Health
Artificial intelligence detects cancer with 17% more accuracy than doctors in UCLA study
Artificial intelligence is outpacing doctors when it comes to detecting a common cancer in men.
A new study from UCLA found that an AI tool identified prostate cancer with 84% accuracy — compared to 67% accuracy for cases detected by physicians, according to a press release from the university.
Unfold AI, made by Avenda Health in California — a software recently cleared by the U.S. Food and Drug Administration — uses an AI algorithm to visualize the likelihood of cancer based on various types of clinical data.
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In the study, a team of seven urologists and three radiologists analyzed 50 cases where tumors had been removed, looking for signs of residual cancer.
A few months later, the AI software performed the same analysis.
A new study from UCLA found that an AI tool identified prostate cancer with 84% accuracy — compared to 67% accuracy for cases detected by physicians. (iStock)
The “negative margin rate” — a medical term that describes the absence of cancer cells surrounding the removed tissue — was 45 times greater in AI-detected cases, so the chances of cancer being left behind was far less.
Ali Kasraeian, M.D., a urologist at Kasraeian Urology in Jacksonville, Florida, said he uses the Unfold AI technology in his consultations with patients about managing their prostate cancer.
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“The AI takes the information that we currently have about a patient’s prostate cancer — like their pathology, imaging and biopsy results — and creates a 3D cancer estimation map,” he told Fox News Digital via email.
“The results we get from Unfold AI tell us if a patient will be better suited for focal therapy or more radical therapy, such as radical prostatectomy, or radiation therapy, ensuring we optimize their cancer cure, the personalization of their cancer care, and their quality of life goals.”
“AI is our new diagnostic ally — but like any tool, it works best in human hands.”
Based on these findings, the AI could lead to more accurate diagnoses and more targeted treatments, reducing the need for full-gland removal and the side effects that can come with it, such as incontinence and impotence, the researchers wrote.
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Joshua Trachenberg, PhD, is a professor of neurobiology at UCLA — and also a prostate cancer patient himself. After doctors found a slow-growing tumor on his prostate, they recommended removing the gland surgically — but he decided to explore other options.
“I got in touch with a team at UCLA, where I also am a faculty member, that was exploring alternate treatments to total gland removal,” Trachenberg, 56, told Fox News Digital via email.
The “negative margin rate” — a medical term that describes the absence of cancer cells surrounding the removed tissue — was 45 times greater in AI-detected cases, so the chances of cancer being left behind was far less. (iStock)
The UCLA researchers were testing an approach that uses ultrasound to heat tissue and is “focally guided” by MRI to destroy the cancerous tissue without damaging the rest of the gland, he said.
After some imaging scans, it was determined that Trachenberg was a candidate for the experimental therapy.
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“The 3D map created by Unfold AI enabled this team to identify precise margins, target the cancerous area and avoid any functional structures of the gland,” he said.
“It was able to visualize my cancer and it gave me a much better understanding of my case.”
“It was truly able to visualize my cancer and it gave me a much better understanding of my case.”
Trachenberg is now cancer-free and was able to avoid a radical prostatectomy.
“I would recommend to any prostate cancer patient who is told they need a radical prostatectomy that they take some time to look at all their options, [including] AI technologies,” said a doctor and patient (not pictured). (iStock)
“So many men are afraid of treatment because of the risks associated with gland removal, and Unfold AI enables therapies that don’t put men through the meat grinder,” he said.
This type of AI technology gives Trachenberg hope for the future of prostate cancer treatment, he told Fox News Digital.
“Too often, we are given only two options: Watch and wait for it to get worse, or take the entire gland out, which often leaves men with lifelong side effects that strain their physical health, emotional health and even their marriages,” he said.
“I would recommend to any prostate cancer patient who is told they need a radical prostatectomy that they take some time to look at all their options, [including] AI technologies.”
Potential risks, limitations
Dr. Harvey Castro, a board-certified emergency medicine physician and national speaker on artificial intelligence based in Dallas, Texas, was not involved in the new study but shared his insights on the potential risks associated with the technology.
Dr. Harvey Castro, a Dallas, Texas-based board-certified emergency medicine physician and national speaker on artificial intelligence, shared his insights on the potential risks associated with the technology. (Dr. Harvey Castro)
“The accuracy of AI depends heavily on the quality of the data it is trained on,” he told Fox News Digital. “Poor data can lead to inaccurate diagnoses.”
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Castro also cautioned against an “overreliance” on AI.
“While AI is a powerful tool, it should complement, not replace, the clinical judgment of health care professionals,” he said.
“AI is our new diagnostic ally,” Castro added. “But like any tool, it works best in human hands.”
“While AI is a powerful tool, it should complement, not replace, the clinical judgment of health care professionals,” an expert said. (iStock)
Privacy should also be considered when using this type of technology, according to Castro.
“Handling sensitive patient data with AI necessitates stringent data protection measures to maintain patient trust and confidentiality.”
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The cost of AI technologies can also be a significant barrier, added Kasraeian.
“I hope this study encourages us and future payers to make these innovations more accessible to urologists and, most importantly, to our patients.”
Health
Kids need snow days, not more screen time, doctors say amid winter storms
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Health
Men face hidden heart risk years earlier than women, study suggests
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Men are at a much higher risk of heart attacks than women earlier in life, a new study reveals.
Researchers at Northwestern University found that men start to develop coronary heart disease years earlier than women, with differences emerging as early as the mid-30s, according to a press release.
The study, published in the Journal of the American Heart Association (JAHA), analyzed data from more than 5,000 adults, aged 18 to 30, from the mid-1980s through 2020, as part of the Coronary Artery Risk Development in Young Adults (CARDIA) analysis.
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Men reached a 5% incidence of cardiovascular disease, including heart attack, stroke and heart failure, at around 50 years old compared to 57 for women.
Coronary heart disease, which is when blood vessels that supply the heart muscle become narrowed or blocked, was the main driver of the difference, as men reached a 2% incidence more than a decade before women. Stroke and heart failure emerged later in life.
Heart disease risk among men rises faster at around 35 years of age, research finds. (iStock)
Men’s risk began rising faster at around age 35 and remained high throughout midlife, according to the research. Everyone in the study was under 65 years old at the last follow-up.
Current guidelines generally recommend cardiovascular risk assessment beginning around age 40, which some experts say may miss an important window for early prevention.
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Heart disease develops over decades, with early markers detectable in young adulthood, according to senior study author Alexa Freedman, assistant professor of preventive medicine at Northwestern University Feinberg School of Medicine.
Lifestyle factors are most likely the main driver of cardiovascular events in men, a cardiologist suggests. (iStock)
“Our findings highlight the importance of promoting heart health screening and prevention in young adulthood, especially for young men,” Freedman told Fox News Digital.
The researchers emphasized the importance of looking beyond standard measures of heart risk, like cholesterol or blood pressure, and considering a “broader range of biological and social factors.”
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Dr. Andrew Freeman, cardiologist and director of clinical cardiology at National Jewish Health in Denver, was not involved in the study but commented on the findings.
“We have always known that men tend to manifest and typically die earlier from things like heart attacks and strokes compared to women,” he told Fox News Digital.
The lead researcher recommends more frequent or early CT angiograms to help prevent cardiac events. (iStock)
Although the study did not identify why more men are predisposed to heart issues than women, Freeman said factors like hormonal differences, diet and physical activity could come into play.
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“The standard American lifestyle makes us all sick, and then men seem to be more prone to developing this disease earlier,” the cardiologist told Fox News Digital.
“We are more exposed to toxins than ever before in virtually every part of our food supply,” he added. “We already know well that air pollution, light pollution and sound pollution are all associated with earlier heart disease.”
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Americans are also more sedentary, get less sleep, are more stressed and are less socially connected, all of which can increase cardiovascular diseases, Freeman added.
“I think this study is really underscoring that it’s time for some big changes,” he said.
Regular daily exercise is one way to set up your heart for a long life, experts agree. (iStock)
The doctor shared the following five “healthspan” tips to help prevent heart health issues.
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- Limit toxin exposure in the form of alcohol, tobacco, marijuana, nicotine and air pollution
- Eat a predominately low-fat, whole-food, plant-based diet
- Exercise regularly, ideally 20 to 30 minutes every day at a level of breathlessness (with sign-off from a doctor)
- Partake in stress-relieving activities and mindfulness exercises
- Get adequate, uninterrupted sleep
- Cultivate a strong support network of friends and family
“We need to do everything we can to clean up our lifestyles and reduce our disease burden.”
Freeman also recommends addressing any comorbidities, like high blood pressure, high cholesterol and obesity.
Those at a higher risk of cardiovascular events may want to consider earlier screening, although Freeman suggested that early prevention efforts should apply to everyone.
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“Coronary disease is manifesting earlier than ever here in the U.S., and we need to do everything we can to clean up our lifestyles and reduce our disease burden,” he said. “If you’re a man, you’ve got to be extra aggressive earlier in life.”
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