Health
New study hints at a hidden Alzheimer’s risk factor affecting older Americans
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People with greater exposure to air pollution could face a higher risk of developing Alzheimer’s disease, according to a new study by Emory University in Atlanta.
Air pollution has previously been established as a risk factor for Alzheimer’s, as well as other chronic conditions, like hypertension, stroke and depression, the researchers noted.
Since those other conditions are themselves linked to Alzheimer’s, the researchers said it’s not yet clear whether air pollution harms brain health on its own, or whether it raises dementia risk by first triggering those other health problems.
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The study, which was published in the journal PLOS Medicine, investigated more than 27.8 million U.S. Medicare recipients, 65 years and older, from 2000 to 2018.
The individuals were examined for level of exposure to air pollution and whether they developed Alzheimer’s, with a focus on other chronic conditions.
Air pollution may have a direct correlation to Alzheimer’s diagnoses, a new study found. (iStock)
Greater exposure to air pollution was associated with an increased risk of Alzheimer’s, which was slightly stronger in people who had experienced a stroke. Hypertension and depression had “little additional impact,” according to the study’s press release.
The authors concluded that air pollution leads to Alzheimer’s mostly through “direct pathways” rather than via other chronic conditions.
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“Our findings suggest that individuals with a history of stroke may be particularly vulnerable to the harmful effects of air pollution on brain health, highlighting an important intersection between environmental and vascular risk factors,” the authors wrote in a statement.
These findings suggest that improving air quality could be “an important way to prevent dementia and protect older adults,” the press release concluded.
Air quality could be “an important way to prevent dementia and protect older adults,” the researchers suggested. (iStock)
Fox News senior medical analyst Dr. Marc Siegel confirmed more studies are revealing that Alzheimer’s is linked to conditions that impact the brain, which can be “sensitive and fragile.”
“Certainly, underlying medical conditions like stroke can lead to this,” Siegel, who was not involved in the study, told Fox News Digital.
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This latest study “does not show cause and effect,” the doctor noted, but rather shows an “increasing association between air pollution and Alzheimer’s, where the particulate matter appears to increase the inflammation in the brain that helps lead to it.”
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“This is another piece in developing a strategy of prevention, early diagnosis and targeted treatments,” Siegel added.
People with a history of stroke could be more susceptible to air pollution risks, according to the researchers. (iStock)
Ozama Ismail, PhD, director of scientific programs at the Alzheimer’s Association in Chicago, agreed that this study adds to existing research on the impact of air pollution and overall health, especially related to the brain.
“Alzheimer’s is a complex disease, and it is likely that there are a variety of factors … that impact a person’s lifetime risk.”
“This is an area of investigation where more research is vital to helping us better understand the connection between pollution and the various factors that cause or contribute to Alzheimer’s disease,” Ismail, who also did not work on the study, told Fox News Digital.
“Previous studies, including those presented at the Alzheimer’s Association International Conference in 2019, 2021 and 2025, have shown evidence for connections between exposure to air pollution and other environmental toxins and risk for Alzheimer’s or other dementias.”
“Avoiding exposure to air pollution is a risk factor that may be easier for some people to change than others,” one expert said. (iStock)
The Lancet Commission on Dementia Prevention added exposure to air pollution to its list of known dementia risk factors in 2020, according to Ismail.
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“We know that Alzheimer’s is a complex disease, and it is likely that there are a variety of factors, in combination, that impact a person’s lifetime risk,” he said. “Avoiding exposure to air pollution is a risk factor that may be easier for some people to change than others.”
Fox News Digital reached out to the study authors for comment.
Health
Heart disease threat projected to climb sharply for key demographic
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A new report by the American Heart Association (AHA) included some troubling predictions for the future of women’s health.
The forecast, published in the journal Circulation on Wednesday, projected increases in various comorbidities in American females by 2050.
More than 59% of women were predicted to have high blood pressure, up from less than 49% currently.
The review also projected that more than 25% of women will have diabetes, compared to about 15% today, and more than 61% will have obesity, compared to 44% currently.
As a result of these risk factors, the prevalence of cardiovascular disease and stroke is expected to rise to 14.4% from 10.7%.
The prevalence of cardiovascular disease and stroke in women is expected to rise to 14.4% from 10.7% by 2050. (iStock)
Not all trends were negative, as unhealthy cholesterol prevalence is expected to drop to about 22% from more than 42% today, the report stated.
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Dr. Elizabeth Klodas, a cardiologist and founder of Step One Foods in Minnesota, commented on these “jarring findings.”
“The fact that on our current trajectory, cardiometabolic disease is projected to explode in women within one generation should be a huge wake-up call,” she told Fox News Digital.
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“Hypertension, diabetes, obesity — these are all major risk factors for heart disease, and we are already seeing what those risks are driving. Heart disease is the No. 1 killer of women, eclipsing all other causes of death, including breast cancer.”
Cardiovascular disease is the leading cause of death for women in the U.S. and around the world. (iStock)
Klodas warned that heart disease starts early, progresses “stealthily,” and can present “out of the blue in devastating ways.”
The AHA published another study on Thursday revealing one million hospitalizations, showing that heart attack deaths are climbing among adults below the age of 55.
The more alarming finding, according to Klodas, is that young women were found more likely to die after their first heart attack than men of the same age.
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“This is all especially tragic since heart disease is almost entirely preventable,” she said. “The earlier you start, the better.”
Children can show early evidence of plaque deposition in their arteries, which can be reversed through lifestyle changes if “undertaken early enough and aggressively enough,” according to the expert.
Moving more is one part of protecting a healthy heart, according to experts. (iStock)
Klodas suggested that rising heart conditions are associated with traditional risk factors, like smoking, high blood pressure, high cholesterol, diabetes, obesity and a sedentary lifestyle.
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Doctors are also seeing higher rates of preeclampsia, or high blood pressure during pregnancy, as well as gestational diabetes. Klodas noted that these are sex-specific risk factors that don’t typically contribute to complications until after menopause.
The best way to protect a healthy heart is to “do the basics,” Klodas recommended, including the following lifestyle habits.
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Klodas especially emphasized making improvements to diet, as the food people eat affects “every single risk factor that the AHA’s report highlights.”
“High blood pressure, high blood sugar, high cholesterol, excess weight – these are all conditions that are driven in part or in whole by food,” she said. “We eat multiple times every single day, which means what we eat has profound cumulative effects over time.”
“Even a small improvement in dietary intake, when maintained, can have a massive positive impact on health,” a doctor said. (iStock)
“Even a small improvement in dietary intake, when maintained, can have a massive positive impact on health.”
The doctor also recommends changing out a few snacks per day for healthier choices, which has been proven to “yield medication-level cholesterol reductions” in a month.
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“Keep up that small change and, over the course of a year, you could also lose 20 pounds and reduce your sodium intake enough to avoid blood pressure-lowering medications,” Klodas added.
“Women should not view the AHA report as inevitable. We have power over our health destinies. We just need to use it.”
Health
Vanessa Williams, 62, Opens up About Weight Loss and HRT After Menopause
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Health
Common vision issue linked to type of lighting used in Americans’ homes
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Nearsightedness (myopia) is skyrocketing globally, with nearly half of the world’s population expected to be myopic by 2050, according to the World Health Organization.
Heavy use of smartphones and other devices is associated with an 80% higher risk of myopia when combined with excessive computer use, but a new study suggests that dim indoor lighting could also be a factor.
For years, scientists have been puzzled by the different ways myopia is triggered. In lab settings, it can be induced by blurring vision or using different lenses. Conversely, it can be slowed by something as simple as spending time outdoors, research suggests.
Nearsightedness occurs when the eyeball grows too long from front to back, according to the American Optometric Association (AOA). This physical elongation causes light to focus in front of the retina rather than directly on it, making distant objects appear blurry.
The study suggests that myopia isn’t caused by the digital devices themselves, but by the low-light environments where they are typically used. (iStock)
Researchers at the State University of New York (SUNY) College of Optometry identified a potential specific trigger for this growth. When someone looks at a phone or a book up close, the pupil naturally constricts.
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“In bright outdoor light, the pupil constricts to protect the eye while still allowing ample light to reach the retina,” Urusha Maharjan, a SUNY Optometry doctoral student who conducted the study, said in a press release.
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“When people focus on close objects indoors, such as phones, tablets or books, the pupil can also constrict — not because of brightness, but to sharpen the image,” she went on. “In dim lighting, this combination may significantly reduce retinal illumination.”
High-intensity natural light prevents myopia because it provides enough retinal stimulation to override the “stop growing” signal, even when pupils are constricted. (iStock)
The hypothesis suggests that when the retina is deprived of light during extended close-up work, it sends a signal for the eye to grow.
In a dim environment, the narrowed pupil allows so little light through that the retinal activity isn’t strong enough to signal the eye to stop growing, the researchers found.
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In contrast, being outdoors provides light levels much brighter than indoors. This ensures that even when the pupil narrows to focus on a nearby object, the retina still receives a strong signal, maintaining healthy eye development.
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The team noted some limitations of the study, including the small subject group and the inability to directly measure internal lens changes, as the bright backgrounds used to mimic the outdoors made pupils too small for standard equipment.
Researchers believe that increasing indoor brightness during close-up work could be a simple, testable way to slow the global nearsightedness epidemic. (iStock)
“This is not a final answer,” Jose-Manuel Alonso, MD, PhD, SUNY distinguished professor and senior author of the study, said in the release.
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“But the study offers a testable hypothesis that reframes how visual habits, lighting and eye focusing interact.”
The study was published in the journal Cell Reports.
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