The San Francisco 49ers (12-5) visit the Philadelphia Eagles (11-6) at Lincoln Financial Field in Philadelphia for a Wild Card round showdown as the NFL playoffs get underway. USA TODAY’s panel of NFL experts have locked in their picks and predictions for the action. Here’s everything you need to know before kickoff on Sunday, January 11, including live updated odds and injury report news.

Eagles vs. 49ers live odds, moneyline, over/under

Opening Lines

• Spread: Eagles (-3.5)
• Moneyline: Eagles (-190), 49ers (+155)
• Over/Under: 46.5

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Eagles vs. 49ers picks against the spread

Jon Hoefling: San Francisco 49ers (+4.5)

The Eagles feel like a lesser version of the Seattle Seahawks, and SF had several opportunities to win against Seattle in Week 18.

Tyler Dragon: Philadelphia Eagles (-4.5)

San Francisco has too many injuries. The 49ers will compete, but the Eagles are the best team in the tournament.

Lorenzo Reyes: San Francisco 49ers (+4.5)

This season, it was San Francisco’s defense that let it down. The lack of a pass rush and lack of turnovers kept games closer. The thing is, Philadelphia’s offense was also underwhelming, which was surprising given the talent on the roster. I think this is a case where the Niner offense carries the day, though injuries on defense are a concern. Either way, this line feels too big.

Christopher Bumbaca: Philadelphia Eagles (-4.5)

This is a “go with the best unit on the field” play. The one I’m talking about? The Philadelphia Eagles’ defense. Kyle Shanahan vs. Vic Fangio should be a treat though.

Jordan Mendoza: San Francisco 49ers (+4.5)

The defending champions have been up-and-down this season, and that gives San Francisco to catch the Eagles off guard. Brock Purdy finds his form to deliver a stunner.

Blake Schuster: Philadelphia Eagles (-4.5)

All San Francisco had to do was beat Seattle in Week 18 and it wouldn’t have had to leave home once during the postseason. Now the Niners have to go to Philly and face an Eagles team that’s probably furious after their season finale letdown. The Bay is about to experience some intense whiplash.

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