used to believe that strength was the foundation of everything in exercise. But if you’re strong and you can’t move through a decent range of motion at certain joints, you’re still suffering.

“When you reach down to pick something up from the floor and it seems further away than it used to be, you suddenly realise how crucial mobility is.”

Advertisement

Below, Ellis explains how to use his three-minute joint flossing protocol to help ease stiff joints and improve your ability to move.

How to try joint flossing

The body works on a rough “use it or lose it” basis. If you rarely move a joint through its full range of motion, the tissues around it can become tight, stiff and sore. The natural remedy for this is gradually reintroducing movement in the affected areas.

“The easiest place to start when improving mobility is to get the joints moving more freely with some simple joint circles,” says Ellis. “I sometimes call it joint flossing because, firstly, you are flossing nutrients through the joint by promoting blood flow in this area, and secondly, it’s something you should do regularly.”

Advertisement

You start with neck circles then work your way down your body from your head to your toes, as shown in the video above – if something can move, you move it.

Ellis recommends doing five to 10 repetitions per body part, using a controlled tempo and a range of motion that feels safe and comfortable for you.

“There’s no need to force anything,” he says. “You’re just giving your body a chance to move again.”

Doing this consistently will improve your physical capacity and mobility, allowing you to return to other movements and exercises over time.

Read more: Five stretches you should be doing every day, according to a flexibility expert

Advertisement

Continue Reading
Advertisement

Trending