Health
Depression risk spikes for those who eat these unhealthy foods, study finds: ‘Not a coincidence’
That bag of chips or slice of frozen pizza might make you happy while you’re eating it — but it could make you more susceptible to sadness long after the last bite.
A new study published in the journal JAMA Open Network found that eating “ultraprocessed” foods can contribute to a higher risk of depression.
Researchers from Brigham and Women’s Hospital and the Harvard T.H. Chan School of Public Health analyzed the dietary choices and mental health of more than 31,000 women between 42 and 62 years of age, according to the journal article.
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The data came from the Nurses’ Health Study II, conducted between 2003 and 2017.
All participants filled out a food questionnaire every four years, disclosing whether they consumed ultraprocessed foods (UPFs) or not.
A new study published in the journal JAMA Open Network found that eating “ultraprocessed” foods can contribute to a higher risk of depression. (iStock)
UPFs were grouped into nine categories: ultraprocessed grain foods, sweet snacks, ready-to-eat meals, fats and sauces, ultraprocessed dairy products, savory snacks, processed meat, beverages and artificial sweeteners.
“Ultraprocessed foods are those that include many preservatives, stabilizers, bulking or gelling agents, as well as artificial colors and flavors,” said Tanya Freirich, a registered dietitian nutritionist in Charlotte, North Carolina, who practices as The Lupus Dietitian. (She was not involved in the study.)
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“They are generally the types of foods that are shelf-stable for years to come,” she went on.
“Ultra-processed foods include things like chips, candies, frozen ‘TV dinners,’ chicken nuggets, sodas, sugar-filled breakfast cereals and packaged soups (the ‘just-add-hot-water’ type).”
“Our brain is just as vulnerable, if not more vulnerable than, other parts of our body to the negative effects of non-nutritive food additives.”
To gauge the participants’ mental health status, the researchers used two definitions: one, a strict definition requiring self-reported, clinician-diagnosed depression and regular antidepressant use; and two, a broad definition requiring clinical diagnosis and/or antidepressant use, as the journal article stated.
UPFs were grouped into nine categories: ultraprocessed grain foods, sweet snacks, ready-to-eat meals, fats and sauces, ultraprocessed dairy products, savory snacks, processed meat, beverages and artificial sweeteners. (iStock)
The researchers adjusted for other factors that could influence depression risk — such as age, body mass index, physical activity, smoking status, sleep health, chronic pain, alcohol consumption, income and any existing medical conditions.
After analyzing the results, the researchers found that people who ate higher amounts of ultraprocessed foods — in particular, artificial sweeteners and artificially sweetened beverages — were more prone to depression.
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One possible reason is that artificial sweeteners cause chemical changes in the brain that can trigger the development of depression, they hypothesized.
“It is known that artificial sweeteners affect the brain through a different pathway than natural sweeteners like sugar or honey,” Frierich pointed out, noting that more research is needed in this area.
Those who had the highest intake of UPFs had a 34% to 49% increased risk of depression, the study found.
“Ultraprocessed foods include things like chips, candies, frozen ‘TV dinners,’ chicken nuggets, sodas, sugar-filled breakfast cereals and packaged soups.” (iStock)
Frierich said she was not surprised by the findings overall.
“Many studies have documented associations between some food additives and cancer, hormonal changes, weight gain and our mental health,” she told Fox News Digital.
“With that in mind, it is not surprising to me that there may be a link between ultraprocessed foods and depression.”
She also said, “Our brain is just as vulnerable, if not more vulnerable than, other parts of our body to the negative effects of non-nutritive food additives.”
The study’s limitations
While the study had a large sample size, high follow-up rate and advanced dietary assessment tools, it did have some limitations, the researchers pointed out.
The participants were primarily non-Hispanic White females.
Also, the study was observational — with no structured clinical interviews.
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“More diversity in the sample size may find differences among races and ethnicities in the association between UPF consumption and depression,” Frierich said.
“The high intake of UPFs was associated with greater BMI, high smoking rates, decreased likelihood of exercising regularly, as well as increased disease incidence of diabetes, HTN and dyslipidemia.”
Also, because this was an observational study and not a controlled one, it’s not a certainty that ultraprocessed foods were the determining factor in the depression, she noted.
“Depressed people may not have the energy to grocery shop, meal-prep their lunches or cook meals from scratch.” (iStock)
“A prospective study like this one only examines the association between the UPF and mental state,” Frierich said.
“Were people feeling more depressed and then turning to UPF as a form of comfort or convenience? Depressed people may not have the energy to grocery shop, meal-prep their lunches or cook meals from scratch.”
“Depressed people may not have the energy to grocery shop, meal-prep their lunches or cook meals from scratch.”
“While we cannot figure out what came first, the depression or the UPF, is it vital to note that when people reduced their intake of UPF, there was a consequential reduction in depression,” she added.
“The association is not a coincidence.”
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Lauren Harris-Pincus, a registered dietitian nutritionist who has been practicing for over 25 years in the New York/New Jersey area, told Fox News Digital that it’s important to take into account social determinants of health and access.
“Perhaps someone who eats most of their diet as UPF doesn’t have access to fresh foods in their neighborhood. Maybe they work several jobs and don’t have time to cook, or are caring for loved ones and sacrificing their own self-care,” said Harris-Pincus, who was not involved in the study.
Tips for improving diet for better mental health
When treating clients, Frierich recommends that they consider their diets as an important piece of the puzzle for mental health.
“Dietary changes do not need to be dramatic or expensive,” she said. “Start small by swapping out one processed snack for a piece of fruit, nuts, seeds or a raw vegetable. An apple, baby carrots or handful of nuts can be just as quick as a processed snack, but [this] reduces your intake of UPF by at least one serving.”
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With small changes like these throughout the week, she said people may notice improvements in energy, digestion and other areas.
As artificial sweeteners were noted to be associated with depression, Frierich suggests choosing honey, sugar or agave nectar instead.
For beverages, she recommends opting for lightly sweetened or unsweetened tea, coffee or seltzer water instead of diet sodas.
“Ultimately, we want to strive for a diet rich in fruits, veggies, nuts, beans, seeds, whole grains and lean proteins,” Harris-Pincus said. (iStock)
Frierich also suggests using maple syrup, fruit juice-based popsicles and 100% fruit juice in place of sugar-free options.
“Artificial sweeteners can cause another problem — as we perceive them to be hundreds to thousands of times sweeter-tasting than natural sugars. If you use them often, you may have become accustomed to this ultra-sweet flavor,” she warned.
“Making the switch to natural sugars may taste less sweet at first, but your taste buds can and will adjust over time.”
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All types of sugar should be consumed in moderation, the dietitian added.
The World Health Organization recommends limiting added sugars to 25 grams or less (six teaspoons) per day for adults.
Added Friedrich, “Decreasing your intake of both artificially and naturally sweetened beverages and foods is a great idea for your physical and mental health.”
For beverages, opt for lightly sweetened or unsweetened tea, coffee or seltzer water instead of diet sodas, advised one dietitian nutritionist. (iStock)
Another important consideration is that not all UPFs are the same, Harris-Pincus said.
“When we message about limiting ultraprocessed foods, there is nuance — they are not all created equal.”
Simply peeling a vegetable, for example, is a form of processing, she noted — and while soy milk might be classified as an ultraprocessed food in a database, it is essentially a nutrient-dense whole food.
“Ultimately, we want to strive for a diet rich in fruits, veggies, nuts, beans, seeds, whole grains and lean proteins,” Harris-Pincus said.
“When we message about limiting ultraprocessed foods, there is nuance — they are not all created equal.”
“Some ultraprocessed food is OK, especially if combining processed foods and fresh foods makes it easier to get family meals on the table.”
For more Health articles, visit www.foxnews.com/health.
Cases of the COVID-19 variant Omicron BA.2.86, also known as Pirola, have tripled in two weeks, comprising between 5% and 15% of all infections, according to the Centers for Disease Control and Prevention (CDC).
The COVID-19 variant Omicron BA.2.86 — as well as its offshoots, including JN.1 — has been reclassified as a “variant of interest” by the World Health Organization (WHO).
Despite its prevalence, BA.2.86 “does not appear to be driving increases in infections or hospitalizations in the United States,” the CDC stated in its report.
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Both the CDC and WHO agree that “the public health risk posed by this variant is low compared with other circulating variants.”
The updated COVID-19 vaccines that were approved by the FDA in September are believed to “increase protection against BA.2.86, as they do for other variants,” the CDC noted.
Cases of the COVID-19 variant Omicron BA.2.86, also known as Pirola, have tripled in two weeks, comprising between 5% and 15% of all infections, according to the CDC. (iStock)
“To date, existing vaccines have been very effective in protecting people, particularly those who have been boosted multiple times through a vaccine or natural infection, not only from symptomatic infection, but importantly from severe disease, hospitalization and death,” said Richard Reithinger, PhD, a distinguished research fellow in the Global Health Division at International Development Group in Washington, D.C., in a statement to Fox News Digital.
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The CDC said it is not clear whether BA.2.86 causes different symptoms — but noted that most variants produce similar effects.
“The types of symptoms and how severe they are usually depend more on a person’s immunity than which variant causes the infection,” the statement said.
Despite its prevalence, BA.2.86 (also known as Pirola) “does not appear to be driving increases in infections or hospitalizations in the United States,” the CDC stated in its report. (iStock)
The variant is also expected to respond to the current tests and treatments.
Reithinger noted that while the pandemic is officially over, COVID-19 is not a thing of the past.
“A concern of the new BA.2.86 variant was that because it has 35 mutations in the spike protein, it would be able to evade the immune response more readily than other variants that emerged in the last couple of months,” he told Fox News Digital.
“Early clinical data does not seem to indicate this being the case.”
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The increase in BA.2.86 cases is due to the U.S. entering the “COVID-19 season” and also a sufficient number of people having developed non-BA.2.86 immunity, according to the doctor.
Outside of vaccines, Reithinger recommends that high-risk groups adopt risk-mitigating behaviors, including wearing masks, frequently washing hands and avoiding crowded environments.
The updated COVID-19 vaccines that were approved by the FDA in September are believed to “increase protection against BA.2.86, as they do for other variants,” the CDC noted. (iStock)
“People — particularly those with greater risk of infection and severe disease — should continue to be sensitized and vigilant about COVID-19 and the disease it may cause,” he told Fox News Digital.
“People who are at greater risk of infection and severe disease should consult with their physicians about whether they should be administered one of the currently available boosters,” he added.
Those at highest risk include people older than 60 years, the immunocompromised, those with comorbidities such as asthma and diabetes, and people working in high-risk-of-exposure employment, such as the service industry, Reithinger noted.
For more Health articles, visit www.foxnews/health.
Health
Friends run for a cure for lupus, completing NYC Marathon in honor of longtime pal and lupus sufferer
All marathoners have their own particular motivations for running a 26.2-mile race — and for Molly Anderson, Sarah Edwards and Laura Haley, it was to honor Rosie De Queljoe Herzog, their longtime friend who is living with lupus.
As a 30th birthday surprise, the three runners flew De Queljoe Herzog from her home in Los Angeles to the Big Apple, where she was able to cheer them on as they ran the New York City Marathon on Nov. 5.
Anderson, Edwards and Haley were part of Team Life Without Lupus, the official competitive team of the Lupus Research Alliance, the largest private funder of lupus research in the world.
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The four friends shared with Fox News Digital what the experience meant to them — and how its impact is lasting well beyond that one day.
‘Something larger’
It was in 2021 when De Queljoe Herzog, a public relations professional, first started noticing symptoms, including rapid hair loss, joint pain, fatigue, swelling of her face and hands — and a malar rash (butterfly rash) on her face.
Pictured left to right: Molly Supple Anderson, Sarah Edwards, Rosie Herzog and Laura Haley at the NYC Marathon on Nov. 5, 2023. (Lupus Research Alliance)
“In the early days, I attributed the hair loss to a stressful 2020 and stressful work schedule, but it turned out to be something larger,” she told Fox News Digital.
In early 2022, De Queljoe Herzog was officially diagnosed with systemic lupus erythematosus, an inflammatory disease that occurs when the immune system attacks its own tissues.
She was hospitalized due to a lupus flare-up shortly after that.
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“I was put on a number of drugs to help quell the flare,” she said.
“I’ve been able to taper off some of the drugs since then, but am still on a few to help keep future flares at bay. I am no longer in a flare and am back to feeling healthy and ‘normal.’”
Over a decade of friendship
The four friends, all 30 years old, attended college together at the University of Arizona, where they competed on the triathlon team and developed an “inseparable bond,” said De Queljoe Herzog.
Their friendships continued to thrive after graduation. They were in each other’s weddings and took trips together.
Team Life Without Lupus, the official competitive team of the Lupus Research Alliance, are pictured with family and friends. “The energy and spectators, especially all our friends and family who came out to watch, were absolutely electric,” said Edwards. (Lupus Research Alliance)
“We’re all so uniquely different, but have such an incredible time when we’re all together,” De Queljoe Herzog told Fox News Digital.
She was “floored” when her friends said they would be running the NYC Marathon on her behalf to support the Lupus Research Alliance.
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“It was such a selfless act of friendship and love,” she told Fox News Digital. “They know how much lupus has impacted my overall health, and to see them rally around me and around lupus research was astonishing.”
De Queljoe Herzog and her husband traveled to New York City to watch the race.
“It was such a fun weekend and race day — we were able to catch them at three different points during the race to cheer them on,” she said. “It was an emotional day that I’ll remember for the rest of my life.”
“They know how much lupus has impacted my overall health, and to see them rally around me and around lupus research was astonishing.”
For those who are just starting their lupus journeys, De Queljoe Herzog stressed the importance of finding a support system to lean on.
“It can be a lonely road, but friends and family make it so much more manageable — especially friends who provide an endless supply of belly laughs.”
A race to remember
For the three runners, the race represented a way to support their friend while also marking a significant accomplishment.
“As much as I would do anything to take Rosie’s symptoms and flares away, I can’t,” said Anderson, who lives in Spain and works as a sports psychologist.
The team is pictured with Rosie De Queljoe Herzog along the race course. “Being able to run with two of my best friends for such a great purpose was incredibly gratifying and emotional,” said Anderson. (Lupus Research Alliance)
“It’s difficult living so far away, but after her diagnosis, I began to brainstorm ways to support her in my own way,” she went on. “That was when I had the idea to fund-raise for lupus research and encourage her to come to support the race.”
The other two runners, Edwards and Haley, were on board right away.
“We have always been motivated by physical and athletic challenges, so this seemed like the perfect combination of a challenge for us and raising money for an amazing cause,” said Edwards, who lives in Bend, Oregon, and works as an outreach coordinator for environmental organizations.
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“I’ve always dreamed of experiencing the magic of New York City and the energy I had always heard about in the marathon setting,” she went on.
Race day exceeded the team’s expectations, the women agreed.
“Being able to run with two of my best friends for such a great purpose was incredibly gratifying and emotional,” said Anderson.
The friends embrace along the NYC Marathon race course. Edwards described the race as “pure magic from start to finish.” (Lupus Research Alliance)
Edwards described the race as “pure magic from start to finish.”
“It was like running on cloud nine — it felt like a dream,” she said. “The energy and spectators, especially all our friends and family who came out to watch, were absolutely electric.”
She added, “My most sore muscles after the race were my cheeks from smiling the whole time.”
“Seeing Rosie at mile 18 made me remember why I was doing this, made me cry and helped me get to the finish line.”
Haley, who lives in Tucson, Arizona, and works as a physical therapist, said the best part of the race was taking the ferry to Staten Island and watching the sunrise over Manhattan with her best friends, as well as running through Brooklyn and the Bronx.
“The people were so fun and full of life, energy and support,” she said.
Haley said she struggled at around mile 16, and found herself wishing she had trained more.
The team is pictured celebrating along the marathon race course. “Every time I got tired or frustrated during training for this race, I would think of how much frustration Rosie has been through with lupus,” Edwards said. (Lupus Research Alliance)
“Oftentimes, while training or running the marathon, I would want to stop or ask myself, ‘Why am I doing this? This is miserable,’” she recalled.
“And those moments are when I would remember Rosie’s challenges. It would make me grateful for my healthy body and carry me through those rough times.”
Haley added, “Seeing Rosie at mile 18 made me remember why I was doing this, made me cry and helped me get to the finish line.”
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Running the marathon was “a huge joy” for all of them, said Edwards.
“And what has been even better is raising so much awareness among our family and friends through the fundraising process,” she said. “The more people know about lupus, the more support we can raise to find a cure one day.”
“Every time I got tired or frustrated during training for this race, I would think of how much frustration Rosie has been through with lupus.”
While De Queljoe Herzog is grateful for her friends’ support, they all agree that she is a huge source of motivation for them.
“Before her diagnosis, Rosie was always the most positive person I knew,” said Anderson. “She is an incredible listener and has an incredible ability to process information in a way that is productive. After her diagnosis, she was able to channel these parts of herself to listen to her body and manage her symptoms.”
Lupus is one of the most complex autoimmune diseases, according to the Lupus Research Alliance, which is based in New York City. “It affects each person differently with symptoms that are sometimes hard to detect and differ from patient to patient,” the organization notes on its website. (iStock)
Edwards said thoughts of her friend’s challenges helped get her through the race preparations.
“Every time I got tired or frustrated during training for this race, I would think of how much frustration Rosie has been through with lupus,” she told Fox News Digital.
“She is incredibly thoughtful and the kindest person I know. She motivates me to be a better person every day.”
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Albert Roy, president and CEO of Lupus Research Alliance, noted the significant impact that all of the teams make toward advancing research.
“We so appreciate how these young women and all the members of our Team Life Without Lupus ran the world’s largest marathon to raise both awareness and funds for lupus research,” he commented to Fox News Digital.
Women make up about 9 out of 10 adults with the disease.
“By pushing themselves to reach the finish line, they challenge us to keep striving to reach our goal — more treatments and ultimately a cure.”
Lupus is one of the most complex autoimmune diseases an individual can have, the organization notes. “It affects each person differently, with symptoms that are sometimes hard to detect and differ from patient to patient,” the group says on its website (lupusresearch.org).
While anyone can get lupus, the disease most often affects women, who make up about 9 out of 10 adults with the disease, the group also notes.
The chronic autoimmune disease affects millions of people worldwide. Doctors don’t know exactly what causes lupus, but they believe that something, or a combination of things, triggers the immune system to attack the body, WebMD indicates.
For more Health articles, visit www.foxnews/health.
People who get the flu vaccine may have improved heart health, according to a recent study published in Scientific Reports.
Researchers from the Shahid Beheshti University of Medical Sciences in Tehran, Iran, concluded that patients who received flu vaccinations had a 26% reduced risk of having a heart attack and were 33% less likely to die from cardiovascular disease.
This finding is based on a review of five randomized controlled trials that focused on myocardial disease and influenza vaccines.
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The patients who participated in the studies had all been diagnosed with cardiovascular disease previously and were 61 years old, on average.
Out of the total of 9,059 patients, 4,529 of them received the flu vaccine, while 4,530 received a placebo shot.
People who get the flu vaccine may have improved heart health, according to a recent study published in Scientific Reports. (iStock)
After a nine-month period, 621 of the people who received the placebo shot experienced “major cardiovascular events,” compared to 517 of the patients who received the flu vaccine.
Those outcomes included myocardial infarction, cardiovascular death and stroke.
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“Revealing a compelling insight into the potential benefits of influenza vaccination, our comprehensive meta-analysis, based on the latest randomized controlled trial data, demonstrates a significant interaction between influenza vaccination and the reduction of major cardiovascular events,” wrote the researchers of the study.
“Notably, patients who received the influenza vaccine experienced a remarkable risk reduction of over 20% in cardiovascular death.”
Patients who received flu vaccinations had a 26% reduced risk of having a heart attack and were 33% less likely to die from cardiovascular disease. (Joe Raedle/Getty Images)
As for why influenza vaccines seem to reduce the risk, the researchers noted that the shot could prevent inflammation and secondary infections, while also stabilizing plaque amounts in the heart.
The vaccine could also help stimulate the immune system, which the study authors noted is essential for cardiovascular health.
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Dr. Marc Siegel, clinical professor of medicine at NYU Langone Medical Center and a Fox News medical contributor, called the study “important” and said it “builds on what we already knew.”
He was not involved in the research.
Heart disease is the primary cause of death among U.S. adults, killing one person every 33 seconds, according to the CDC. (iStock)
“It is not surprising that flu shots would decrease the risk of heart attacks,” Siegel told Fox News Digital.
“The flu is one of the great enablers,” he went on. “It adds stress and inflammation to the body and decreases the overall immune response, all of which can lead to acute cardiac events.”
The flu “adds stress and inflammation to the body and decreases the overall immune response.”
The researchers called for further research to “elucidate the precise mechanisms driving this association and to explore the long-term impact of influenza vaccination on cardiovascular outcomes.”
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In the meantime, they recommended that “health care providers and policymakers should take heed of these findings and consider prioritizing influenza vaccination for patients with recent cardiovascular disease as a feasible and potentially life-saving preventive measure.”
Fox News Digital reached out to the study authors for additional comment.
Heart disease is the primary cause of death among U.S. adults, killing one person every 33 seconds, according to the Centers for Disease Control and Prevention (CDC).
For more Health articles, visit www.foxnews.com/health.
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