San Diego, CA
Boston Micro Fabrication Launches Spinout in San Diego – San Diego Business Journal
SAN DIEGO – Precision micro-printing provider Boston Micro Fabrication (BMF) has launched San Diego-based BMF Biotechnology Inc., a spinout dedicated to making specialized chips through cultivated large-scale tissues in vitro, helping accelerate new drug and cosmetic development.
Chief Scientific Officer
BMF Biotechnology Inc.
“BMF Biotechnology’s BioChips allow scientists to grow human-like tissues in a lab setting and because these chips mimic how substances would be processed inside the body, scientists can use them to test drugs and cosmetic products,” BMF Biotechnology Chief Scientific Officer Jennifer Sun told the Business Journal.
“These microfluidic chips are an organ-on-a-chip platform, which can replicate the physiological conditions found in the human body by controlling the flow of small amounts of fluid through micro-size channels.”
Founded in 2016, BMF says it supports more than 2,000 customers globally with offices in Boston, China, Japan and now in San Diego.
“BMF has raised over $80M in investment funding, including $24M in 2023,” added Sun. “We have over 250 employees worldwide with global revenue growth exceeding 30% in 2023.”
Wanting to be housed in San Diego’s vibrant biotech ecosystem, the company’s San Diego Research Institute was born in 2022. The newly launched biotech division will operate out of Carroll Canyon with ten or so employees to start.
Preliminary feedback has yielded promising results, says BMF.
“Specifically, significant progress has been made in terms of developing functional prototypes of the BMF Biotechnology’s BioChip, validating their efficacy in replicating human tissue models accurately,” shared Sun. “Furthermore, preliminary tests have shown encouraging outcomes of disease modeling and validating human drug responses.”
BMF is entering an arena of competitors like MIMETAS and InSphero – working to commercialize organ-on-a-chip technology. Sun says its product stands apart.
“Our BioChip platform offers distinctive features, including a micro-channel network designed to mimic blood vessels with micron level three dimensional features. This network ensures efficient nutrient delivery and waste removal throughout the chip, enabling the comprehensive replication of human tissues on a large scale.”
Hybrid Printing Solution
In recent years, micro molding and 3D printing innovations have swept the micro-manufacturing world, advancing how production companies do business.
New England-based BMF’s core tech enables highly precise, micro-scale 3D printing across industries like healthcare, life sciences, electronics and machining.
“3D printing has often been known for its ability to rapidly iterate on product design, but this same benefit can also be applied to developing custom, high-precision solutions that advance research in other ways – such as through pharmaceutical development,” said Sun. Now the industry is trending toward miniaturization. “As products and technology get smaller, the connective parts become micro and more intricate. There is an urgent need for highly precise and accurate manufacturing methods that allow engineers and product designers to consistently create small-scale parts with the precision, resolution and accuracy needed to move industries forward.”
This month, BMF announced what it calls the industry’s first line of hybrid printing solutions for micro-scale and ultra high-resolution applications that allow the user to print two resolutions within a single layer or in different layers.
CEO-Global
BMF
“Our driving motivation for innovation has been to offer new platforms that can help realize high-value applications for 3D printing,” said BMF CEO-Global John Kawola. “Increasingly, we have been pushed by our customers to bring our technology to applications where higher precision and tighter tolerances would result in an overall increase in quality and performance, regardless of part size.”
It comes after another big win for the company. Last year it launched what it deems the world’s thinnest cosmetic dental veneer, UltraThineer™. This April, BMF secured FDA 510(k) clearance on the material.
“As we think about the future for BMF Biotechnology, we anticipate expanding our product portfolio to address a wider range of therapeutic areas and applications, revolutionizing the way drugs are developed and tested,” Sun added. “Our goal is to be a globally recognized leader in organ-on-a-chip technology, driving transformative advancements in drug discovery, cosmetic development, toxicity testing, and personalized medicine to improve human health and safety.”
Boston Micro Fabrication
FOUNDED: 2016 in Boston, San Diego Research Institute in 2022
CEO: John Kawola
LOCAL DIVISION HQ: San Diego
EMPLOYEES: 10 in San Diego; 200+ globally
BUSINESS: biotech
CAPITAL RAISED: $80 million
WEBSITE: bmf3d.com
CONTACT: info@bmf3d.com
NOTABLE: BMF was named one of the Boston Business Journal’s “Fast 50” companies, an annual honor recognizing the 50 fastest-growing private companies in Massachusetts.
San Diego, CA
Marine missing after training activity off San Diego is declared dead
The U.S. military identified a Minnesota Marine stationed in Southern California who went missing off San Diego last week, and confirmed his death.
Lance Cpl. Armando Ortiz Canseco was declared deceased Saturday. It is believed he was lost at sea after a training exercise.
“On behalf of the Marines and sailors of the 13th Marine Expeditionary Unit, I extend our deepest condolences to the family and loved ones of Lance Cpl. Ortiz Canseco,” Col. Richard Alvarez, the commanding officer of the 13th Marine Expeditionary Unit, said in a statement.
Ortiz Canseco was reported missing from the amphibious transport dock ship USS Anchorage early Thursday morning. His disappearance resulted in an extensive search and rescue operation, with efforts beginning around 1:20 a.m. Thursday.
The search spanned roughly 2,400 square miles and involved officials from the Navy, Marine Corps, Coast Guard and Air Force who used three surface ships and 12 aircraft, according to the military.
The Marine went missing during a training operation involving the 13th Marine Expeditionary Unit and the Makin Island Amphibious Ready Group.
After nearly two full days of searching, the Navy transitioned to recovery operations.
“He earned the title of United States Marine and served his country with honor and commitment,” Alvarez said. “We mourn alongside his family, and we remain committed to bringing him home.”
This incident marks the second time in recent weeks that the U.S. military has searched for missing service members.
The remains of two Army soldiers who went missing while off duty from military exercises in Morocco were recovered in May, according to the Army.
Officials did not initially identify Ortiz Canseco on Thursday or disclose the circumstances surrounding his disappearance, saying his family needed to be notified first.
His death continues to be under investigation.
Ortiz Canseco enlisted in the Marine Corps in April 2023 and reported for training at Marine Corps Recruit Depot San Diego.
His individual awards include the Marine Corps Good Conduct Medal and Sea Service Deployment Ribbon.
Times staff writer Alene Tchekmedyian contributed to this report.
San Diego, CA
Adobe Falls: The elusive waterfall that briefly returns after San Diego rains
Blink, and you might miss it.
Adobe Falls isn’t Niagara Falls — or anything close — but after winter rains, a seasonal waterfall briefly appears in a narrow Del Cerro canyon, hidden beneath streets, homes, and San Diego State University property.
The waterfall forms along Alvarado Creek, which drains parts of eastern San Diego, including the SDSU area and surrounding neighborhoods. In wet months, runoff moves through a steep canyon and drops over a short rock ledge known locally as Adobe Falls. In dry periods, the flow often fades to a trickle or disappears entirely, leaving exposed sandstone and a shaded canyon bed.
What makes the site stand out is its setting. Above the canyon are Del Cerro residential streets and university property tied to San Diego State. Below it, Alvarado Creek continues west as part of the Mission Valley watershed, eventually feeding into the San Diego River system. Like many urban drainages in San Diego, its flow is shaped by stormwater runoff, paved surfaces, and altered drainage patterns tied to development.

Access is restricted. The canyon sits on a mix of SDSU and city-managed land and has long been closed to the public due to safety concerns, including steep terrain, erosion, and unstable footing after rain. Although widely referenced in maps and online posts, it is not an official trail or recreation site.
The canyon itself pre-dates modern development in Del Cerro. It is part of a broader network of inland waterways and canyon corridors used for thousands of years by the Kumeyaay, whose presence shaped movement and settlement patterns across the region.
In the mid-20th century, as Del Cerro developed, homes and roads were built along canyon rims rather than through them, leaving Alvarado Creek intact as a drainage system. Adobe Falls remained within that corridor even as surrounding hillsides filled with residential and institutional development.
Today, Adobe Falls remains a small but persistent reminder that San Diego’s natural drainage systems still function within a heavily built environment — appearing briefly after storms, then receding back into the canyon until the next rain.
Read more history stories here, and do you have a story to tell? Send an email to DebbieSklar@cox.net.
Sources:
City of San Diego – Stormwater & Watershed Division (Alvarado Creek / Mission Valley watershed)
San Diego State University – planning and environmental impact documentation for adjacent canyon areas
U.S. Geological Survey (USGS) – San Diego County watershed and hydrology mapping (Alvarado Creek / San Diego River system context)
San Diego History Center – Kumeyaay regional land use and inland canyon corridor history
City of San Diego Planning Department – land use records and access restrictions for Adobe Falls area
California State Historic Landmark files – Adobe Falls (Landmark No. 80)
San Diego, CA
Former City Manager, Jack McGrory: Straight Talk About San Diego, Part 2
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