Science
News Analysis: It’s harder to justify COVID vaccine for children if pandemic’s end is near
If this had been December 2020, or August 2021, the argument for vaccinating younger kids towards COVID-19 could be straightforward to make.
With case counts surging and hospitals close to capability, giving younger youngsters a jab could be counted on to gradual transmission of a virus that’s killing 1000’s of Individuals a day. The chance that inoculation might trigger coronary heart irritation in younger youngsters seems to be minuscule. Countering the coronavirus would clearly win out.
Nevertheless it’s late October 2021, and the virus seems to be in retreat. New infections and deaths have each plunged greater than 45% since a surge in September. And after a number of waves of infections, greater than 1 in 4 U.S. residents have probably battled the coronavirus and gained some immunity in consequence.
All that’s excellent news, however it additionally signifies that widespread vaccination of the nation’s grade-school inhabitants presents much less of an upside than it could have earlier than.
That makes it tougher to say there’s sufficient to be gained by the shot to offset the theoretical chance of coronary heart dangers — a draw back that’s not but been measured.
These are the calculations specialists are attempting to make as they resolve whether or not Pfizer and BioNTech’s COVID-19 vaccine for teenagers ages 5 to 11 must be made out there — and particularly whether or not it must be advisable — for all 28 million U.S. kids on this age group.
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On Tuesday, the Meals and Drug Administration’s panel of scientific advisors voted overwhelmingly to suggest that entry to the vaccine be prolonged to households who need it for his or her younger kids.
However the panel additionally made clear it didn’t endorse the objective of vaccinating younger kids as shortly as potential. At this stage of the pandemic, there are simply too many unknowns to help blanket vaccinations for all, a number of panel members stated.
One uncertainty is whether or not pre-pubescent boys face the identical threat of coronary heart irritation in response to the vaccine that has been seen in teen boys and younger males.
One other is whether or not the Facilities for Illness Management and Prevention are appropriate in estimating that no less than 40% of elementary-school-aged kids have already been contaminated and at the moment are protected to some extent.
However essentially the most intriguing uncertainty is state of the pandemic. Whether or not we’re close to the tip of the outbreak or simply resting between waves is an unknown with sweeping implications, the FDA advisors stated.
“If traits proceed the way in which they’re going, this will not be the emergency it’s now,” immunologist Dr. James E.Okay. Hildreth stated at Tuesday’s assembly.
The reservations expressed by Hildreth and others got here after an FDA workers evaluation confirmed that underneath some assumptions a couple of waning pandemic, vaccinating all kids ages 5 to 11 couldn’t be justified.
For the report:
3:02 p.m. Oct. 29, 2021An earlier model of this story incorrectly stated the dangers of vaccine-induced myocarditis would exceed the advantages of vaccination in younger kids if the variety of hospitalizations exceeded 11,500 per day.
In a state of affairs during which new hospitalizations dropped to 1,150 per day and new infections to 7,000, charges of hospitalization as a result of vaccine-induced myocarditis might exceed these prevented by the vaccine.
We’re not there but. But when present traits proceed, we may very well be quickly.
Even whether it is burning itself out, the pandemic continues to afflict Black and brown households disproportionately, stated Hildreth, president of Meharry Medical Faculty in Nashville. That’s motive sufficient to induce that folks get entry to a COVID-19 vaccine for his or her younger kids if they need it, he stated.
Dr. Michael Nelson, a College of Virginia immunologist who additionally serves on the FDA’s advisory panel, agreed that “offering a option to a completely knowledgeable public is a reasonably good path ahead.”
He burdened that the panel’s help for authorizing the vaccine “shouldn’t be a mandate” to inoculate all youngsters between ages 5 and 11.
Reflecting the blinking-yellow indicators of his fellow panel members, College of Michigan epidemiologist Dr. Arnold Monto acknowledged he had “reservations” over “how teams now we have no management over will act” if the pediatric COVID-19 vaccine is allowed for emergency use.
Key amongst these teams are politicians and public well being officers, who’ve hinted at vaccine mandates for younger kids as soon as the FDA makes the pictures out there.
President Biden has inspired governors, healthcare organizations and enterprise homeowners to require COVID-19 vaccinations for adults as a situation of coming to work, attending public occasions, and consuming and consuming in bars and eating places.
The ensuing mandates have induced a livid backlash throughout the nation. Montana has barred vaccine mandates of any sort, and governors or legislatures in Texas, Georgia and several other different states have acted to severely restrict enforcement of mandates carried out by native authorities or personal entities.
Adopting vaccine mandates for schoolchildren could be a bit extra sophisticated. Whereas the full-strength Pfizer-BioNTech vaccine has obtained the FDA’s unqualified blessing for these over 16, the company received’t grant greater than emergency authorization to be used in younger youngsters anytime quickly. Till it does, COVID vaccine mandates for faculties may very well be on shaky authorized floor.
However these racing to immunize schoolchildren must be able to acknowledge that youthful youngsters are at decrease threat of extreme COVID sickness than are adults, stated Dr. Monica Gandhi, an infectious illness skilled at UC San Francisco.
“The vote got here in, and it was like, ‘Yay, we’ll be on fairgrounds vaccinating all the children subsequent week,’” she stated.
In impact, whereas adults crowd into sports activities arenas, bars and eating places to eat, drink and cheer unmasked, they’re pushing for kids get the vaccine earlier than all the security issues have been resolved.
“We’re sort of asking kids to take one for the group,” Gandhi stated.
Dr. Rochelle Walensky, director of the CDC, pushed again towards the suggestion that the necessity to get kids vaccinated had handed.
“There’s urgency as a result of we’re seeing illness in kids, we’ve seen deaths in kids, we’ve seen ‘lengthy COVID,’” Walensky stated Wednesday at a White Home briefing, referring to a lingering type of the illness. “Definitely we’ve seen instances come down earlier than, and the way in which to forestall surges once more is to get increasingly more folks vaccinated.”
CDC knowledge introduced on the FDA advisory committee assembly confirmed that COVID-19 now ranks eighth on the record of main causes of dying for kids ages 5 to 11. Over the course of the pandemic, the illness has claimed the lives of no less than 94 kids on this age group.
And whereas hospitalizations amongst these younger kids have dipped within the final two weeks, they continue to be roughly as excessive as they had been within the pandemic’s darkest days final winter.
The typical each day dying toll for Individuals of all ages nonetheless tops 1,000, and a season of colder, drier climate could revive flagging transmission charges, Walensky famous.
“We should stay vigilant,” she stated.
Science
Cluster of farmworkers diagnosed with rare animal-borne disease in Ventura County
A cluster of workers at Ventura County berry farms have been diagnosed with a rare disease often transmitted through sick animals’ urine, according to a public health advisory distributed to local doctors by county health officials Tuesday.
The bacterial infection, leptospirosis, has resulted in severe symptoms for some workers, including meningitis, an inflammation of the brain lining and spinal cord. Symptoms for mild cases included headaches and fevers.
The disease, which can be fatal, rarely spreads from human to human, according to the U.S. Centers for Disease Control and Prevention.
Ventura County Public Health has not given an official case count but said it had not identified any cases outside of the agriculture sector. The county’s agriculture commissioner was aware of 18 cases, the Ventura County Star reported.
The health department said it was first contacted by a local physician in October, who reported an unusual trend in symptoms among hospital patients.
After launching an investigation, the department identified leptospirosis as a probable cause of the illness and found most patients worked on caneberry farms that utilize hoop houses — greenhouse structures to shelter the crops.
As the investigation to identify any additional cases and the exact sources of exposure continues, Ventura County Public Health has asked healthcare providers to consider a leptospirosis diagnosis for sick agricultural workers, particularly berry harvesters.
Rodents are a common source and transmitter of disease, though other mammals — including livestock, cats and dogs — can transmit it as well.
The disease is spread through bodily fluids, such as urine, and is often contracted through cuts and abrasions that contact contaminated water and soil, where the bacteria can survive for months.
Humans can also contract the illness through contaminated food; however, the county health agency has found no known health risks to the general public, including through the contact or consumption of caneberries such as raspberries and blackberries.
Symptom onset typically occurs between two and 30 days after exposure, and symptoms can last for months if untreated, according to the CDC.
The illness often begins with mild symptoms, with fevers, chills, vomiting and headaches. Some cases can then enter a second, more severe phase that can result in kidney or liver failure.
Ventura County Public Health recommends agriculture and berry harvesters regularly rinse any cuts with soap and water and cover them with bandages. They also recommend wearing waterproof clothing and protection while working outdoors, including gloves and long-sleeve shirts and pants.
While there is no evidence of spread to the larger community, according to the department, residents should wash hands frequently and work to control rodents around their property if possible.
Pet owners can consult a veterinarian about leptospirosis vaccinations and should keep pets away from ponds, lakes and other natural bodies of water.
Science
Political stress: Can you stay engaged without sacrificing your mental health?
It’s been two weeks since Donald Trump won the presidential election, but Stacey Lamirand’s brain hasn’t stopped churning.
“I still think about the election all the time,” said the 60-year-old Bay Area resident, who wanted a Kamala Harris victory so badly that she flew to Pennsylvania and knocked on voters’ doors in the final days of the campaign. “I honestly don’t know what to do about that.”
Neither do the psychologists and political scientists who have been tracking the country’s slide toward toxic levels of partisanship.
Fully 69% of U.S. adults found the presidential election a significant source of stress in their lives, the American Psychological Assn. said in its latest Stress in America report.
The distress was present across the political spectrum, with 80% of Republicans, 79% of Democrats and 73% of independents surveyed saying they were stressed about the country’s future.
That’s unhealthy for the body politic — and for voters themselves. Stress can cause muscle tension, headaches, sleep problems and loss of appetite. Chronic stress can inflict more serious damage to the immune system and make people more vulnerable to heart attacks, strokes, diabetes, infertility, clinical anxiety, depression and other ailments.
In most circumstances, the sound medical advice is to disengage from the source of stress, therapists said. But when stress is coming from politics, that prescription pits the health of the individual against the health of the nation.
“I’m worried about people totally withdrawing from politics because it’s unpleasant,” said Aaron Weinschenk, a political scientist at the University of Wisconsin–Green Bay who studies political behavior and elections. “We don’t want them to do that. But we also don’t want them to feel sick.”
Modern life is full of stressors of all kinds: paying bills, pleasing difficult bosses, getting along with frenemies, caring for children or aging parents (or both).
The stress that stems from politics isn’t fundamentally different from other kinds of stress. What’s unique about it is the way it encompasses and enhances other sources of stress, said Brett Ford, a social psychologist at the University of Toronto who studies the link between emotions and political engagement.
For instance, she said, elections have the potential to make everyday stressors like money and health concerns more difficult to manage as candidates debate policies that could raise the price of gas or cut off access to certain kinds of medical care.
Layered on top of that is the fact that political disagreements have morphed into moral conflicts that are perceived as pitting good against evil.
“When someone comes into power who is not on the same page as you morally, that can hit very deeply,” Ford said.
Partisanship and polarization have raised the stakes as well. Voters who feel a strong connection to a political party become more invested in its success. That can make a loss at the ballot box feel like a personal defeat, she said.
There’s also the fact that we have limited control over the outcome of an election. A patient with heart disease can improve their prognosis by taking medicine, changing their diet, getting more exercise or quitting smoking. But a person with political stress is largely at the mercy of others.
“Politics is many forms of stress all rolled into one,” Ford said.
Weinschenk observed this firsthand the day after the election.
“I could feel it when I went into my classroom,” said the professor, whose research has found that people with political anxiety aren’t necessarily anxious in general. “I have a student who’s transgender and a couple of students who are gay. Their emotional state was so closed down.”
That’s almost to be expected in a place like Wisconsin, whose swing-state status caused residents to be bombarded with political messages. The more campaign ads a person is exposed to, the greater the risk of being diagnosed with anxiety, depression or another psychological ailment, according to a 2022 study in the journal PLOS One.
Political messages seem designed to keep voters “emotionally on edge,” said Vaile Wright, a licensed psychologist in Villa Park, Ill., and a member of the APA’s Stress in America team.
“It encourages emotion to drive our decision-making behavior, as opposed to logic,” Wright said. “When we’re really emotionally stimulated, it makes it so much more challenging to have civil conversation. For politicians, I think that’s powerful, because emotions can be very easily manipulated.”
Making voters feel anxious is a tried-and-true way to grab their attention, said Christopher Ojeda, a political scientist at UC Merced who studies mental health and politics.
“Feelings of anxiety can be mobilizing, definitely,” he said. “That’s why politicians make fear appeals — they want people to get engaged.”
On the other hand, “feelings of depression are demobilizing and take you out of the political system,” said Ojeda, author of “The Sad Citizen: How Politics is Depressing and Why it Matters.”
“What [these feelings] can tell you is, ‘Things aren’t going the way I want them to. Maybe I need to step back,’” he said.
Genessa Krasnow has been seeing a lot of that since the election.
The Seattle entrepreneur, who also campaigned for Harris, said it grates on her to see people laughing in restaurants “as if nothing had happened.” At a recent book club meeting, her fellow group members were willing to let her vent about politics for five minutes, but they weren’t interested in discussing ways they could counteract the incoming president.
“They’re in a state of disengagement,” said Krasnow, who is 56. She, meanwhile, is looking for new ways to reach young voters.
“I am exhausted. I am so sad,” she said. “But I don’t believe that disengaging is the answer.”
That’s the fundamental trade-off, Ojeda said, and there’s no one-size-fits-all solution.
“Everyone has to make a decision about how much engagement they can tolerate without undermining their psychological well-being,” he said.
Lamirand took steps to protect her mental health by cutting social media ties with people whose values aren’t aligned with hers. But she will remain politically active and expects to volunteer for phone-banking duty soon.
“Doing something is the only thing that allows me to feel better,” Lamirand said. “It allows me to feel some level of control.”
Ideally, Ford said, people would not have to choose between being politically active and preserving their mental health. She is investigating ways to help people feel hopeful, inspired and compassionate about political challenges, since these emotions can motivate action without triggering stress and anxiety.
“We want to counteract this pattern where the more involved you are, the worse you are,” Ford said.
The benefits would be felt across the political spectrum. In the APA survey, similar shares of Democrats, Republicans and independents agreed with statements like, “It causes me stress that politicians aren’t talking about the things that are most important to me,” and, “The political climate has caused strain between my family members and me.”
“Both sides are very invested in this country, and that is a good thing,” Wright said. “Antipathy and hopelessness really doesn’t serve us in the long run.”
Science
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