Science
A virus without a vaccine or treatment is hitting California. What you need to know
A respiratory virus that doesn’t have a vaccine or a specific treatment regimen is spreading in some parts of California — but there’s no need to sound the alarm just yet, public health officials say.
A majority of Northern California communities have seen high concentrations of human metapneumovirus, or HMPV, detected in their wastewater, according to data from the WastewaterScan Dashboard, a public database that monitors sewage to track the presence of infectious diseases.
A Los Angeles Times data analysis found the communities of Merced in the San Joaquin Valley, and Novato and Sunnyvale in the San Francisco Bay Area have seen increases in HMPV levels in their wastewater between mid-December and the end of February.
HMPV has also been detected in L.A. County, though at levels considered low to moderate at this point, data show.
While HMPV may not necessarily ring a bell, it isn’t a new virus. Its typical pattern of seasonal spread was upended by the COVID-19 pandemic, and its resurgence could signal a return to a more typical pre-coronavirus respiratory disease landscape.
Here’s what you need to know.
What is HMPV?
HMPV was first detected in 2001, according to the U.S. Centers for Disease Control and Prevention. It’s transmitted by close contact with someone who is infected or by touching a contaminated surface, said Dr. Neha Nanda, chief of infectious diseases and hospital epidemiologist for Keck Medicine of USC.
Like other respiratory illnesses, such as influenza, HMPV spreads and is more durable in colder temperatures, infectious-disease experts say.
Human metapneumovirus cases commonly start showing up in January before peaking in March or April and then tailing off in June, said Dr. Jessica August, chief of infectious diseases at Kaiser Permanente Santa Rosa.
However, as was the case with many respiratory viruses, COVID disrupted that seasonal trend.
Why are we talking about HMPV now?
Before the pandemic hit in 2020, Americans were regularly exposed to seasonal viruses like HMPV and developed a degree of natural immunity, August said.
That protection waned during the pandemic, as people stayed home or kept their distance from others. So when people resumed normal activities, they were more vulnerable to the virus. Unlike other viruses, there isn’t a vaccine for human metapneumovirus.
“That’s why after the pandemic we saw record-breaking childhood viral illnesses because we lacked the usual immunity that we had, just from lack of exposure,” August said. “All of that also led to longer viral seasons, more severe illness. But all of these things have settled down in many respects.”
In 2024, the national test positivity for HMPV peaked at 11.7% at the end of March, according to the National Respiratory and Enteric Virus Surveillance System. The following year’s peak was 7.15% in late April.
So far this year, the highest test positivity rate documented was 6.1%, reported on Feb. 21 — the most recent date for which complete data are available.
While the seasonal spread of viruses like HMPV is nothing new, people became more aware of infectious diseases and how to prevent them during the pandemic, and they’ve remained part of the public consciousness in the years since, August and Nanda said.
What are the symptoms of HMPV?
Most people won’t go to the doctor if they have HMPV because it typically causes mild, cold-like symptoms that include cough, fever, nasal congestion and sore throat.
HMPV infection can progress to:
- An asthma attack and reactive airway disease (wheezing and difficulty breathing)
- Middle ear infections behind the ear drum
- Croup, also known as “barking” cough — an infection of the vocal cords, windpipe and sometimes the larger airways in the lungs
- Bronchitis
- Fever
Anyone can contract human metapneumovirus, but those who are immunocompromised or have other underlying medical conditions are at particular risk of developing severe disease — including pneumonia. Young children and older adults are also considered higher-risk groups, Nanda said.
What is the treatment for HMPV?
There is no specified treatment protocol or antiviral medication for HMPV. However, it’s common for an infection to clear up on its own and treatment is mostly geared toward soothing symptoms, according to the American Lung Assn.
A doctor will likely send you home and tell you to rest and drink plenty of fluids, Nanda said.
If symptoms worsen, experts say you should contact your healthcare provider.
How to avoid contracting HMPV
Infectious-disease experts said the best way to avoid contracting HMPV is similar to preventing other respiratory illnesses.
The American Lung Assn.’s recommendations include:
- Wash your hands often with soap and water. If that’s not available, clean your hands with an alcohol-based hand sanitizer.
- Clean frequently touched surfaces.
- Crack open a window to improve air flow in crowded spaces.
- Avoid being around sick people if you can.
- Avoid touching your eyes, nose and mouth.
Assistant data and graphics editor Vanessa Martínez contributed to this report.
Science
In Venice, an Ocean-Inspired Exhibition Takes Visitors Under the Sea
Over the next month, if you take a ferry from the center of Venice to the island of Giudecca and walk into a former 15th-century convent, you will find yourself figuratively plunging underwater.
The haunting songs of humpback whales will flow around you. A fish will sing its evensong from the sea grass meadows of the Mediterranean. Boats recorded from beneath the surface of the Venetian lagoon will buzz like insects. A galaxy of bioluminescent plankton will glimmer in the sloshing waves.
This audiovisual symphony is part of “As Above, So Below,” a collateral exhibit running during the first month of the Venice Biennale, from Saturday through June 8. The exhibition brings together works by seven artists and art collectives who combine cutting-edge science and technology with traditional methods. Their installations surround visitors with natural sounds, merge their perspectives with those of other species and take them on an immersive journey into the sea, the soil and even a tree to highlight humans’ interdependence with the natural world.
As Elizabeth Zhivkova, a co-curator of the exhibition, put it: “‘As Above, So Below’ emerged from a shared urgency to rethink our relationship with nature, not as something separate from us, but as an interconnected system in which human, ecological and cosmic rhythms reflect one another.”
In addition to the exhibition, “As Above, So Below” is an ongoing research project that includes artist residencies and a podcast featuring conversations with artists and ocean advocates.
The project was born out of a partnership between Zeitgeist19, an environmental curatorial collective founded by Zhivkova and the show’s other co-curator, Farah Piriye Coene, and One Ocean Foundation, a scientific conservation organization based in Milan.
The name, “As Above, So Below,” comes from the Principle of Correspondence in Hermeticism, a spiritual tradition that blends Greek and Egyptian philosophies. It serves as a reminder that everything is connected. “The sea, the soil, the atmosphere, the human body are not separate realms; they are part of one relational field,” Coene said. “The exhibition asks whether art can help us feel that relation again.”
The exhibition’s setting in the former convent and church of Santi Cosma e Damiano — now a science and art innovation hub — fosters a contemplative atmosphere. In lieu of a central altarpiece, visitors encounter an immersive installation from the London-based artist collective Marshmallow Laser Feast, titled “Seeing Echoes in the Mind of the Whale.” In the work, a large-screen video immerses viewers in the sensory perspectives of a bottlenose dolphin, a humpback whale and a sperm whale as they dive and resurface to breathe.
The video plays recordings of dolphins’ trilling whistles, humpbacks’ meditative melodies and sperm whales’ Morse code-like clicks, which resonate throughout the space. To illustrate the use of echolocation to “see” through sound, these vocalizations are coordinated with visual effects. Shimmering swirls and pulsating pixels surround you, giving a sense of what bottlenose dolphins might “see” as they sweep sonar beams across colorful coral reefs, or what sperm whales might sense by blasting clicks to spy giant squid in the dark depths.
Ersin Han Ersin, one of the Marshmallow Laser Feast artists, explained in a video interview that the aim was for audiences to “disembody their own body, and momentarily embody what it is like to be a bottlenose dolphin or a whale.”
While visually speculative, the video is rooted in research. The members of the collective pored over scientific papers, compiled extensive hydrophone recordings and underwater videography, and collaborated with marine biologists and bioacousticians to dive into the sensory experiences of whales and dolphins, Ersin said.
In the process, he said, the artists became more sensitive to the ways noise pollution — the squeals of military sonar, the drumming of shipping traffic and the boom of seismic blasting to find fossil fuels — may be turning the ocean into an acoustic dystopia for animals and plants that live underwater.
“One part of me wants to scream that we are ruining these oceans, but the other part of me knows the best action is always cultivated from a place of love,” Ersin said. That is one goal of the installation, he added: To “make people fall in love with species that they never thought they can relate to.”
In another installation, “Fish String Theory,” Antoine Bertin, an artist who splits his time between Paris and Alicudi island, Italy, amplifies the surprisingly talkative world of fish. Bertin was inspired by reports of a “kwa” sound emanating from Mediterranean seagrass meadows. Scientists found that the kwa chorus most likely comes from scorpionfish. These venomous creatures have a muscular apparatus that functions like an internal violin.
Bertin made underwater recordings of scorpionfish and created fish-shaped sculptures with strings. When his recordings of scorpionfish play, the frequencies from the recordings activate electromagnets that vibrate the strings on the fish sculptures, creating a sound similar to a guitar or harp. The installation also includes Bertin’s underwater recordings of the Venetian lagoon, forming a dialogue between the scorpionfish song and the city’s aquatic soundscape.
Bertin is fascinated by the fact that life emerged in primordial seas, and said in an interview that he hoped that his installation would help people “return to the ocean as listeners.” His aim, he added, was to “create an experience that connects humans and fish in a sort of co-presence, to find out if we can resonate together.”
In “Water Older Than the Sun (Caspian),” the Kazakhstan-born artist Almagul Menlibayeva connects viewers to the Caspian Sea, which is shrinking because of climate change and water diversion — and being contaminated by drilling for oil and gas.
Menlibayeva pointed out that modern societies often see water as a resource to be used. She said in an interview that her installation positions water as an archive of deep time and as a “cosmic, alive entity.” As the title suggests, water is older than the sun because this cosmic compound formed as a result of supernovae explosions, then eventually came to Earth and condensed into oceans that gave rise to life. As such, “water has a memory,” Menlibayeva said, adding: “Water witnessed us as we appeared.”
At the center of Menlibayeva’s installation is a textile made from hand-sewn fabrics and A.I.-generated images of her artwork printed on synthetic silk that depict water, animals and robot-like humans. Fishing nets collected from the Caspian Sea dangle around the textile. Screens placed on the floor like a shoreline show surreal images, such as hands sewing water. Projected behind these pieces is “Requiem for the Caspian” by the London-based filmmaker Suad Gara, a short documentary that reveals the impact of the sea’s collapse on local people.
Just inside the entrance of the church, the Azerbaijan-born artist Elnara Nasirli has turned a reclaimed Italian olive tree into an instrument in “Whispering Forest.” Nasirli translated trees’ bioelectric rhythms into music and vibrations that softly play from contact points triggered by motion detection. Only by touching or hugging the tree, or leaning in very close and listening carefully, can visitors fully hear its whispered song.
Also in the exhibition, artworks bring viewers up close to underground mycelial networks, a holographic jellyfish and bioluminescent plankton that spell out “No blue, no green,” a quote from the marine biologist Sylvia Earle about the vital importance of marine ecosystems.
Altogether, the exhibition invites people to attune to the intelligence and voices of other species and, as Bertin said, to “stretch their sense of self to include the vastness of the ocean.”
Science
Deadly hantavirus outbreak strikes luxury cruise. What you should know about the disease
A suspected outbreak of hantavirus, a rare but deadly disease that attacks the lungs, has left three people dead and several others severely ill aboard a luxury cruise ship.
Here’s what we know about the voyage and the virus that also made headlines last year after it killed Gene Hackman’s 65-year-old wife, Betsy Arakawa.
What’s going on?
Global health officials and the cruise operator, Oceanwide Expeditions, are investigating and working to contain the illnesses suspected to have been brought on by the rodent-borne illness aboard the MV Hondius — a Dutch-flagged ship, according to the World Health Organization.
On Monday, the WHO announced that the luxury ship carrying 147 passengers and crew had two laboratory-confirmed cases and five suspected cases of hantavirus. The three deaths are included in that total.
The cruise ship, which was on a 46-day journey that traveled from Antarctica with stops in Argentina, has remained off the coast of Cape Verde in the Atlantic Ocean. During a news conference, WHO officials said they’re planning to medically evacuate two individuals with suspected infections.
The vessel departed Ushuaia, Argentina, on April 1 and traveled across the Atlantic with multiple stops in remote and ecological diverse regions, according to the WHO.
“The extent of passenger contact with local wildlife during the voyage, or prior to boarding in Ushuaia, remains undetermined,” the organization said in a statement.
What we know about hantavirus
Typically, hantavirus spreads by inhaling particles contaminated with the urine, feces or saliva of wild rodents.
“What we don’t know about this current outbreak is whether someone got onto the ship and was already sick or there were rodents on the cruise,” said Dr. Gaby Frank, director of the Johns Hopkins Special Pathogens Center.
There is, however, a strain of hantavirus that can be spread from human to human, known as the Andes virus, Frank said.
In such a case, a person would first be infected by a wild rodent’s contaminated particles and then, after becoming infected themselves, pass the infection to another person.
There are 50 species of hantavirus. The virus that’s found in the Americas tends to cause a cardiopulmonary syndrome, a condition that affects the heart and the lungs, according to Frank.
There have been 890 laboratory-confirmed cases of hantavirus disease reported in the United States since surveillance began in 1993, according to the most recent data from the U.S. Centers for Disease Control and Prevention.
The data suggest that contracting hantavirus is rare, said Dr. Afif El-Hasan, member of the American Lung Assn.’s national board of directors.
“That being said, it’s probably underdiagnosed because the symptoms are a lot like the flu or other illness,” El-Hasan said. “And a lot of people may have passed away or had hantavirus, but it was never diagnosed.”
There is no vaccine or specific antiviral medicine for hantavirius.
The ICU treatment may include intubation and oxygen therapy, fluid replacement and use of medications to lower blood pressure, according to the American Lung Assn.
Know the signs of hantavirus and next steps
Early symptoms of hantavirus are similar to the flu and include fatigue, fever and muscle aches, according to the CDC. Signs of these symptoms start to show within one to eight weeks after contact with an infected rodent.
Half of those who contract the virus also experience headaches, dizziness, chills, nausea, vomiting, diarrhea and abdominal pain.
Four to 10 days after the initial phase of the illness, another round of symptoms can develop, which include coughing, shortness of breath and possible tightness in the chest as the lungs fill with fluid.
Even though contracting hantavirus in the United States continues to be a rare event, El-Hasan said, people should take these initial symptoms seriously and promptly seek medical care.
Hantavirus can be deadly. CDC officials said 38% of people who develop respiratory symptoms may die from the disease.
How to protect yourself
Hantavirus cases can occur year-round, but the peak seasons in the United States are in the spring and summer, which coincide with the reproductive seasons for deer mice.
To lessen your risk of infection, keep wild rodents out of your home, workplace, shed, cabin, car or other enclosed spaces.
Los Angeles County public health officials offer suggestions on how you can keep rodents at bay, which include:
- Sealing up holes, the width of a pencil or larger, that mice can squeeze into.
- Place snap traps to catch any rodents. The CDC cautions against using glue or live traps because they can scare the rodents, causing them to urinate, which increases your chances of exposure to any virus they may be carrying.
- Store all food items in rodent-proof containers.
If you find evidence of mice in a space that you frequent, local and state officials advise:
- Before you clean, air out the space for 30 minutes. Equip yourself with rubber or plastic gloves, an N-95 mask and a disinfectant or mixture of bleach and water.
- While cleaning, spray the contaminated areas with your disinfectant and let it soak for at least five minutes. Do not sweep or vacuum the area, the movement could stir up the infectious materials in the air. Instead, use paper towels, a sponge or a mop to clean. When you’re done, put everything, including cleaning materials, in a bag and toss it in your trash bin.
Science
The Uncertain Fate of France’s Last Two Captive Orcas
At a closed marine park in the south of France, two orcas swim lonely circles in an aging tank, its walls caked with green algae. Their fate has become a drama in France, where the government must decide soon whether to transfer them to another marine park or release them into a sanctuary in the sea.
While the prospect of sending them into nature is appealing, evoking a sense of restitution for captive mammals, critics argue it is both experimental and unrealistic. These orcas — a female, Wikie, 25, and her son Keijo, 13 — were born in Marineland, the shuttered park in Antibes, and have never had to survive in the wild.
The park closed in January 2025 after 55 years, a victim of the coronavirus pandemic, which crushed attendance, and animal welfare legislation from 2021. The law banned most shows involving marine mammals like orcas, reducing the park’s appeal to tourists.
Since the closure, about 40 employees have come each day to care for the mammals — in addition to the orcas, there are 12 dolphins — at a cost of several million euros a year, according to Marineland.
That arrangement may soon be untenable. A report this year warned that the orcas’ tanks were suffering “progressive structural deterioration” despite maintenance. A major structural failure might prompt the park owners to euthanize the orcas, also known as killer whales.
Some accuse the government of dragging its feet in finding a solution.
“I just get this feeling that they’re just waiting for the orcas to die to solve the problem,” said Paul Watson, founder of the Sea Shepherd Conservation Society, an antipoaching and marine-conservation group. He is lobbying for European countries to finance the construction of a marine sanctuary in Europe.
Last June, Mr. Watson recalled, President Emmanuel Macron of France promised him on television that he would help find a solution for the orcas. “We haven’t heard anything since,” he said.
The French government declined an interview request but has released several updates about its efforts to find a solution. But “there’s no magical sanctuary,” said Mathieu Lefèvre, France’s deputy minister for ecological transition, during a Senate hearing in April.
There are two options. France can either transfer the orcas to a park similar to Marineland, most likely Loro Parque on the Spanish island of Tenerife. Or it can move them to an area at sea protected by nets, like a planned 100-acre open-water sanctuary in a cove on the Canadian coast, called the Whale Sanctuary Project.
This kind of sanctuary would allow handlers to care for the mammals in a natural setting, without public performances. That contrasts with the fate of Keiko, the orca who starred in the 1993 feature film “Free Willy.” He was later released into the wild, without human protection, and struggled to adapt.
Each option has its obstacles. The French government initially said its preference was to send the orcas to the Canadian site. But months later, the site isn’t ready and experts are still debating if it’s an appropriate habitat for the whales, derailing the French plan. And the Spanish authorities have blocked the orcas’ transfer to Spain, the French government said in December.
Even among marine experts and activists, there is no consensus about the best solution.
Moving captive-born orcas to natural environments doesn’t guarantee their well-being, according to critics of the Canadian plan, since the orcas’ ability to adapt to that new context is not assured. Such sites may be polluted or noisy, creating more stress for the orcas, and they are also expensive to maintain.
“These solutions appear more appealing to our human eyes than they do for the daily lives of these animals,” said Martin Böye, scientific director at Loro Parque Foundation, which already owns four orcas. Wikie and Keijo need interactions with other orcas in a familiar environment, he added.
Mr. Watson warned that because these orcas were raised in a Mediterranean climate, they would not be acclimated to a Canadian one. He also noted that the nearby shoreline used to have a gold mine, raising concerns about contaminated water — though the Whale Sanctuary Project says that its studies showed the site was safe.
“On paper, it’s a great solution, but in practice it’s impossible,” said Valentin Ducros, a spokesman for Marineland.
Supporters of the open-water option counter that parks have a vested interest in keeping orcas captive, since it makes it easier for them to breed new generations of killer whales, sustaining their business model.
Critics fault the French government for passing the law restricting marine shows without planning for the future of their former stars. Anne Chain-Larché, a senator who worked on the law, deplored that no impact assessment was produced and that decrees clarifying the law took too much time to be drafted for parks to adapt.
Now, the orcas are paying the price for that lack of foresight, said Marketa Schusterova, a founder of TideBreakers, a Canadian nonprofit that protects marine mammals.
“How can we be screaming, ‘Empty the tanks,’ and have nowhere for these animals to go?” Ms. Schusterova said.
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