Health
Going to bed after this time could lead to poorer mental health, a Stanford study finds
Night owls might want to start turning in earlier.
A recent study by Stanford University, published in the journal Psychiatry Research, found that going to bed after 1:00 a.m. could lead to mental health issues.
Researchers analyzed the data of more than 73,000 adults in the U.K., looking into their chronotype (inclination to rise early or stay up late) and actual sleep timing.
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The study then examined the alignment between the two and the prevalence of mental, behavioral and neurodevelopmental disorders (MBN), as well as depression and anxiety.
People with a morning preference who go to bed early exhibit “better mental health” compared to morning types who go to bed late, the study found.
Overall, early birds seemed to have better mental health, according to a Stanford University research. (iStock)
Morning types who tend to go to bed late have an increased risk of MBNs, depression and anxiety.
People with an evening preference who sleep late were also found to demonstrate poorer mental health. Evening types who wake up early, conversely, have a lower risk of developing depression.
Based on these findings, the researchers recommended going to sleep before 1:00 a.m., regardless of preference.
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Study co-author Jamie Zeitzer, Ph.D., a professor at Stanford University’s department of psychiatry and behavioral sciences in California, said he was surprised by the results.
“They were not what we expected at all,” he wrote in an email to Fox News Digital. “We spent more than a year trying to disprove our findings, but could not find an alternate explanation.”
“We had expected that night owls who stayed up late would be OK, but they ended up being at a greater risk for developing mental health disorders than night owls who went to bed earlier,” one researcher said. (iStock)
The researchers originally anticipated that individuals who aligned their actual sleep timing with their morning/evening preference would have the best mental health, Zeitzer noted – but this was not the case.
“Rather, we found that being awake late at night, irrespective of preferred sleep timing, was associated with worse mental health,” he said.
Good sleep is “crucial for establishing a pillar of good mental health,” according to Zeitzer.
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“It is not necessarily [the case] that bad sleep causes poor mental health, but it can definitely facilitate poorer mental health,” he said.
“There are several aspects of sleep that contribute [to mental health], including the duration (which we accounted for in our study) and the timing (which we directly examined in our study).”
Not getting enough sleep has been proven to compromise mental health, according to a sleep expert. (iStock)
While it might not be detrimental for all night owls to stick to their preferred nighttime sleep schedule, Zeitzer said, the research highlights that it presents a risk for some.
“We are not clear as to why this is the case, but it may have to do with the isolation that often accompanies such late-night behavior,” he said.
“So, being aware of how you are spending your late nights and whether these behaviors are conducive to good mental health is crucial.”
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Dr. Wendy Troxel, a Utah-based sleep expert who was not involved in the study, agreed that the findings are “very interesting” – particularly the fact that going to bed later is associated with poorer mental health regardless of one’s natural tendency.
“These findings underscore that sleep health is a multidimensional state,” Troxel said in an interview with Fox News Digital.
“It’s not just about getting enough sleep or good quality sleep that matters, but the timing matters, too.”
“Going to bed excessively late on a regular basis may lead to impairments in decision-making and emotion regulation.”
Failing to get enough sleep has been proven to compromise mental health by “influencing brain mechanisms that help to regulate emotions,” she added.
“Going to bed excessively late (i.e., after 1 a.m.) on a regular basis may lead to impairments in decision-making and emotion regulation, which may underlie associations with mental health problems, such as depression and anxiety,” she said.
The study results are also interesting when applied to specific groups who tend to be night owls, like teenagers, Troxel noted.
“Biologically, teenagers are predisposed to stay awake later and sleep in later, which is in conflict with early school start times,” she said.
“This can set them up for a ‘double whammy’ of both insufficient sleep and delayed sleep schedules, which can contribute to mental health problems — a major public health issue among teenagers.”
Dr. Wendy Troxel, senior behavioral scientist for RAND Corporation, is the author of “Sharing the Covers: Every Couple’s Guide to Better Sleep” and is also a scientific advisor for the Sleep Foundation. (Diane Baldwin)
3 critical steps for better sleep
Troxel recommends taking the following steps to improve the quality of sleep.
First, slowly advance bedtime earlier by 15-minute increments each week.
Next, allow for plenty of sunlight in the morning, she advised, as sunlight is “one of the most powerful cues to help set the circadian rhythm.” In the evening, keep the lights low.
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It’s important to stay consistent with sleep schedules, even on the weekends, one sleep expert advised. (iStock)
Finally, stay consistent with your sleep schedule, including on weekends, Troxel suggested.
While this can be challenging, especially for night owls, reverting to a later bedtime and wake-up times will “set you back to square one,” she warned.
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The key to successfully shifting sleep habits is to do it gradually, Troxel said.
“It’s similar to the approach we would recommend for changing one’s schedule to manage jetlag,” she said.
Being aware of how you’re spending your late nights is “crucial” to good mental health, one of the study researchers said. (iStock)
Zeitzer noted that it can be difficult for anyone to switch up their sleep schedules, especially for those who prefer more “extreme times,” like staying up until 4:00 a.m. or waking up before 5:00 a.m.
Going to bed and waking up at the same time every day is the best way to successfully make a shift, he said, along with exposure to bright light.
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Collagen supplements have exploded in popularity, touted as everything from an anti-aging miracle to a muscle recovery booster.
But a sweeping new review conducted by U.K. researchers suggests that while collagen may help improve skin elasticity and ease arthritis pain, it does little for athletic performance or wrinkle reduction.
Researchers from Anglia Ruskin University analyzed 16 systematic reviews and 113 randomized controlled trials involving nearly 8,000 participants worldwide, which they say is the most extensive evaluation of collagen’s health effects to date.
The review found consistent evidence that collagen supplementation improves skin elasticity and hydration over time and provides significant relief from osteoarthritis-related joint pain and stiffness, according to findings published in Aesthetic Surgery Journal Open Forum.
A large U.K. review found that collagen supplements may improve skin elasticity and hydration over time. (iStock)
The researchers, however, did not find meaningful improvements in post-exercise muscle recovery, soreness or tendon mechanical properties (strength, springiness and stretch resistance).
“Collagen is not a cure-all, but it does have credible benefits when used consistently over time, particularly for skin and osteoarthritis,” co-author Lee Smith, professor of public health at Anglia Ruskin University, said in a statement.
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“Our findings show clear benefits in key areas of healthy aging, while also dispelling some of the myths surrounding its use,” Smith added.
Collagen, the most abundant protein in the body, supports skin, bones, tendons, cartilage and connective tissue, according to experts. Natural collagen production begins to drop in early adulthood and declines more sharply with age.
The study found that collagen supplements may help reduce joint pain and stiffness in people with osteoarthritis. (iStock)
The review found that long-term collagen supplementation was linked to improved skin firmness and hydration, but did not help skin roughness — a proxy for visible wrinkles.
Benefits appear to accumulate gradually, suggesting that collagen should not be viewed as an “anti-wrinkle ‘quick fix,’ but as a foundational dermal support for individuals seeking holistic skin maintenance,” the researchers said.
“If we define anti-aging as a product or technique designed to prevent the appearance of getting older, then I believe our findings do support this claim for some parameters,” Smith told the BBC. “For example, an improvement in skin tone and moisture is associated with a more youthful-looking appearance.”
Collagen supplementation was linked to reduced pain and stiffness in people with osteoarthritis, with stronger benefits seen over longer periods of use, and showed modest improvements in muscle mass and tendon structure that may support healthy aging.
Collagen did not significantly improve skin roughness, a marker of visible wrinkles. (iStock)
However, it did not show meaningful results when used as a fast-acting sports performance supplement, and evidence for benefits related to cholesterol, blood sugar, blood pressure and oral health was mixed or inconclusive.
Dr. Daniel Ghiyam, a California-based physician and longevity specialist, said the findings align with what he sees in clinical practice.
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“Collagen is a targeted support tool, not a foundation of health or performance,” Ghiyam, who was not involved in the study, told Fox News Digital. “When marketed that way, it makes sense. When marketed as a cure-all, it doesn’t hold up to the data.”
The authors noted that while many previous collagen studies have received financial support from the supplement industry, the current review did not receive industry funding.
Experts say collagen supplements may offer modest benefits for skin hydration and joint comfort, but they are not a cure-all. (iStock)
The team called for more high-quality clinical trials examining long-term outcomes, optimal dosages and differences between collagen sources, such as marine, bovine and plant-based alternatives.
Among its limitations, the review could not determine whether certain forms of collagen work better than others or what the optimal regimen should be.
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While the review included randomized controlled trials, the quality of the studies varied, with newer research generally showing stronger results.
Experts say more data and studies are needed to build on the findings. They also noted that diet plays a crucial role in skin health.
Collagen supplements, often sold as powders or pills, may improve skin elasticity and ease joint pain, experts say. (iStock)
Dr. Erum Ilyas, a Pennsylvania-based dermatologist and chair of dermatology at Drexel University College of Medicine, noted that the review analyzed previously published meta-analyses rather than generating new primary data.
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“At this time, I have not seen sufficiently strong independent evidence to routinely recommend collagen supplements to my patients,” Ilyas, who was not involved in the review, told Fox News Digital.
“Although some studies show modest improvements in markers such as hydration and elasticity, there remains limited independent, biopsy-confirmed evidence demonstrating sustained increases in dermal collagen content,” she added.
Fox News Digital has reached out to the researchers for comment.
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As colorectal cancer (CRC) is now the leading cause of cancer death in adults under 50, a new report reveals some surprising shifts in the incidence of the disease.
Although rates of CRC have been declining among seniors, those 65 and under are facing a rise in diagnoses, according to a report titled Colorectal Cancer Statistics, 2026, from the American Cancer Society.
Adults 65 and younger comprise nearly half (45%) of all new colorectal cancer cases — a significant increase from 27% in 1995, states the report, which was published in CA: A Cancer Journal for Clinicians.
The disease is rising fastest among adults 20 to 49 years old, at a rate of 3% per year.
Colorectal cancer is now the leading cause of cancer death in adults under 50. (iStock)
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. Although that age group is eligible to receive routine screenings, just 37% do so.
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The report also revealed that rectal cancer is on the rise, now accounting for about one-third (32%) of all CRC cases — an increase from 27% in the mid-2000s.
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“After decades of progress, the risk of dying from colorectal cancer is climbing in younger generations of men and women, confirming a real uptick in disease because of something we’re doing or some other exposure,” said Rebecca Siegel, senior scientific director, surveillance research at the American Cancer Society and lead author of the report, in a press release.
Among adults 50 and under, 75% of colorectal cancers are diagnosed at an advanced stage. Half of the diagnoses in that age range are made between the ages of 45 and 49. (iStock)
“We need to redouble research efforts to understand the cause, but also circumvent deaths through earlier detection by educating clinicians and the general public about symptoms and increasing screening in people 45-54 years.”
It is projected that 158,850 new cases of colorectal cancer will be diagnosed this year, and that the disease will cause 55,230 deaths, per the report.
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More than half of CRC cases can be linked to high-risk behaviors, the researchers said. Those include lack of nutrition, high alcohol consumption, smoking, lack of exercise and obesity.
“These findings further underscore that colorectal cancer is worsening among younger generations and highlight the immediate need for eligible adults to begin screening at the recommended age of 45,” said Dr. William Dahut, chief scientific officer at the American Cancer Society.
When the disease is caught at a local (early) stage, the five-year survival rate is 95%. (iStock)
“The report also shines a light on the crucial importance of continued funding for research to help discover new therapies to treat the disease and advance patient care.”
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When the disease is caught at a local (early) stage, the five-year survival rate is 95%, the report stated.
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A new study suggests that middle-aged men may be more vulnerable to faster biological aging, potentially linked to exposure to “forever chemicals.”
The research, published in the journal Frontiers in Aging, examined how perfluoroalkyl and polyfluoroalkyl substances, more commonly known as PFAS, could impact aging at the cellular level.
PFAS are synthetic chemicals commonly used in nonstick cookware, food packaging, water-resistant fabrics and other consumer products, the study noted.
Their chemical structure makes them highly resistant to breaking down, allowing them to accumulate in water, soil and the human body.
Chinese researchers analyzed blood samples from 326 adults enrolled in the U.S. National Health and Nutrition Examination Survey between 1999 and 2000.
A new study suggests that middle-aged men could face accelerated biological aging at the cellular level due to exposure to PFAS. (iStock)
The researchers measured levels of 11 PFAS compounds in participants’ blood and used DNA-based “epigenetic clocks” — tools that analyze chemical changes to DNA to estimate biological age — to determine how quickly their bodies were aging at the cellular level, the study stated.
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Two compounds, perfluorononanoic acid (PFNA) and perfluorooctanesulfonamide (PFOSA), were detected in 95% of participants.
Higher concentrations of those chemicals were associated with faster biological aging in men of certain age groups, but not in women.
“People should not panic.”
The compounds most strongly linked to accelerated aging were not the PFAS chemicals that typically receive the most public attention, the researchers noted.
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“The associations were strongest in adults aged 50 to 64, particularly in men,” Dr. Xiangwei Li, professor at Shanghai Jiao Tong University School of Medicine and the study’s corresponding author, told Fox News Digital.
“While this does not establish that PFAS cause aging, it suggests that these widely present ‘forever chemicals’ may be linked to molecular changes related to long-term health and aging.”
The study found that two of the compounds were detected in 95% of participants, and higher levels were linked to faster biological aging in men ages 50–64. (iStock)
Midlife may represent a more sensitive biological period, when the body becomes more vulnerable to age-related stressors, according to the researchers.
Lifestyle factors, such as smoking, may influence biological aging markers, potentially increasing vulnerability to environmental pollutants.
While Li said “people should not panic,” she does recommend looking for reasonable ways to reduce exposure.
That might mean checking local drinking water reports, using certified water filters designed to reduce PFAS, and limiting the use of stain- or grease-resistant products when alternatives are available.
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Meaningful reductions in PFAS exposure will likely depend on broader regulatory action and environmental cleanup efforts, Li added.
The researchers noted that midlife could be a particularly sensitive stage, when the body is more susceptible to stressors associated with aging. (iStock)
Study limitations
The researchers outlined several important limitations of the research, including that the findings show an association, but do not prove that PFAS directly causes accelerated aging.
“The study is cross-sectional, meaning exposure and aging markers were measured at the same time, so we cannot determine causality,” Li told Fox News Digital.
The study was also relatively small, limited to 326 adults age 50 or older, which means the findings may not apply to younger people or broader populations.
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Researchers measured PFAS levels using data collected between 1999 and 2000, and today’s exposure patterns may differ.
Li added that while PFAS is known to persist in the environment and the body, these results should be validated through larger, more recent studies that follow participants over time.
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