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Ozempic’s health benefits keep growing, but are the risks worth it?

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Ozempic’s health benefits keep growing, but are the risks worth it?

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One in eight adults in the U.S. has taken Ozempic or another type of GLP-1 drug, surveys show — and now a major new study has revealed a long list of benefits and some little-known risks.

Glucagon-like peptide-1 receptor (GLP-1) agonists — which contain either semaglutide or liraglutide — are prescribed to treat type 2 diabetes and obesity, but previous studies have linked the drugs to other, unexpected benefits.

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Researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs (VA) St. Louis Health Care System studied the health outcomes of more than two million veterans with diabetes who took Ozempic or another type of GLP-1 drug between Oct. 1, 2017 and Dec. 31, 2023, according to a university press release.

OZEMPIC ‘MICRODOSING’ IS THE NEW WEIGHT-LOSS TREND

They then compared those outcomes to veterans who took non-GLP-1 diabetes medications.

One in eight adults in the U.S. has taken Ozempic or another type of GLP-1 drug, surveys show. (iStock)

The study, published in the journal Nature on Jan. 20, identified “widespread associations” between Ozempic and some significant health benefits.

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Those benefits included reduced risks of neurocognitive disorders like Alzheimer’s and dementia, seizures, and addiction to harmful substances such as alcohol, cannabis, stimulants and opioids.

Other positive health effects included lower risks of suicidal ideation, self-harm, bulimia and psychotic disorders such as schizophrenia.

OZEMPIC COULD HELP REDUCE ALZHEIMER’S RISK FOR SOME, STUDY SUGGESTS: ‘SHIFTING THE PARADIGM’

“GLP-1s have many benefits for at least 42 conditions beyond weight loss – from addiction disorders to memory/cognition problems, blood clots, and infections,” lead study author Ziyad Al-Aly, clinical epidemiologist at Washington University in St. Louis, told Fox News Digital.

Ozempic and other GLP-1 drugs act on receptors in the brain that are involved in impulse control, reward and addiction, Al-Aly noted, which could explain why they are effective in reducing cravings for food and addictive substances.

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“GLP-1s have many benefits for at least 42 conditions beyond weight loss.”

“These drugs also reduce inflammation in the brain and result in weight loss; both of these factors may improve brain health and explain the reduced risk of conditions like Alzheimer’s disease and dementia,” he added.

They also found, however, that GLP-1 drugs were linked to several adverse side effects.

Novo Nordisk is the maker of Ozempic, which is approved for type 2 diabetes treatment and reduced risk of cardiovascular events. (Getty Images)

The risk of gastrointestinal problems — including nausea, vomiting, diarrhea and a rarer paralysis of the stomach — were widely known before this new study, the researcher noted.

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The new finding, however, was that these drugs can negatively affect the pancreas and kidneys. They were also linked to a higher chance of developing arthritis.

DIABETES AND WEIGHT LOSS DRUGS SHOWN TO REDUCE ALCOHOL-RELATED HOSPITALIZATIONS, STUDY FINDS

“While these adverse effects are uncommon, they can be very serious; physicians must be vigilant for signs of pancreatitis (inflammation of the pancreas) and monitor kidney function among people taking GLP-1RA medications,” Al-Aly stated in the press release. 

“Kidney problems can occur without symptoms until the condition is at an advanced stage with limited treatment options.”

Decreased obesity has long been linked with less inflammation in every body system, an expert pointed out.  (iStock)

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The study, which was funded by the U.S. Department of Veterans Affairs, did have some limitations, the researchers acknowledged. 

“This is a discovery approach involving more than two million people and is not a randomized trial,” Al-Aly told Fox News Digital.

“People with real weight loss are happier overall — they feel empowered.”

Seth Kipnis, MD, medical director of bariatric and robotic surgery at Hackensack Meridian Jersey Shore University Medical Center, was not involved in the study but said it confirms what he has seen in his own clinical practice.

“People with real weight loss are happier overall — they feel empowered that they can finally control their weight,” he said in a statement sent to Fox News Digital.

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The risk of gastrointestinal problems — including nausea, vomiting, diarrhea and a rarer paralysis of the stomach — were widely known before this new study. (iStock)

Decreased obesity has long been linked with less inflammation in every body system, Kipnis pointed out. 

“GI problems and renal problems will always be seen if people are not eating correctly and maintaining hydration,” he said. “If you take these medications without nutritional education, they can be harmful.”

Recommendations and predictions

Based on the findings, the researchers noted, people should be aware that these drugs have not only a “broad beneficial profile,” but also important risks. 

“People should use the information to discuss with their provider whether GLP-1 is the right medication for them,” Al-Aly recommended. 

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“A person with a lot of GI issues may find these meds intolerable.”

“A person who is trying to lose weight and quit smoking or drinking may find GLP-1s especially useful – helping hit two birds with one stone — but a person with a lot of GI (gastrointestinal) issues may find these meds intolerable,” he went on.

“Each person’s health profile is different. Pros and cons should be discussed with the provider.”

CHEAP OZEMPIC KNOCK-OFFS HAVE RISEN IN POPULARITY

Given their effectiveness at causing weight loss and improving health, GLP-1 drugs will likely become more common and increase in use, Hackensack’s Kipnis predicted.

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“We have been prescribing many long-term drugs for hypertension, heart disease, high cholesterol, diabetes, arthritis, reflux and many other diseases without hesitation,” he said.

The new study revealed that GLP-1 drugs could negatively affect the pancreas and kidneys.  (iStock)

“This new class of drug, as it lowers obesity, has the potential to lower the use of every other drug that is used to treat obesity-related conditions.”

Not every doctor should prescribe these medications, however, according to Kipnis.

“Doctors with weight management programs and nutrition education programs would likely have better outcomes and fewer side effects,” the doctor said.

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Novo Nordisk, the maker of Ozempic (approved for type 2 diabetes treatment and reduced risk of cardiovascular events) and Wegovy (approved for weight management and reduced risk of cardiovascular events), provided the following statement to Fox News Digital.

      

 “Semaglutide has helped millions of people fight chronic diseases such as type 2 diabetes, cardiovascular disease and obesity. As we look to help even more people with chronic diseases, we are exploring the potential of semaglutide in several other disease states.”

Wegovy, also made by Novo Nordisk, is FDA-approved for weight management and reduced risk of cardiovascular events. (Steve Christo – Corbis/Corbis via Getty Images)

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“Patient safety is of utmost importance to Novo Nordisk. The known risks and benefits of semaglutide medicines are described in their FDA-approved product labeling and we work closely with authorities and regulatory bodies worldwide to continuously monitor the safety profile of our products.”

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The company added that the “totality of data” from previous studies “provides reassurance of the safety profile of semaglutide.”

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Seniors over 80 who eat specific diet may be less likely to reach 100 years old

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Seniors over 80 who eat specific diet may be less likely to reach 100 years old

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Older adults who avoid meat in their golden years may be less likely to reach age 100 than their meat-eating counterparts, new research suggests.

Researchers tracked more than 5,000 adults aged 80 or older who were enrolled in the Chinese Longitudinal Healthy Longevity Survey.

Between 1998 and 2018, data showed that those who did not eat meat were less likely to reach their 100th birthday than those who consumed animal products regularly.

The findings seem to contradict previous studies that have linked vegetarianism and plant-based diets to lower risks of heart disease, stroke, diabetes and obesity.

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Most evidence supporting the benefits of plant-based diets comes from studies tracking younger populations, the researchers noted. 

The findings contrast with previous research praising plant-based diets for their positive influence on heart health. (iStock)

The study, published in The American Journal of Clinical Nutrition, points to losses in muscle mass and bone density with age, shifts that can increase the risk of malnutrition and frailty in the “oldest old.”

As people enter their 80s and 90s, the nutritional priority often shifts from preventing long-term chronic diseases to maintaining day-to-day physical function, experts say.

HOW MUCH RED MEAT IS TOO MUCH? EXPERTS WEIGH IN ON FOOD PYRAMID UPDATES

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“The headline ‘vegetarians over 80 less likely to reach 100’ sounds surprising, because it contrasts with decades of data linking plant‑forward diets to lower chronic disease risk earlier in life,” Erin Palinski-Wade, a New Jersey-based registered dietitian, told Fox News Digital. 

“However, once you see that this research is limited to adults over the age of 80 who are also underweight — and that this link disappears with the consumption of eggs, dairy and fish — the results are less surprising.”

While diets earlier in life tend to emphasize avoiding long-term disease, older age necessitates nutrients and weight maintenance, experts say. (iStock)

In those over 80, restricting animal proteins may be less likely to promote longevity, according to Palinski-Wade, who was not involved in the study.

Eliminating all animal protein — particularly in a population that may already experience diminished hunger cues — can make it more difficult to meet adequate protein needs, potentially increasing the risk of nutrient deficiencies, the nutritionist said.

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ALZHEIMER’S SYMPTOMS COULD BE PREDICTED YEARS IN ADVANCE THROUGH ONE SIMPLE TEST

In addition to a higher tendency to be underweight, older populations also face a greater risk of bone fractures due to lower calcium and protein intake.

Potential limitations

The lower rate of vegetarians reaching 100 was only observed in participants identified as underweight, the researchers noted. No such association was found in people who maintained a healthy weight.

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Because being underweight is already linked to greater frailty and mortality risk, the researchers noted that body weight may partly explain the findings, making it difficult to determine whether diet itself played a direct role.

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Those incorporating animal-sourced products other than meat were just as likely to live to 100. (iStock)

Additionally, the shortened lifespans were not found in people who continued to eat non-meat animal products, such as fish, dairy and eggs. 

Older adults with these more flexible diets were just as likely to live to 100 as those eating meat, as these foods may provide the nutrients necessary for maintaining muscle and bone health, the researchers noted.

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“This is an observational study, so it can only show associations, and does not prove that avoiding meat directly reduces the odds of reaching 100,” Palinski-Wade added.

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The researchers suggested that including small amounts of animal-sourced foods could help older seniors maintain essential nutrients and avoid the muscle loss often seen in those who stick strictly to plants.

Eliminating all animal protein — particularly in a population that may already experience diminished hunger cues — can make it more difficult to meet adequate protein needs, potentially increasing the risk of nutrient deficiencies. (iStock)

Palinski-Wade offered some guidance for those looking to optimize nutrition later in life.

“For adults in their 80s and beyond, especially anyone losing weight or muscle, the priority should be maintaining a healthy weight and meeting protein and micronutrient needs — even if that means adding or increasing fish, eggs, dairy or well‑planned, fortified plant proteins and supplements.”

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Strict vegan or very low‑protein patterns at that age should be carefully monitored by a dietitian or clinician, with attention to B12, vitamin D, calcium and total protein, according to Palinski-Wade.

“Younger and healthier adults can still confidently use plant‑forward or vegetarian patterns to lower long‑term chronic disease risk,” she added.

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The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s

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The Latest on Natural Ozempic Alternatives: How To Lose Weight Without GLP-1s


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Natural Ozempic Alternatives That Boost GLP-1 for Weight Loss | Woman’s World




















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Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

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Punch the monkey, viral star, experiences dramatic breakthrough among zoo mates

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In a dramatic turn of events that’s captured the attention of animal lovers worldwide, Punch — the young macaque at a zoo in Japan famous for his inseparable bond with a stuffed orangutan toy — has reached a major milestone in his journey toward social integration.

On Thursday, visitors and staff at the Ichikawa Zoological and Botanical Garden witnessed a breakthrough: Punch was seen cuddling with and hitching a ride on the back of a fellow macaque.

Punch’s story began with hardship. He was abandoned by his mother shortly after his birth in July 2025 — and to ensure his survival, zookeepers stepped in to hand-rear the primate.

On Jan. 19, 2026, the zoo officially began the process of reintegrating Punch into the “monkey mountain” enclosure.

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The transition was initially fraught with tension. 

Punch’s story began with hardship when he was abandoned by his mother shortly after he was born. To help him, zookeepers gave him a stuffed toy that he began dragging around everywhere he went.  (David Mareuil/Anadolu via Getty Images)

As a hand-reared infant, Punch was bullied and ignored by the established group of monkeys.

He was often seen huddled alone with his orange plush companion while the rest of the troop interacted.

BABY MONKEY CARRIES FAITHFUL STUFFED COMPANION EVERYWHERE HE GOES, DRAWING CROWDS AT ZOO

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In an official statement released Feb. 27, the Ichikawa Zoological and Botanical Garden detailed the meticulous care behind this process.

Previous viral videos showed Punch bullied by the rest of the troop, running to his plushy toy for comfort. (David Mareuil/Anadolu via Getty Images)

“From an animal welfare perspective, our primary goal is to reintegrate Punch with the troop,” the zoo said. 

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The strategy involved nursing Punch within the enclosure, so the troop could recognize him as one of their own, and pairing him with a gentle young female macaque prior to his full release to build his confidence.

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The latest footage, captured by X user @tate_gf, suggested the zoo’s patience is paying off. 

The video shows Punch seeking physical contact not from his toy, but from another monkey — eventually climbing onto its back for a vital social behavior for young macaques: the “piggyback ride.”

The zoo’s strategy appears to be paying off: Punch, shown at far left, was recently seen riding on the back of a fellow macaque. (David Mareuil/Anadolu via Getty Images)

While Punch still carries his stuffed toy for comfort during moments of perceived danger, the zoo remains optimistic about his progress. 

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The organization cited the successful 2009 case of Otome, another hand-reared macaque who eventually outgrew her stuffed toy, successfully integrated — and went on to raise four offspring of her own.

The zoo has had crowds coming to see Punch, with hundreds of people lining up to get inside to see the young star, according to reports. 

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“I’m hoping Punch has a good life like everybody else does, and think he’s a cute little guy,” one person commented online. 

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“Such a precious baby,” another person wrote. 

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