Health
Ukraine war: Kyiv transforms surgical hospital into battleground medical facility
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Russia’s bloody invasion of Ukraine has pressured the workers to rework Kyiv’s largest hospital, Medical Hospital #8, right into a battleground medical facility, in accordance with a current Wall Road Journal report.
Dermatologists and cardiologists now help with triaging wounded sufferers arriving from artillery and rocket barrages because the hospital sits inside 10 miles of the battleground, the paper famous.
The workers are numb to the air raid sirens as a result of they’re so frequent to take significantly anymore, and don’t put on face masks due to the fixed background noise of combating as they attempt to discuss to speak, per the Journal.
“In fact we’re not what we was, however neither is the remainder of the nation,” stated Dr. Igor Khomenko, the hospital director.
He labored for 30 years as a army surgeon, however give up earlier this 12 months to turn into a civilian, but his hope for a quiet civilian life was dashed when two weeks after he give up the army, the Russian invasion started, per the Journal.
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“I attempted civilian life and it didn’t final lengthy,” he famous, who now sleeps on a sofa in his workplace away from his spouse who has taken refuge far-off from the battlefield.
He lowered his hospital workers by half and canceled elective surgical procedures, so 200 hospital beds can be free for sufferers wounded by the conflict, the paper stated.
The hospital instances are a window into conflict ways as they evolve – initially they have been primarily gunshot wounds as gun battles rage, however because the conflict has progressed, extra sufferers are arriving with shrapnel wounds and concussions, as each side undergo from blast explosions from a distance, in accordance with the information report.
However regardless that the hospital’s location is so near the combating, Khomenko notes it has one benefit – the wounded can go immediately from the battlefield to the working room.
This bypasses the standard manner the wounded are handled in conflict, the place often they first get handled on the battlefield as combating continues, then cell area hospitals whereas they await their alternative to be transported to a surgical hospital for definitive care.
Khomenko describes one case: After a person was shot by means of the guts, the hospital workers saved his life by cracking his chest open and stitching the outlet shut earlier than the affected person may bleed to demise.
He advised the paper he operated on the person and plugged the outlet in his coronary heart along with his personal index finger whereas it continued to pump to ensure the person didn’t bleed out.
Just lately the Journal reported one other instance of Ukrainians struggling because of the unprovoked invasion. After the glass home windows of the hospital shook from a big thud from a Russian missile, aged civilians with bloody faces quickly wobbled to the hospital entrance, with bandages on their heads.
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After nurses helped the sufferers launch their padded jackets as items of glass hidden in folds of their clothes pierced the ground, they wheeled them to the working room on metal gurneys, the place medical doctors painstakingly used tweezers to take away the shards of glass out of 1 man’s face, arms and buttocks, all whereas the affected person lay on his abdomen, clenching his fist in agony.
But it surely wasn’t over. The injuries then needed to be stitched up, the paper famous.
“They inform me to return again to Gaza, that Ukraine is simply too harmful,” stated Dr. Makhmud Akmad, the hospital’s main vascular surgeon who was born in Gaza, however got here to Ukraine to review drugs and stayed after assembly a fellow pupil who he later married.
“I inform them that I’ll keep right here, Ukraine is my dwelling now.”
Health
Aging slowdown could be surprise benefit of existing medication, research shows
A drug used to prevent organ rejection in kidney transplant patients is being touted for potentially slowing down aging.
The immune-suppressing medication rapamycin, also known as sirolimus, is being used off-label as a means of extending longevity.
“By targeting a key pathway (mTOR) in cells, this drug has been shown to extend lifespan in animals and could be beneficial to prevent age-related diseases in humans,” Dr. Andrea B. Maier — a professor in healthy aging and dementia research at the Director of the Centre for Healthy Longevity at the National University of Singapore — told Fox News Digital.
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Maier was co-author of a recent review study that explored how rapamycin affected healthy humans.
The review, which was published in the journal Lancet Healthy Longevity, found that the medication improved the effects of aging on the skin.
“Rapamycin and its derivatives improve the immune and cardiovascular function of healthy individuals or individuals with aging-related diseases,” Maier said in an email.
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Daniel Tawfik, a molecular biologist and co-founder of Healthspan, a digital medical clinic that focuses on anti-aging and longevity-promoting therapies, said his team uses rapamycin to help slow down the rate of aging.
“We view this through the lens of reducing the accumulation of damaged senescent cells,” Tawfik, who is based in Santa Monica, California, told Fox News Digital.
Senescent cells are cells that no longer function properly, but linger in the body and can contribute to tissue deterioration and inflammation, the expert said.
“By lowering the rate at which healthy cells transform into senescent cells, rapamycin can slow the aging process at the tissue level, helping to preserve organ function and overall health as we age,” he added.
Off-label use
In the U.S., rapamycin is approved by the Food and Drug Administration (FDA) for its immune-suppressing properties in patients with kidney transplants and certain cancers.
It is not approved for use as an age-defying drug.
“Sirolimus (rapamycin) has not been evaluated by the FDA for safety and effectiveness as an anti-aging treatment,” a press officer for the FDA confirmed to Fox News Digital.
“Rapamycin can slow the aging process at the tissue level, helping to preserve organ function and overall health.”
Despite this, rapamycin is being used “off-label” for anti-aging purposes, according to Elaena Quattrocchi, a registered pharmacist and an associate professor at Long Island University College of Pharmacy in Brooklyn, New York.
“Off-label means the FDA has not approved the drug for this use,” she told Fox News Digital.
When prescribing a drug for off-label use, the provider must explain to the patient that the medication has not been approved for the indication for which they are prescribing it, Quattrocchi noted.
“People taking this medication must discuss with their primary care provider and pharmacist about the potential side effects and drug interactions,” she said.
Benefits of rapamycin
Tawfik’s company currently treats more than 3,500 patients with rapamycin, he told Fox News Digital.
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His team has seen numerous benefits of its off-label anti-aging use, he said, including improved cellular health, reduced risk of age-related diseases and the potential for enhanced longevity.
“Under proper medical supervision, many of our patients experience a marked reduction in inflammation and improvement in conditions related to autoimmunity,” Tawfik said.
“For example, patients with osteoarthritis often report significant relief from joint pain after starting rapamycin.”
The expert also noted that certain biomarkers linked to healthspan and longevity — such as reduced inflammation markers and enhanced metabolic health — were seen in the bloodwork of the patients using rapamycin.
Screening and safety
Patients need a prescription for rapamycin, experts told Fox News Digital.
Individuals are screened to determine whether they are candidates for the treatment. If it is prescribed, patients are monitored carefully when taking the drug.
“It is essential that rapamycin use is overseen by a physician.”
“It is essential that rapamycin use is overseen by a physician to ensure that dosing is effective yet safe, as high doses can lead to unwanted immunosuppression,” Tawfik warned.
Maier echoed that rapamycin and its derivatives are not for self-medication use.
“An important step is to first measure the patient’s biological age and investigate why the pace of aging might be faster,” she told Fox News Digital.
“Then a tailored approach to match the measures with interventions at need is required.”
Quattrocchi and Tawfik both emphasized the importance of working with an accredited pharmacy that sources the drug directly from a reputable manufacturer.
Rapamycin is not recommended for immunocompromised individuals or those taking immunosuppressant medication, Tawfik cautioned.
It is not typically used in younger adults, he added, since starting this regimen at such an early age is unnecessary.
Calls for more research
There are limited studies on the effects of rapamycin on humans and organ systems, Maier noted.
In researching studies of the drug, Maier’s research team found that adverse reactions in healthy individuals were classified “as mild or moderate and were reversible after the discontinuation of treatment.”
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However, the study authors stated, “there were increased numbers of infections and increases in total cholesterol, LDL cholesterol and triglycerides in individuals with aging-related diseases.”
“Future studies should assess the remaining unexamined systems and test the effects of long-term exposure to rapamycin and its derivatives.”
The majority of studies exploring rapamycin’s effects on aging have been conducted on mice and other animals as well as experimental models, researchers told Fox News Digital.
“The reason scientists are so interested in rapamycin is that in every species that’s been studied to date – yeast, worms, flies, mice – when they are given rapamycin, healthspan and lifespan are extended,” Tawfik noted.
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“No other intervention has that degree of validation.”
Quattrocchi agreed that further research is needed into the drug’s proper dosing, adverse effects, and potential anti-aging benefits in healthy individuals and those with medical conditions.
Health
Lack of sleep during pregnancy could impact baby's development, study reveals
Sleep is crucial, especially for pregnant women.
Inadequate sleep during pregnancy can have many negative effects, including neurodevelopmental delays for the child, according to a new study.
The research, which was published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism, examined the effects of short sleep duration (SSD) — defined as sleeping fewer than seven hours per night — on pregnant women.
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The China-based researchers analyzed sleep data from 7,059 mother-child pairs from three Chinese hospitals. The children were screened for developmental delays from 6 months to 3 years old.
Insufficient sleep during pregnancy was associated with an increased risk of delays in nervous system development, the researchers found.
“Our findings highlight the importance of addressing sleep quality during pregnancy to potentially mitigate the risk of long-term cognitive and behavioral issues in children,” lead study author Peng Zhu, M.D., of Anhui Medical University and the MOE Key Laboratory of Population Health Across Life Cycle in Hefei, China, told Fox News Digital.
“Additionally, we discovered that cord blood C-peptide levels partially mediate this association, indicating that maternal sleep might impact fetal glucose metabolism and, consequently, the child’s neurodevelopment.”
LACK OF SLEEP POSES CONCERNING RISK FOR KIDS, STUDY FINDS
The neurodevelopmental delays can lead to slower development of social, emotional, behavioral, motor, cognitive or speech skills, the new study revealed.
Boys, compared to girls, have a higher risk of these issues when their mothers experience SSD, the researchers found.
“This suggests that male fetuses might be more sensitive to the metabolic environment influenced by maternal sleep patterns,” Zhu said.
“This insight could lead to tailored interventions and a deeper understanding of how prenatal factors affect neurodevelopmental outcomes in a sex-specific manner.”
TO IMPROVE YOUR SLEEP, DO THIS ACTIVITY BEFORE BED, EXPERTS SUGGEST
Pregnant women may have trouble sleeping due to hormonal changes, discomfort, frequent urination and other factors, the Endocrine Society noted in a press release.
Dr. Jillian LoPiano, a Miami-based OB-GYN and chief health officer at the reproductive telehealth platform Wisp, acknowledged that the study measured a “possible biological marker” in neurological development.
“Much more research is needed to assess this relationship, but adequate sleep is known to be associated with proper growth and socioemotional development,” she told Fox News Digital.
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Poor sleep during pregnancy is also associated with other complications, including preeclampsia and gestational diabetes, LoPiano detailed.
“Adequate sleep is known to be associated with proper growth and socioemotional development.”
The expert recommended that pregnant women who are experiencing trouble sleeping consult with a doctor.
She also shared a few simple methods that can help improve sleep, including sleeping in a cool, dark room, minimizing screen time and distractions before bed, having adequate wind-down time, meditating and using support pillows.
The study researchers reiterated the importance of sleep hygiene.
“Pregnant women should be advised on strategies to improve sleep hygiene, such as maintaining a consistent sleep schedule, creating a relaxing bedtime environment, and avoiding caffeine and electronic devices before bed,” Zhu told Fox News Digital.
BEST AND WORST BEDTIMES FOR VARIOUS GENERATIONS
The researchers also recommend that health care providers screen pregnant women for sleep quality and provide guidance on achieving sufficient sleep.
“Furthermore, monitoring and managing gestational diabetes, which is linked to sleep patterns, should be emphasized,” Zhu added.
The study did have some potential limitations, the researchers acknowledged.
“As an observational study, we can only establish associations rather than causality,” Zhu told Fox News Digital.
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“Additionally, sleep duration was self-reported, which may introduce some level of bias.”
Future studies with objective sleep measurements and larger sample sizes could help to validate the findings, the researcher added.
Health
Best friends have babies on the same day, at the same hospital: ‘Can’t make this stuff up’
Two best friends in Florida got to experience one of life’s most meaningful experiences together — becoming mothers — and it was caught on camera.
It started in May 2024, when Carolynn Shada announced her pregnancy to her best friend, Kali Gaynor — only to get a surprise of her own when her friend said she was also expecting.
“Our due dates were eight days apart, so we always joked around with the idea that we all could be at the hospital at the same time,” she wrote on Instagram.
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“NEVER did we ever think our BOYS would be born on the same day.”
Yet that’s exactly what happened — in August, the best friends went into labor and delivered their baby boys on the same day, in the same hospital.
“Her precious baby boy was born a bit after 12AM on Tuesday,” Shada wrote of her friend.
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“The hospital we were at was at a max capacity, so a few hours after she birthed her baby they moved her to triage. As morning rolls around, I head to the hospital and was placed in the EXACT room she delivered her baby in. My son was born later that afternoon with the same midwife group.”
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“You can’t make this stuff up!”
Fox News Digital reached out to Shada and Gaynor for comment.
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